spacer
spacer

GO:0008236 serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

Term Information

ID GO:0008236
Name serine-type peptidase activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Comment

Synonyms

Type Synonym
exact serine protease activity

Cross-references associated with this term:

Database ID
INTERPRO IPR008758
INTERPRO IPR005320
INTERPRO IPR001375
INTERPRO IPR004236
INTERPRO IPR004447
INTERPRO IPR012393
INTERPRO IPR005151
INTERPRO IPR015366
INTERPRO IPR000126
INTERPRO IPR004109
INTERPRO IPR000223
INTERPRO IPR008256

This term can be used instead of these obsolete terms:

GO:0004274 dipeptidyl-peptidase IV activity (replaced_by GO:0008236)
GO:0017094 sterol regulatory element-binding protein site 1 protease activity (replaced_by GO:0008236)
GO:0043859 cyanophycinase activity (replaced_by GO:0008236)

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0008233 peptidase activity
GO:0017171 serine hydrolase activity
GO:0070011 peptidase activity, acting on L-amino acid peptides
GO:0008236 serine-type peptidase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0008240 tripeptidyl-peptidase activity
I GO:0004252 serine-type endopeptidase activity
I GO:0070008 serine-type exopeptidase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
spacer
16ms
spacer