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GO:0008403 25-hydroxycholecalciferol-24-hydroxylase activity

Term Information

ID GO:0008403
Name 25-hydroxycholecalciferol-24-hydroxylase activity
Ontology Molecular Function
Definition Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.
Secondary IDs GO:0030344
GONUTS GO:0008403 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow cytochrome P450 CYP24
exact 25-hydroxyvitamin D3 24-hydroxylase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008403:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008403. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008403 based on the entire annotation set Co-occurrence statistics for GO:0008403 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-05-21 Added RELATION is a GO:0070576 (vitamin D 24-hydroxylase activity)
2009-04-29 Deleted DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycalciferol.
2009-04-29 Added DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.
2008-05-13 Added DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycalciferol.
2008-05-12 Deleted DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycalciferol.
2008-04-01 Updated RELATION is a GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
2008-04-01 Updated RELATION is a GO:0004497 (monooxygenase activity)
2007-08-09 Added SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2007-08-09 Added SYNONYM cytochrome P450 CYP24
2007-08-09 Deleted SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2007-08-09 Deleted SYNONYM cytochrome P450 CYP24
2004-07-29 Added DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycalciferol.
2004-04-19 Added SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2004-04-19 Added SYNONYM cytochrome P450 CYP24
2004-04-16 Deleted SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2004-04-16 Deleted SYNONYM cytochrome P450 CYP24
2003-09-20 Added SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2003-09-20 Added SECONDARY GO:0030344 (25-hydroxyvitamin D3 24-hydroxylase activity)
2003-03-19 Updated TERM 25-hydroxycholecalciferol-24-hydroxylase activity
2002-02-06 Updated TERM 25-hydroxycholecalciferol-24-hydroxylase
2001-04-03 Updated TERM 25-hydroxycholecalciferol-24-hydroxylase
2001-03-30 Added SYNONYM cytochrome P450 CYP24
2001-03-30 Added TERM 25-hydroxycholecalciferol-24-hydroxylase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM 25-hydroxycholecalciferol-24-hydroxylase activity
2002-02-06 Updated TERM 25-hydroxycholecalciferol-24-hydroxylase
2001-04-03 Updated TERM 25-hydroxycholecalciferol-24-hydroxylase
2001-03-30 Added TERM 25-hydroxycholecalciferol-24-hydroxylase

Definition/synonyms

Timestamp Action Category Detail
2009-04-29 Deleted DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycalciferol.
2009-04-29 Added DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.
2008-05-13 Added DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycalciferol.
2008-05-12 Deleted DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycalciferol.
2007-08-09 Added SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2007-08-09 Added SYNONYM cytochrome P450 CYP24
2007-08-09 Deleted SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2007-08-09 Deleted SYNONYM cytochrome P450 CYP24
2004-07-29 Added DEFINITION Catalysis of the hydroxylation of C-24 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycalciferol.
2004-04-19 Added SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2004-04-19 Added SYNONYM cytochrome P450 CYP24
2004-04-16 Deleted SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2004-04-16 Deleted SYNONYM cytochrome P450 CYP24
2003-09-20 Added SYNONYM 25-hydroxyvitamin D3 24-hydroxylase activity
2001-03-30 Added SYNONYM cytochrome P450 CYP24

Relationships

Timestamp Action Category Detail
2009-05-21 Added RELATION is a GO:0070576 (vitamin D 24-hydroxylase activity)
2008-04-01 Updated RELATION is a GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
2008-04-01 Updated RELATION is a GO:0004497 (monooxygenase activity)

Other

Timestamp Action Category Detail
2003-09-20 Added SECONDARY GO:0030344 (25-hydroxyvitamin D3 24-hydroxylase activity)
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