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GO:0008119 thiopurine S-methyltransferase activityCatalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.
Term Information
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| Type | Synonym |
| exact | 6-thiopurine transmethylase activity |
| exact | S-adenosyl-L-methionine:thiopurine S-methyltransferase activity |
| related | TPMT |
| exact | mercaptopurine methyltransferase activity |
| exact | thiopurine methyltransferase activity |
| Database | ID |
| INTERPRO | IPR008854 |
| EC | 2.1.1.67 |
| MetaCyc | THIOPURINE-S-METHYLTRANSFERASE-RXN |
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| GO:0003674 molecular_function | |||||||
![]() | GO:0003824 catalytic activity | ||||||
![]() | ![]() | GO:0016740 transferase activity | |||||
![]() | ![]() | ![]() | GO:0016741 transferase activity, transferring one-carbon groups | ||||
![]() | ![]() | ![]() | ![]() | GO:0008168 methyltransferase activity | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0008172 S-methyltransferase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0008757 S-adenosylmethionine-dependent methyltransferase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0008119 thiopurine S-methyltransferase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |