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GO:0008725 DNA-3-methyladenine glycosylase I activityCatalysis of the hydrolysis of alkylated DNA; only recognizes and removes the alkylated base 3-methyladenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.
Term Information
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| Type | Synonym |
| exact | DNA-3-methyladenine glycosidase I activity |
| related | DNA glycosidase I activity |
| broad | alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine) |
| related | deoxyribonucleate 3-methyladenine glycosidase I |
| related | 3-methyladenine DNA glycosylase I |
| Database | ID |
| EC | 3.2.2.20 |
| INTERPRO | IPR004597 |
| MetaCyc | 3.2.2.20-RXN |
| INTERPRO | IPR005019 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||||
![]() | GO:0003824 catalytic activity | ||||||
![]() | ![]() | GO:0016787 hydrolase activity | |||||
![]() | ![]() | ![]() | GO:0016798 hydrolase activity, acting on glycosyl bonds | ||||
![]() | ![]() | ![]() | ![]() | GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0019104 DNA N-glycosylase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0003905 alkylbase DNA N-glycosylase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0008725 DNA-3-methyladenine glycosylase I activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-12-12-04-02-05 |