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GO:0008637 apoptotic mitochondrial changes

Term Information

ID GO:0008637
Name apoptotic mitochondrial changes
Ontology Biological Process
Definition The morphological and physiological alterations undergone by mitochondria during apoptosis.
Comment This term was created to reflect the fundamental role of the mitochondrial compartment in apoptosis. Most processes under this node occur during the signaling phase of apoptosis, but e.g. GO:0043653 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed under the signaling phase. For this reason, the parent term GO:0008637 'apoptotic mitochondrial changes' is not linked to the signaling or execution phase specifically, but its descendants are when current knowledge allows for it.
GONUTS GO:0008637 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating cell death and apoptosis using the new guidelinesLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000490 GO:0006915 apoptotic process never_in_taxon 33090 Viridiplantae
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008637:
Relationship To GO:0008637 Child Term Child Term Name
Is a GO:0043653 mitochondrial fragmentation involved in apoptotic process
Is a GO:0001836 release of cytochrome c from mitochondria
Is a GO:0032976 release of matrix enzymes from mitochondria
Is a GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008637. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008637 based on the entire annotation set Co-occurrence statistics for GO:0008637 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-03-21 Added RELATION part of GO:0006915 (apoptotic process)
2009-03-21 Deleted RELATION part of GO:0008632 (apoptotic program)
2008-05-13 Added DEFINITION The morphological and physiological alterations undergone by mitochondria during apoptosis.
2008-05-12 Deleted DEFINITION The morphological and physiological alterations undergone by mitochondria during apoptosis.
2008-04-01 Updated RELATION part of GO:0008632 (apoptotic program)
2008-04-01 Updated RELATION is a GO:0007005 (mitochondrion organization)
2004-07-25 Updated DEFINITION The morphological and physiological alterations undergone by mitochondria during apoptosis.
2002-02-06 Updated TERM apoptotic mitochondrial changes
2001-08-06 Added DEFINITION Changes to the membrane and redox state of mitochondria that are associated with the process of apoptosis.
2001-04-03 Updated TERM apoptotic mitochondrial changes
2001-03-30 Added TERM apoptotic mitochondrial changes

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM apoptotic mitochondrial changes
2001-04-03 Updated TERM apoptotic mitochondrial changes
2001-03-30 Added TERM apoptotic mitochondrial changes

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The morphological and physiological alterations undergone by mitochondria during apoptosis.
2008-05-12 Deleted DEFINITION The morphological and physiological alterations undergone by mitochondria during apoptosis.
2004-07-25 Updated DEFINITION The morphological and physiological alterations undergone by mitochondria during apoptosis.
2001-08-06 Added DEFINITION Changes to the membrane and redox state of mitochondria that are associated with the process of apoptosis.

Relationships

Timestamp Action Category Detail
2009-03-21 Added RELATION part of GO:0006915 (apoptotic process)
2009-03-21 Deleted RELATION part of GO:0008632 (apoptotic program)
2008-04-01 Updated RELATION part of GO:0008632 (apoptotic program)
2008-04-01 Updated RELATION is a GO:0007005 (mitochondrion organization)
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