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GO:0008329 signaling pattern recognition receptor activity

Term Information

ID GO:0008329
Name signaling pattern recognition receptor activity
Ontology Molecular Function
Definition Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
PMID:12507420 PMID:12925128 PMID:14523544
Comment This term and its child terms are intended for gene products which are directly coupled to a signal transduction pathway. For pattern recognition receptors which do not relay an intracellular signal (e.g. endocytic pattern recognition receptors), consider instead annotating to 'pattern recognition receptor activity ; GO:0038187' and/or the child terms of 'pattern binding ; GO:0001871'. Note that many gene products that are called pattern recognition receptors in the literature have a broad range of potential ligands and also can be annotated to 'scavenger receptor activity ; GO:0005044'.
GONUTS GO:0008329 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related macrophage receptor activity
exact signaling PRR activity

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0008019 macrophage receptor activity CONSIDER GO:0008329

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008329:
Relationship To GO:0008329 Child Term Child Term Name
Is a GO:0016019 peptidoglycan receptor activity
Is a GO:0001873 polysaccharide receptor activity
Is a GO:0001875 lipopolysaccharide receptor activity
Is a GO:0001877 lipoarabinomannan receptor activity
Is a GO:0070892 lipoteichoic acid receptor activity

Protein Annotation

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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008329. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008329 based on the entire annotation set Co-occurrence statistics for GO:0008329 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-06-12 Added DEFINITION Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
2013-06-12 Deleted DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, and transmitting the signal within the cell to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2013-05-31 Updated TERM signaling pattern recognition receptor activity
2013-05-31 Deleted DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2013-05-31 Added DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, and transmitting the signal within the cell to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2013-05-31 Added SYNONYM signaling PRR activity
2013-05-31 Added RELATION is a GO:0038187 (pattern recognition receptor activity)
2012-10-29 Deleted RELATION is a GO:0004872 (receptor activity)
2012-10-29 Added RELATION is a GO:0038023 (signaling receptor activity)
2012-02-09 Deleted RELATION is a GO:0038023 (signaling receptor activity)
2011-08-04 Added RELATION is a GO:0038023 (signaling receptor activity)
2010-06-15 Added RELATION part of GO:0002221 (pattern recognition receptor signaling pathway)
2010-06-14 Deleted RELATION part of GO:0002221 (pattern recognition receptor signaling pathway)
2010-06-08 Added RELATION part of GO:0002221 (pattern recognition receptor signaling pathway)
2008-05-13 Added DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2008-05-12 Deleted DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2008-04-01 Updated RELATION is a GO:0004872 (receptor activity)
2007-08-09 Added SYNONYM macrophage receptor activity
2007-08-09 Deleted SYNONYM macrophage receptor activity
2005-08-10 Added SYNONYM macrophage receptor activity
2004-07-07 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-07-03 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-06-25 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-05-30 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-05-29 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-05-02 Added DEFINITION Combining with pathogen-associated molecular patterns to initiate a change in cell activity. Pathogen-associated molecular patterns are conserved molecular structures found in large groups of pathogens.
2003-03-19 Updated TERM pattern recognition receptor activity
2002-02-06 Updated TERM pattern recognition receptor
2001-04-03 Updated TERM pattern recognition receptor
2001-03-30 Added TERM pattern recognition receptor

Term

Timestamp Action Category Detail
2013-05-31 Updated TERM signaling pattern recognition receptor activity
2003-03-19 Updated TERM pattern recognition receptor activity
2002-02-06 Updated TERM pattern recognition receptor
2001-04-03 Updated TERM pattern recognition receptor
2001-03-30 Added TERM pattern recognition receptor

Definition/synonyms

Timestamp Action Category Detail
2013-06-12 Added DEFINITION Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
2013-06-12 Deleted DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, and transmitting the signal within the cell to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2013-05-31 Deleted DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2013-05-31 Added DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, and transmitting the signal within the cell to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2013-05-31 Added SYNONYM signaling PRR activity
2008-05-13 Added DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2008-05-12 Deleted DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2007-08-09 Added SYNONYM macrophage receptor activity
2007-08-09 Deleted SYNONYM macrophage receptor activity
2005-08-10 Added SYNONYM macrophage receptor activity
2004-07-07 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-07-03 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-06-25 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-05-30 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-05-29 Updated DEFINITION Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens.
2004-05-02 Added DEFINITION Combining with pathogen-associated molecular patterns to initiate a change in cell activity. Pathogen-associated molecular patterns are conserved molecular structures found in large groups of pathogens.

Relationships

Timestamp Action Category Detail
2013-05-31 Added RELATION is a GO:0038187 (pattern recognition receptor activity)
2012-10-29 Deleted RELATION is a GO:0004872 (receptor activity)
2012-10-29 Added RELATION is a GO:0038023 (signaling receptor activity)
2012-02-09 Deleted RELATION is a GO:0038023 (signaling receptor activity)
2011-08-04 Added RELATION is a GO:0038023 (signaling receptor activity)
2010-06-15 Added RELATION part of GO:0002221 (pattern recognition receptor signaling pathway)
2010-06-14 Deleted RELATION part of GO:0002221 (pattern recognition receptor signaling pathway)
2010-06-08 Added RELATION part of GO:0002221 (pattern recognition receptor signaling pathway)
2008-04-01 Updated RELATION is a GO:0004872 (receptor activity)
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