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GO:0008237 metallopeptidase activityCatalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Term Information
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| Type | Synonym |
| exact | metalloprotease activity |
| exact | metalloproteinase activity |
| Database | ID |
| INTERPRO | IPR013277 |
| INTERPRO | IPR001548 |
| INTERPRO | IPR001261 |
| INTERPRO | IPR008753 |
| INTERPRO | IPR014782 |
| INTERPRO | IPR013273 |
| INTERPRO | IPR013274 |
| INTERPRO | IPR013275 |
| INTERPRO | IPR013276 |
| INTERPRO | IPR012962 |
| INTERPRO | IPR013647 |
| INTERPRO | IPR012091 |
| INTERPRO | IPR015211 |
| INTERPRO | IPR013578 |
| INTERPRO | IPR006025 |
| INTERPRO | IPR006026 |
| INTERPRO | IPR002933 |
| INTERPRO | IPR000755 |
| INTERPRO | IPR005075 |
GO:0004246 peptidyl-dipeptidase A activity |
(replaced_by GO:0008237) |
GO:0016921 pyroglutamyl-peptidase II activity |
(replaced_by GO:0008237) |
GO:0017092 sterol regulatory element-binding protein site 2 protease activity |
(replaced_by GO:0008237) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||
![]() | GO:0003824 catalytic activity | ||||
![]() | ![]() | GO:0016787 hydrolase activity | |||
![]() | ![]() | ![]() | GO:0008233 peptidase activity | ||
![]() | ![]() | ![]() | ![]() | GO:0070011 peptidase activity, acting on L-amino acid peptides | |
![]() | ![]() | ![]() | ![]() | ![]() | GO:0008237 metallopeptidase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0004222 metalloendopeptidase activity |
| I | GO:0008235 metalloexopeptidase activity |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-20-04-03-08 |