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GO:0008696 4-amino-4-deoxychorismate lyase activity

Term Information

ID GO:0008696
Name 4-amino-4-deoxychorismate lyase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate.
Comment Note that the name 'para-amino benzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate.
GONUTS GO:0008696 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related p-aminobenzoate synthetase
related para-aminobenzoic acid (PABA) synthase
exact 4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)
exact 4-amino-4-deoxychorismate pyruvate-lyase activity
exact ADC lyase activity
related enzyme X activity
exact aminodeoxychorismate lyase activity
related para-aminobenzoic acid synthase

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 4.1.3.38
InterPro IPR017824
KEGG R05553
MetaCyc ADCLY-RXN
RHEA 16204

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0008149 para-aminobenzoic acid (PABA) synthase CONSIDER GO:0008696
GO:0008950 p-aminobenzoate synthetase CONSIDER GO:0008696

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008696:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008696. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008696 based on the entire annotation set Co-occurrence statistics for GO:0008696 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = p-aminobenzoate + pyruvate.
2010-10-11 Added DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate.
2010-10-11 Added XREF RHEA:16204
2010-10-11 Added XREF KEGG:R05553
2009-01-12 Deleted RELATION is a GO:0016829 (lyase activity)
2009-01-12 Added RELATION is a GO:0016833 (oxo-acid-lyase activity)
2008-05-13 Added DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = p-aminobenzoate + pyruvate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = p-aminobenzoate + pyruvate.
2008-04-01 Updated RELATION is a GO:0016829 (lyase activity)
2007-11-08 Deleted SYNONYM aminodeoxychorismate lyase
2007-11-08 Added SYNONYM 4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)
2007-11-08 Added SYNONYM aminodeoxychorismate lyase activity
2007-10-16 Deleted SYNONYM 4-amino-4-deoxychorismate lyase activity
2007-09-06 Added SYNONYM 4-amino-4-deoxychorismate lyase activity
2007-09-06 Added SYNONYM 4-amino-4-deoxychorismate pyruvate-lyase activity
2007-09-06 Added SYNONYM ADC lyase activity
2007-09-06 Added SYNONYM enzyme X activity
2007-09-06 Deleted SYNONYM ADC lyase
2007-08-09 Added SYNONYM ADC lyase
2007-08-09 Added SYNONYM aminodeoxychorismate lyase
2007-08-09 Added SYNONYM p-aminobenzoate synthetase
2007-08-09 Added SYNONYM para-aminobenzoic acid (PABA) synthase
2007-08-09 Added SYNONYM para-aminobenzoic acid synthase
2007-08-09 Deleted SYNONYM ADC lyase
2007-08-09 Deleted SYNONYM aminodeoxychorismate lyase
2007-08-09 Deleted SYNONYM p-aminobenzoate synthetase
2007-08-09 Deleted SYNONYM para-aminobenzoic acid (PABA) synthase
2007-08-09 Deleted SYNONYM para-aminobenzoic acid synthase
2005-08-10 Added SYNONYM p-aminobenzoate synthetase
2005-08-10 Added SYNONYM para-aminobenzoic acid (PABA) synthase
2005-03-10 Deleted XREF EC:4.-.-.-
2005-03-10 Added XREF EC:4.1.3.38
2005-03-10 Added SYNONYM aminodeoxychorismate lyase
2004-04-19 Added SYNONYM ADC lyase
2004-04-19 Added SYNONYM para-aminobenzoic acid synthase
2004-04-16 Deleted SYNONYM ADC lyase
2004-04-05 Deleted SYNONYM para-aminobenzoic acid synthase
2003-10-27 Added SYNONYM ADC lyase
2003-10-27 Added SYNONYM para-aminobenzoic acid synthase
2003-10-27 Added XREF MetaCyc:ADCLY-RXN
2003-03-26 Added DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = p-aminobenzoate + pyruvate.
2003-03-19 Updated TERM 4-amino-4-deoxychorismate lyase activity
2003-01-04 Added XREF EC:4.-.-.-
2002-02-06 Updated TERM 4-amino-4-deoxychorismate lyase
2001-04-03 Updated TERM 4-amino-4-deoxychorismate lyase
2001-03-30 Added TERM 4-amino-4-deoxychorismate lyase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM 4-amino-4-deoxychorismate lyase activity
2002-02-06 Updated TERM 4-amino-4-deoxychorismate lyase
2001-04-03 Updated TERM 4-amino-4-deoxychorismate lyase
2001-03-30 Added TERM 4-amino-4-deoxychorismate lyase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = p-aminobenzoate + pyruvate.
2010-10-11 Added DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate.
2008-05-13 Added DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = p-aminobenzoate + pyruvate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = p-aminobenzoate + pyruvate.
2007-11-08 Deleted SYNONYM aminodeoxychorismate lyase
2007-11-08 Added SYNONYM 4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)
2007-11-08 Added SYNONYM aminodeoxychorismate lyase activity
2007-10-16 Deleted SYNONYM 4-amino-4-deoxychorismate lyase activity
2007-09-06 Added SYNONYM 4-amino-4-deoxychorismate lyase activity
2007-09-06 Added SYNONYM 4-amino-4-deoxychorismate pyruvate-lyase activity
2007-09-06 Added SYNONYM ADC lyase activity
2007-09-06 Added SYNONYM enzyme X activity
2007-09-06 Deleted SYNONYM ADC lyase
2007-08-09 Added SYNONYM ADC lyase
2007-08-09 Added SYNONYM aminodeoxychorismate lyase
2007-08-09 Added SYNONYM p-aminobenzoate synthetase
2007-08-09 Added SYNONYM para-aminobenzoic acid (PABA) synthase
2007-08-09 Added SYNONYM para-aminobenzoic acid synthase
2007-08-09 Deleted SYNONYM ADC lyase
2007-08-09 Deleted SYNONYM aminodeoxychorismate lyase
2007-08-09 Deleted SYNONYM p-aminobenzoate synthetase
2007-08-09 Deleted SYNONYM para-aminobenzoic acid (PABA) synthase
2007-08-09 Deleted SYNONYM para-aminobenzoic acid synthase
2005-08-10 Added SYNONYM p-aminobenzoate synthetase
2005-08-10 Added SYNONYM para-aminobenzoic acid (PABA) synthase
2005-03-10 Added SYNONYM aminodeoxychorismate lyase
2004-04-19 Added SYNONYM ADC lyase
2004-04-19 Added SYNONYM para-aminobenzoic acid synthase
2004-04-16 Deleted SYNONYM ADC lyase
2004-04-05 Deleted SYNONYM para-aminobenzoic acid synthase
2003-10-27 Added SYNONYM ADC lyase
2003-10-27 Added SYNONYM para-aminobenzoic acid synthase
2003-03-26 Added DEFINITION Catalysis of the reaction: 4-amino-4-deoxychorismate = p-aminobenzoate + pyruvate.

Relationships

Timestamp Action Category Detail
2009-01-12 Deleted RELATION is a GO:0016829 (lyase activity)
2009-01-12 Added RELATION is a GO:0016833 (oxo-acid-lyase activity)
2008-04-01 Updated RELATION is a GO:0016829 (lyase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF RHEA:16204
2010-10-11 Added XREF KEGG:R05553
2005-03-10 Deleted XREF EC:4.-.-.-
2005-03-10 Added XREF EC:4.1.3.38
2003-10-27 Added XREF MetaCyc:ADCLY-RXN
2003-01-04 Added XREF EC:4.-.-.-
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