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GO:0008191 metalloendopeptidase inhibitor activity

Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.

Term Information

ID GO:0008191
Name metalloendopeptidase inhibitor activity
Ontology Molecular Function
Definition Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.
Comment

Synonyms

Type Synonym
broad metalloprotease inhibitor
broad metalloproteinase inhibitor

Cross-references associated with this term:

Database ID
INTERPRO IPR001820
INTERPRO IPR004231

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Ancestor Chart

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Ancestor Table

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GO:0003674 molecular_function
GO:0030234 enzyme regulator activity
GO:0004857 enzyme inhibitor activity
GO:0010576 metalloenzyme regulator activity
GO:0030414 peptidase inhibitor activity
GO:0004866 endopeptidase inhibitor activity
GO:0048551 metalloenzyme inhibitor activity
GO:0008191 metalloendopeptidase inhibitor activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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