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GO:0008634 negative regulation of survival gene product expression

This term is obsolete.
This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc.

Term Information

ID GO:0008634
Name negative regulation of survival gene product expression
Ontology Biological Process
Definition OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
Comment This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc.
GONUTS GO:0008634 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad down-regulation of survival gene product activity
broad downregulation of survival gene product activity
narrow inhibition of survival gene product activity
broad down regulation of survival gene product activity
broad negative regulation of survival gene products
broad negative regulation of survival gene product activity

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008634:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008634. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008634 based on the entire annotation set Co-occurrence statistics for GO:0008634 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-10-14 Updated TERM negative regulation of survival gene product expression
2012-10-14 Added DEFINITION OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2012-10-14 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2012-10-14 Deleted RELATION is a GO:0045884 (regulation of survival gene product expression)
2012-10-14 Deleted RELATION is a GO:0010629 (negative regulation of gene expression)
2012-10-14 Deleted RELATION is a GO:0043065 (positive regulation of apoptotic process)
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2009-10-07 Added RELATION is a GO:0043065 (positive regulation of apoptotic process)
2009-06-25 Added SYNONYM down-regulation of survival gene product activity
2009-06-25 Deleted SYNONYM negative regulation of survival gene product activity
2009-06-25 Deleted SYNONYM downregulation of survival gene product activity
2009-06-25 Deleted SYNONYM negative regulation of survival gene products
2009-06-25 Deleted SYNONYM down regulation of survival gene product activity
2009-06-25 Deleted SYNONYM down-regulation of survival gene product activity
2009-06-25 Added SYNONYM negative regulation of survival gene products
2009-06-25 Added SYNONYM down regulation of survival gene product activity
2009-06-25 Added SYNONYM negative regulation of survival gene product activity
2009-06-25 Added SYNONYM downregulation of survival gene product activity
2008-07-18 Added RELATION is a GO:0010629 (negative regulation of gene expression)
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2008-04-27 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2008-04-01 Updated RELATION is a GO:0045884 (regulation of survival gene product expression)
2008-03-03 Added SYNONYM negative regulation of survival gene product activity
2008-03-03 Updated TERM negative regulation of survival gene product expression
2007-08-09 Added SYNONYM negative regulation of survival gene products
2007-08-09 Added SYNONYM down regulation of survival gene product activity
2007-08-09 Added SYNONYM down-regulation of survival gene product activity
2007-08-09 Added SYNONYM downregulation of survival gene product activity
2007-08-09 Added SYNONYM inhibition of survival gene product activity
2007-08-09 Deleted SYNONYM down regulation of survival gene product activity
2007-08-09 Deleted SYNONYM down-regulation of survival gene product activity
2007-08-09 Deleted SYNONYM downregulation of survival gene product activity
2007-08-09 Deleted SYNONYM inhibition of survival gene product activity
2007-08-09 Deleted SYNONYM negative regulation of survival gene products
2007-02-23 Added SYNONYM down regulation of survival gene product activity
2007-02-23 Added SYNONYM down-regulation of survival gene product activity
2007-02-23 Added SYNONYM downregulation of survival gene product activity
2007-02-23 Added SYNONYM inhibition of survival gene product activity
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2004-04-19 Added SYNONYM negative regulation of survival gene products
2004-04-16 Deleted SYNONYM negative regulation of survival gene products
2004-01-10 Added SYNONYM negative regulation of survival gene products
2004-01-10 Updated TERM negative regulation of survival gene product activity
2003-04-25 Updated DEFINITION Any process that stops, prevents or reduces the rate of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2002-11-27 Updated DEFINITION Any process that stops, prevents or reduces the rate of survival gene product activity.
2002-07-16 Updated TERM negative regulation of survival gene products
2002-02-06 Updated TERM repression of survival gene products
2001-08-06 Added DEFINITION The repression, by transcriptional or post-transcriptional regulation, of genes that inhibit apoptosis (prosurvival genes).
2001-04-03 Updated TERM repression of survival gene products
2001-03-30 Added TERM repression of survival gene products

Term

Timestamp Action Category Detail
2012-10-14 Updated TERM negative regulation of survival gene product expression
2008-03-03 Updated TERM negative regulation of survival gene product expression
2004-01-10 Updated TERM negative regulation of survival gene product activity
2002-07-16 Updated TERM negative regulation of survival gene products
2002-02-06 Updated TERM repression of survival gene products
2001-04-03 Updated TERM repression of survival gene products
2001-03-30 Added TERM repression of survival gene products

Definition/synonyms

Timestamp Action Category Detail
2012-10-14 Added DEFINITION OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2012-10-14 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2009-06-25 Added SYNONYM down-regulation of survival gene product activity
2009-06-25 Deleted SYNONYM negative regulation of survival gene product activity
2009-06-25 Deleted SYNONYM downregulation of survival gene product activity
2009-06-25 Deleted SYNONYM negative regulation of survival gene products
2009-06-25 Deleted SYNONYM down regulation of survival gene product activity
2009-06-25 Deleted SYNONYM down-regulation of survival gene product activity
2009-06-25 Added SYNONYM negative regulation of survival gene products
2009-06-25 Added SYNONYM down regulation of survival gene product activity
2009-06-25 Added SYNONYM negative regulation of survival gene product activity
2009-06-25 Added SYNONYM downregulation of survival gene product activity
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2008-04-27 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2008-03-03 Added SYNONYM negative regulation of survival gene product activity
2007-08-09 Added SYNONYM negative regulation of survival gene products
2007-08-09 Added SYNONYM down regulation of survival gene product activity
2007-08-09 Added SYNONYM down-regulation of survival gene product activity
2007-08-09 Added SYNONYM downregulation of survival gene product activity
2007-08-09 Added SYNONYM inhibition of survival gene product activity
2007-08-09 Deleted SYNONYM down regulation of survival gene product activity
2007-08-09 Deleted SYNONYM down-regulation of survival gene product activity
2007-08-09 Deleted SYNONYM downregulation of survival gene product activity
2007-08-09 Deleted SYNONYM inhibition of survival gene product activity
2007-08-09 Deleted SYNONYM negative regulation of survival gene products
2007-02-23 Added SYNONYM down regulation of survival gene product activity
2007-02-23 Added SYNONYM down-regulation of survival gene product activity
2007-02-23 Added SYNONYM downregulation of survival gene product activity
2007-02-23 Added SYNONYM inhibition of survival gene product activity
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2004-04-19 Added SYNONYM negative regulation of survival gene products
2004-04-16 Deleted SYNONYM negative regulation of survival gene products
2004-01-10 Added SYNONYM negative regulation of survival gene products
2003-04-25 Updated DEFINITION Any process that stops, prevents or reduces the rate of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2002-11-27 Updated DEFINITION Any process that stops, prevents or reduces the rate of survival gene product activity.
2001-08-06 Added DEFINITION The repression, by transcriptional or post-transcriptional regulation, of genes that inhibit apoptosis (prosurvival genes).

Relationships

Timestamp Action Category Detail
2012-10-14 Deleted RELATION is a GO:0045884 (regulation of survival gene product expression)
2012-10-14 Deleted RELATION is a GO:0010629 (negative regulation of gene expression)
2012-10-14 Deleted RELATION is a GO:0043065 (positive regulation of apoptotic process)
2009-10-07 Added RELATION is a GO:0043065 (positive regulation of apoptotic process)
2008-07-18 Added RELATION is a GO:0010629 (negative regulation of gene expression)
2008-04-01 Updated RELATION is a GO:0045884 (regulation of survival gene product expression)
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