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GO:0008305 integrin complex

Term Information

ID GO:0008305
Name integrin complex
Ontology Cellular Component
Definition A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
PMID:17543136
GONUTS GO:0008305 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related laminin receptor protein

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR000413
InterPro IPR012013
InterPro IPR015436
InterPro IPR015437
InterPro IPR015439
InterPro IPR015442
InterPro IPR027067
InterPro IPR027068
InterPro IPR027071

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0005613 laminin receptor protein CONSIDER GO:0008305

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008305:
Relationship To GO:0008305 Child Term Child Term Name
Is a GO:0034665 integrin alpha1-beta1 complex
Is a GO:0034666 integrin alpha2-beta1 complex
Is a GO:0034667 integrin alpha3-beta1 complex
Is a GO:0034668 integrin alpha4-beta1 complex
Is a GO:0034669 integrin alpha4-beta7 complex
Is a GO:0034674 integrin alpha5-beta1 complex
Is a GO:0034675 integrin alpha6-beta1 complex
Is a GO:0034676 integrin alpha6-beta4 complex
Is a GO:0034677 integrin alpha7-beta1 complex
Is a GO:0034678 integrin alpha8-beta1 complex
Is a GO:0034679 integrin alpha9-beta1 complex
Is a GO:0034680 integrin alpha10-beta1 complex
Is a GO:0034681 integrin alpha11-beta1 complex
Is a GO:0034682 integrin alphav-beta1 complex
Is a GO:0034683 integrin alphav-beta3 complex
Is a GO:0034684 integrin alphav-beta5 complex
Is a GO:0034685 integrin alphav-beta6 complex
Is a GO:0034686 integrin alphav-beta8 complex
Is a GO:0034687 integrin alphaL-beta2 complex
Is a GO:0034688 integrin alphaM-beta2 complex
Is a GO:0034689 integrin alphaX-beta2 complex
Is a GO:0034690 integrin alphaD-beta2 complex
Is a GO:0034691 integrin alphaE-beta7 complex
Is a GO:0070442 integrin alphaIIb-beta3 complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008305. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008305 based on the entire annotation set Co-occurrence statistics for GO:0008305 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-06-05 Added RELATION is a GO:0043234 (protein complex)
2014-05-11 Added RELATION is a GO:0098636 (protein complex involved in cell adhesion)
2008-08-22 Deleted DEFINITION Any member of a family of heterodimeric transmembrane receptors for cell-adhesion molecules. The alpha and beta subunits are noncovalently bonded.
2008-08-22 Added DEFINITION A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
2008-05-13 Added DEFINITION Any member of a family of heterodimeric transmembrane receptors for cell-adhesion molecules. The alpha and beta subunits are noncovalently bonded.
2008-05-12 Deleted DEFINITION Any member of a family of heterodimeric transmembrane receptors for cell-adhesion molecules. The alpha and beta subunits are noncovalently bonded.
2008-04-01 Updated RELATION part of GO:0005887 (integral component of plasma membrane)
2008-04-01 Updated RELATION is a GO:0043235 (receptor complex)
2008-04-01 Updated RELATION is a GO:0044459 (plasma membrane part)
2007-08-09 Added SYNONYM laminin receptor protein
2007-08-09 Deleted SYNONYM laminin receptor protein
2005-08-10 Added SYNONYM laminin receptor protein
2002-11-27 Added DEFINITION Any member of a family of heterodimeric transmembrane receptors for cell-adhesion molecules. The alpha and beta subunits are noncovalently bonded.
2002-11-22 Updated TERM integrin complex
2002-02-06 Updated TERM integrin
2001-04-03 Updated TERM integrin
2001-03-30 Added TERM integrin

Term

Timestamp Action Category Detail
2002-11-22 Updated TERM integrin complex
2002-02-06 Updated TERM integrin
2001-04-03 Updated TERM integrin
2001-03-30 Added TERM integrin

Definition/synonyms

Timestamp Action Category Detail
2008-08-22 Deleted DEFINITION Any member of a family of heterodimeric transmembrane receptors for cell-adhesion molecules. The alpha and beta subunits are noncovalently bonded.
2008-08-22 Added DEFINITION A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
2008-05-13 Added DEFINITION Any member of a family of heterodimeric transmembrane receptors for cell-adhesion molecules. The alpha and beta subunits are noncovalently bonded.
2008-05-12 Deleted DEFINITION Any member of a family of heterodimeric transmembrane receptors for cell-adhesion molecules. The alpha and beta subunits are noncovalently bonded.
2007-08-09 Added SYNONYM laminin receptor protein
2007-08-09 Deleted SYNONYM laminin receptor protein
2005-08-10 Added SYNONYM laminin receptor protein
2002-11-27 Added DEFINITION Any member of a family of heterodimeric transmembrane receptors for cell-adhesion molecules. The alpha and beta subunits are noncovalently bonded.

Relationships

Timestamp Action Category Detail
2014-06-05 Added RELATION is a GO:0043234 (protein complex)
2014-05-11 Added RELATION is a GO:0098636 (protein complex involved in cell adhesion)
2008-04-01 Updated RELATION part of GO:0005887 (integral component of plasma membrane)
2008-04-01 Updated RELATION is a GO:0043235 (receptor complex)
2008-04-01 Updated RELATION is a GO:0044459 (plasma membrane part)
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