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GO:0008423 bleomycin hydrolase activity

This term is obsolete.
This term was made obsolete because it represents a gene product.

Term Information

ID GO:0008423
Name bleomycin hydrolase activity
Ontology Molecular Function
Definition OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
Comment This term was made obsolete because it represents a gene product.
GONUTS GO:0008423 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow aminopeptidase C (Lactococcus lactis)

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Replaced by GO:0004197 Molecular Function cysteine-type endopeptidase activity

Cross-references

Database ID
EC 3.4.22.40
MetaCyc 3.4.22.40-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008423:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008423. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008423 based on the entire annotation set Co-occurrence statistics for GO:0008423 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2010-06-08 Updated TERM bleomycin hydrolase activity
2008-11-08 Added OBSOLETION replaced_by GO:0004197 (cysteine-type endopeptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0004197 (cysteine-type endopeptidase activity)
2008-08-18 Deleted DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2008-08-18 Added DEFINITION OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2008-08-18 Deleted RELATION is a GO:0004197 (cysteine-type endopeptidase activity)
2008-08-18 Added RELATION is a GO:0008369 (obsolete molecular function)
2008-08-18 Added OBSOLETION replaced_by GO:0004197 (cysteine-type endopeptidase activity)
2008-05-13 Added DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2008-05-12 Deleted DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2008-04-01 Updated RELATION is a GO:0004197 (cysteine-type endopeptidase activity)
2007-09-06 Added SYNONYM aminopeptidase C (Lactococcus lactis)
2003-10-27 Added XREF MetaCyc:3.4.22.40-RXN
2003-03-19 Updated TERM bleomycin hydrolase activity
2002-11-27 Added DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2002-02-06 Updated TERM bleomycin hydrolase
2001-04-03 Updated TERM bleomycin hydrolase
2001-03-30 Added XREF EC:3.4.22.40
2001-03-30 Added TERM bleomycin hydrolase

Term

Timestamp Action Category Detail
2010-06-08 Updated TERM bleomycin hydrolase activity
2003-03-19 Updated TERM bleomycin hydrolase activity
2002-02-06 Updated TERM bleomycin hydrolase
2001-04-03 Updated TERM bleomycin hydrolase
2001-03-30 Added TERM bleomycin hydrolase

Obsoletions

Timestamp Action Category Detail
2008-11-08 Added OBSOLETION replaced_by GO:0004197 (cysteine-type endopeptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0004197 (cysteine-type endopeptidase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0004197 (cysteine-type endopeptidase activity)

Definition/synonyms

Timestamp Action Category Detail
2008-08-18 Deleted DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2008-08-18 Added DEFINITION OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2008-05-13 Added DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2008-05-12 Deleted DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2007-09-06 Added SYNONYM aminopeptidase C (Lactococcus lactis)
2002-11-27 Added DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.

Relationships

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2008-08-18 Deleted RELATION is a GO:0004197 (cysteine-type endopeptidase activity)
2008-08-18 Added RELATION is a GO:0008369 (obsolete molecular function)
2008-04-01 Updated RELATION is a GO:0004197 (cysteine-type endopeptidase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:3.4.22.40-RXN
2001-03-30 Added XREF EC:3.4.22.40
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