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GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity

Term Information

ID GO:0008467
Name [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity
Ontology Molecular Function
Definition Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
GONUTS GO:0008467 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase
related heparin-glucosamine 3-O-sulphotransferase activity
exact 3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity
related heparin-glucosamine 3-O-sulfotransferase activity
exact heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity
related isoform/isozyme 1 (3-OST-1, HS3ST1)
exact 3-OST-1 activity
exact glucosaminyl 3-O-sulfotransferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.8.2.23
MetaCyc 2.8.2.23-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008467:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008467. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008467 based on the entire annotation set Co-occurrence statistics for GO:0008467 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-09-15 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2010-09-15 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2008-08-23 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2008-08-23 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*16S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2008-06-20 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)16S GlcA GlcN2S*16S GlcA>IdoA12S Glc(N2S/NAc)16S.
2008-06-20 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*16S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2008-06-03 Updated TERM [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity
2008-06-03 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2008-06-03 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)16S GlcA GlcN2S*16S GlcA>IdoA12S Glc(N2S/NAc)16S.
2008-06-03 Deleted SYNONYM [heparan sulfate]-glucosamine 3-sulfotransferase 1
2008-06-03 Deleted SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2008-06-03 Added SYNONYM heparin-glucosamine 3-O-sulfotransferase activity
2008-06-03 Added SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2008-06-03 Added RELATION is a GO:0034483 (heparan sulfate sulfotransferase activity)
2008-06-03 Deleted RELATION is a GO:0008146 (sulfotransferase activity)
2008-05-13 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2008-04-01 Updated RELATION is a GO:0008146 (sulfotransferase activity)
2007-11-08 Added SYNONYM 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase
2007-11-08 Added SYNONYM [heparan sulfate]-glucosamine 3-sulfotransferase 1
2007-11-08 Added SYNONYM isoform/isozyme 1 (3-OST-1, HS3ST1)
2007-09-06 Added SYNONYM 3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity
2007-09-06 Added SYNONYM 3-OST-1 activity
2007-09-06 Added SYNONYM glucosaminyl 3-O-sulfotransferase activity
2007-09-06 Added SYNONYM heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity
2007-08-09 Added SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2007-08-09 Deleted SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2004-04-19 Added SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2004-04-16 Deleted SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2003-11-13 Added SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2003-10-27 Added XREF MetaCyc:2.8.2.23-RXN
2003-09-25 Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate (PAPS) + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2003-03-19 Updated TERM heparin-glucosamine 3-O-sulfotransferase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylylsulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2002-02-06 Updated TERM heparin-glucosamine 3-O-sulfotransferase
2001-04-03 Updated TERM heparin-glucosamine 3-O-sulfotransferase
2001-03-30 Added XREF EC:2.8.2.23
2001-03-30 Added TERM heparin-glucosamine 3-O-sulfotransferase

Term

Timestamp Action Category Detail
2008-06-03 Updated TERM [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity
2003-03-19 Updated TERM heparin-glucosamine 3-O-sulfotransferase activity
2002-02-06 Updated TERM heparin-glucosamine 3-O-sulfotransferase
2001-04-03 Updated TERM heparin-glucosamine 3-O-sulfotransferase
2001-03-30 Added TERM heparin-glucosamine 3-O-sulfotransferase

Definition/synonyms

Timestamp Action Category Detail
2010-09-15 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2010-09-15 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2008-08-23 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2008-08-23 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*16S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2008-06-20 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)16S GlcA GlcN2S*16S GlcA>IdoA12S Glc(N2S/NAc)16S.
2008-06-20 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*16S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
2008-06-03 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2008-06-03 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)16S GlcA GlcN2S*16S GlcA>IdoA12S Glc(N2S/NAc)16S.
2008-06-03 Deleted SYNONYM [heparan sulfate]-glucosamine 3-sulfotransferase 1
2008-06-03 Deleted SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2008-06-03 Added SYNONYM heparin-glucosamine 3-O-sulfotransferase activity
2008-06-03 Added SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2007-11-08 Added SYNONYM 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase
2007-11-08 Added SYNONYM [heparan sulfate]-glucosamine 3-sulfotransferase 1
2007-11-08 Added SYNONYM isoform/isozyme 1 (3-OST-1, HS3ST1)
2007-09-06 Added SYNONYM 3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity
2007-09-06 Added SYNONYM 3-OST-1 activity
2007-09-06 Added SYNONYM glucosaminyl 3-O-sulfotransferase activity
2007-09-06 Added SYNONYM heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity
2007-08-09 Added SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2007-08-09 Deleted SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2004-04-19 Added SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2004-04-16 Deleted SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2003-11-13 Added SYNONYM heparin-glucosamine 3-O-sulphotransferase activity
2003-09-25 Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate (PAPS) + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2002-11-27 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylylsulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.

Relationships

Timestamp Action Category Detail
2008-06-03 Added RELATION is a GO:0034483 (heparan sulfate sulfotransferase activity)
2008-06-03 Deleted RELATION is a GO:0008146 (sulfotransferase activity)
2008-04-01 Updated RELATION is a GO:0008146 (sulfotransferase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:2.8.2.23-RXN
2001-03-30 Added XREF EC:2.8.2.23
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