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GO:0008123 cholesterol 7-alpha-monooxygenase activityCatalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O.
Term Information
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| Type | Synonym |
| exact | cholesterol 7alpha-monooxygenase activity |
| exact | cholesterol 7-alpha-hydroxylase activity |
| narrow | cytochrome P450 CYP7A1 |
| exact | cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) |
| exact | cholesterol 7alpha-hydroxylase activity |
| Database | ID |
| MetaCyc | CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN |
| EC | 1.14.13.17 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||||
![]() | GO:0003824 catalytic activity | ||||||
![]() | ![]() | GO:0016491 oxidoreductase activity | |||||
![]() | ![]() | ![]() | GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | ||||
![]() | ![]() | ![]() | ![]() | GO:0004497 monooxygenase activity | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0008395 steroid hydroxylase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0008123 cholesterol 7-alpha-monooxygenase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-23-04-03-36 |