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GO:0008168 methyltransferase activity

Term Information

ID GO:0008168
Name methyltransferase activity
Ontology Molecular Function
Definition Catalysis of the transfer of a methyl group to an acceptor molecule.
Secondary IDs GO:0004480
GONUTS GO:0008168 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad methylase

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_generic149
goslim_yeast169

Cross-references

Database ID
EC 2.1.1
InterPro IPR000692
InterPro IPR000878
InterPro IPR000940
InterPro IPR001525
InterPro IPR001555
InterPro IPR001678
InterPro IPR002052
InterPro IPR002296
InterPro IPR002877
InterPro IPR002903
InterPro IPR003043
InterPro IPR003742
InterPro IPR004026
InterPro IPR004033
InterPro IPR004159
InterPro IPR004398
InterPro IPR005299
InterPro IPR005304
InterPro IPR005885
InterPro IPR006360
InterPro IPR006363
InterPro IPR006366
InterPro IPR006700
InterPro IPR007072
InterPro IPR007213
InterPro IPR007757
InterPro IPR007823
InterPro IPR007848
InterPro IPR007857
InterPro IPR007871
InterPro IPR008031
InterPro IPR008189
InterPro IPR008576
InterPro IPR009466
InterPro IPR010286
InterPro IPR010426
InterPro IPR010675
InterPro IPR011224
InterPro IPR011610
InterPro IPR011671
InterPro IPR012653
InterPro IPR012740
InterPro IPR012920
InterPro IPR013123
InterPro IPR013216
InterPro IPR013705
InterPro IPR014122
InterPro IPR014644
InterPro IPR014776
InterPro IPR014777
InterPro IPR015095
InterPro IPR015324
InterPro IPR015507
InterPro IPR016051
InterPro IPR016218
InterPro IPR016461
InterPro IPR016479
InterPro IPR016651
InterPro IPR016653
InterPro IPR016691
InterPro IPR016718
InterPro IPR016764
InterPro IPR016914
InterPro IPR017182
InterPro IPR017610
InterPro IPR018063
InterPro IPR018314
InterPro IPR019012
InterPro IPR019614
InterPro IPR019874
InterPro IPR020813
InterPro IPR021002
InterPro IPR021721
InterPro IPR022184
InterPro IPR023032
InterPro IPR023273
InterPro IPR023397
InterPro IPR023427
InterPro IPR023467
InterPro IPR023475
InterPro IPR023503
InterPro IPR023553
InterPro IPR023576
InterPro IPR024160
InterPro IPR025779
InterPro IPR025799
InterPro IPR026635
InterPro IPR027034
InterPro IPR030384
UniProtKB-KW Methyltransferase

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008168:
Relationship To GO:0008168 Child Term Child Term Name
Is a GO:0051749 indole acetic acid carboxyl methyltransferase activity
Is a GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
Is a GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
Is a GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity
Is a GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity
Is a GO:0042086 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity
Is a GO:0004047 aminomethyltransferase activity
Is a GO:0018707 1-phenanthrol methyltransferase activity
Is a GO:0044683 methylthiol:coenzyme M methyltransferase activity
Is a GO:0008169 C-methyltransferase activity
Is a GO:0008170 N-methyltransferase activity
Is a GO:0008171 O-methyltransferase activity
Is a GO:0008172 S-methyltransferase activity
Is a GO:0008276 protein methyltransferase activity
Is a GO:0047151 methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity
Is a GO:0047152 methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity
Is a GO:0050631 corydaline synthase activity
Is a GO:0008173 RNA methyltransferase activity
Is a GO:0009008 DNA-methyltransferase activity
Is a GO:0035049 juvenile hormone acid methyltransferase activity
Is a GO:0043851 methanol-specific methylcobalamin:coenzyme M methyltransferase activity
Is a GO:0043852 monomethylamine methyltransferase activity
Is a GO:0051995 Se-methyltransferase activity
Is a GO:0043770 demethylmenaquinone methyltransferase activity
Is a GO:0043776 cobalt-precorrin-6B C5-methyltransferase activity
Is a GO:0043777 cobalt-precorrin-7 C15-methyltransferase activity
Is a GO:0043780 cobalt-precorrin-5B C1-methyltransferase activity
Is a GO:0043781 cobalt-factor II C20-methyltransferase activity
Is a GO:0043782 cobalt-precorrin-3 C17-methyltransferase activity
Is a GO:0043791 dimethylamine methyltransferase activity
Is a GO:0051994 P-methyltransferase activity
Is a GO:0043819 precorrin-6A synthase (deacetylating) activity
Is a GO:0043833 methylamine-specific methylcobalamin:coenzyme M methyltransferase activity
Is a GO:0043834 trimethylamine methyltransferase activity
Is a GO:0034931 1-hydroxypyrene methyltransferase activity
Is a GO:0034933 1-hydroxy-6-methoxypyrene methyltransferase activity
Is a GO:0034541 dimethylarsinite methyltransferase activity
Is a GO:0034807 4,5-dihydroxybenzo(a)pyrene methyltransferase activity
Is a GO:0043803 hydroxyneurosporene-O-methyltransferase activity
Is a GO:0098603 selenol Se-methyltransferase activity
Is a GO:0098613 methaneselenol methyltransferase activity
Is a GO:0098614 hydrogen selenide methyltransferase activity
Is a GO:0098615 dimethyl selenide methyltransferase activity
Is a GO:1990088 [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
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GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008168. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008168 based on the entire annotation set Co-occurrence statistics for GO:0008168 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_generic
2012-02-10 Added SLIM goslim_generic
2011-08-14 Added SLIM goslim_yeast
2010-07-16 Added RELATION part of GO:0032259 (methylation)
2008-05-13 Added DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule.
2008-04-01 Updated RELATION is a GO:0016741 (transferase activity, transferring one-carbon groups)
2007-08-09 Added SYNONYM methylase
2007-08-09 Deleted SYNONYM methylase
2006-02-09 Added XREF EC:2.1.1
2006-02-09 Deleted XREF EC:2.1.1.-
2005-05-01 Added SYNONYM methylase
2003-06-17 Updated DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule.
2003-03-26 Added DEFINITION Catalysis of a methyl group on to an acceptor molecule.
2003-03-19 Updated TERM methyltransferase activity
2002-02-06 Updated TERM methyltransferase
2001-05-16 Added SECONDARY GO:0004480 (methyl transferase)
2001-04-03 Updated TERM methyltransferase
2001-03-30 Added XREF EC:2.1.1.-
2001-03-30 Added TERM methyltransferase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM methyltransferase activity
2002-02-06 Updated TERM methyltransferase
2001-04-03 Updated TERM methyltransferase
2001-03-30 Added TERM methyltransferase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule.
2007-08-09 Added SYNONYM methylase
2007-08-09 Deleted SYNONYM methylase
2005-05-01 Added SYNONYM methylase
2003-06-17 Updated DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule.
2003-03-26 Added DEFINITION Catalysis of a methyl group on to an acceptor molecule.

Relationships

Timestamp Action Category Detail
2010-07-16 Added RELATION part of GO:0032259 (methylation)
2008-04-01 Updated RELATION is a GO:0016741 (transferase activity, transferring one-carbon groups)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:2.1.1
2006-02-09 Deleted XREF EC:2.1.1.-
2001-03-30 Added XREF EC:2.1.1.-

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_generic
2012-02-10 Added SLIM goslim_generic
2011-08-14 Added SLIM goslim_yeast
2001-05-16 Added SECONDARY GO:0004480 (methyl transferase)
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