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GO:0008233 peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

Term Information

ID GO:0008233
Name peptidase activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
Comment

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_candida91
goslim_generic127
goslim_pir469
goslim_yeast93

Synonyms

Type Synonym
exact proteinase activity
exact hydrolase, acting on peptide bonds
exact protease activity
exact peptide hydrolase activity

Cross-references associated with this term:

Database ID
EC 3.4
INTERPRO IPR005536
INTERPRO IPR011813
INTERPRO IPR011816
INTERPRO IPR015956
INTERPRO IPR007544
INTERPRO IPR007280
INTERPRO IPR008757
INTERPRO IPR001733
INTERPRO IPR009542
INTERPRO IPR009582
INTERPRO IPR004634
INTERPRO IPR004635
INTERPRO IPR001767
INTERPRO IPR009655
INTERPRO IPR000671
INTERPRO IPR007653
INTERPRO IPR002142
INTERPRO IPR005074
INTERPRO IPR005314
INTERPRO IPR007484
INTERPRO IPR000395
INTERPRO IPR001539
INTERPRO IPR004411
INTERPRO IPR004420
INTERPRO IPR010200
INTERPRO IPR000081
INTERPRO IPR003709
INTERPRO IPR002527
INTERPRO IPR005080
INTERPRO IPR010909

This term can be used instead of these obsolete terms:

GO:0004299 proteasome endopeptidase activity (consider GO:0008233)
GO:0009003 signal peptidase activity (replaced_by GO:0008233)
GO:0031368 Pro-X metallocarboxypeptidase activity (replaced_by GO:0008233)

Web service: term information

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0008233 peptidase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0070122 isopeptidase activity
I GO:0070010 peptidase activity, acting on D-amino acid peptides
I GO:0070011 peptidase activity, acting on L-amino acid peptides
I GO:0070012 oligopeptidase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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