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GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress

Term Information

ID GO:0008627
Name intrinsic apoptotic signaling pathway in response to osmotic stress
Ontology Biological Process
Definition A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.
PMID:11454444 PMID:16483738
GONUTS GO:0008627 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related induction of apoptosis by ionic changes

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating cell death and apoptosis using the new guidelinesLink

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000490 GO:0006915 apoptotic process never_in_taxon 33090 Viridiplantae
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008627:
Relationship To GO:0008627 Child Term Child Term Name
Regulates GO:1902218 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
Negatively regulates GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
Positively regulates GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
Is a GO:1990127 intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008627. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008627 based on the entire annotation set Co-occurrence statistics for GO:0008627 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-07-27 Added RELATION is a GO:0071470 (cellular response to osmotic stress)
2013-07-27 Deleted RELATION is a GO:0006970 (response to osmotic stress)
2012-11-09 Deleted DEFINITION Any process induced by changes in intracellular ion homeostasis that directly activates any of the steps required for cell death by apoptosis.
2012-11-09 Added DEFINITION A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.
2012-09-28 Updated TERM intrinsic apoptotic signaling pathway in response to osmotic stress
2012-09-28 Added SYNONYM induction of apoptosis by ionic changes
2012-09-28 Added RELATION is a GO:0097193 (intrinsic apoptotic signaling pathway)
2012-09-28 Added RELATION is a GO:0006970 (response to osmotic stress)
2012-09-28 Deleted RELATION is a GO:0008629 (induction of apoptosis by intracellular signals)
2010-10-17 Added DEFINITION Any process induced by changes in intracellular ion homeostasis that directly activates any of the steps required for cell death by apoptosis.
2010-10-17 Added RELATION is a GO:0008629 (induction of apoptosis by intracellular signals)
2010-10-17 Deleted RELATION is a GO:0008624 (induction of apoptosis by extracellular signals)
2008-04-01 Updated RELATION is a GO:0008624 (induction of apoptosis by extracellular signals)
2002-02-06 Updated TERM induction of apoptosis by ionic changes
2001-04-03 Updated TERM induction of apoptosis by ionic changes
2001-03-30 Added TERM induction of apoptosis by ionic changes

Term

Timestamp Action Category Detail
2012-09-28 Updated TERM intrinsic apoptotic signaling pathway in response to osmotic stress
2002-02-06 Updated TERM induction of apoptosis by ionic changes
2001-04-03 Updated TERM induction of apoptosis by ionic changes
2001-03-30 Added TERM induction of apoptosis by ionic changes

Definition/synonyms

Timestamp Action Category Detail
2012-11-09 Deleted DEFINITION Any process induced by changes in intracellular ion homeostasis that directly activates any of the steps required for cell death by apoptosis.
2012-11-09 Added DEFINITION A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.
2012-09-28 Added SYNONYM induction of apoptosis by ionic changes
2010-10-17 Added DEFINITION Any process induced by changes in intracellular ion homeostasis that directly activates any of the steps required for cell death by apoptosis.

Relationships

Timestamp Action Category Detail
2013-07-27 Added RELATION is a GO:0071470 (cellular response to osmotic stress)
2013-07-27 Deleted RELATION is a GO:0006970 (response to osmotic stress)
2012-09-28 Added RELATION is a GO:0097193 (intrinsic apoptotic signaling pathway)
2012-09-28 Added RELATION is a GO:0006970 (response to osmotic stress)
2012-09-28 Deleted RELATION is a GO:0008629 (induction of apoptosis by intracellular signals)
2010-10-17 Added RELATION is a GO:0008629 (induction of apoptosis by intracellular signals)
2010-10-17 Deleted RELATION is a GO:0008624 (induction of apoptosis by extracellular signals)
2008-04-01 Updated RELATION is a GO:0008624 (induction of apoptosis by extracellular signals)
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