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GO:0008081 phosphoric diester hydrolase activity

Term Information

ID GO:0008081
Name phosphoric diester hydrolase activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
Secondary IDs GO:0004434 GO:0016792
GONUTS GO:0008081 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow inositol or phosphatidylinositol phosphodiesterase activity
related endonuclease VIII activity
narrow phosphodiesterase
narrow inositol/phosphatidylinositol phosphodiesterase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.1.4
InterPro IPR010347
InterPro IPR017693
InterPro IPR017766
InterPro IPR017946
InterPro IPR023088
InterPro IPR023174
InterPro IPR024225

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0008845 endonuclease VIII activity CONSIDER GO:0008081

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008081:
Relationship To GO:0008081 Child Term Child Term Name
Is a GO:0004112 cyclic-nucleotide phosphodiesterase activity
Is a GO:0004629 phospholipase C activity
Is a GO:0004630 phospholipase D activity
Is a GO:0004528 phosphodiesterase I activity
Is a GO:0044688 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity
Is a GO:0050290 sphingomyelin phosphodiesterase D activity
Is a GO:0047387 serine-ethanolaminephosphate phosphodiesterase activity
Is a GO:0047388 adenylyl-[glutamate-ammonia ligase] hydrolase activity
Is a GO:0047389 glycerophosphocholine phosphodiesterase activity
Is a GO:0047390 glycerophosphocholine cholinephosphodiesterase activity
Is a GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity
Is a GO:0047392 CMP-N-acylneuraminate phosphodiesterase activity
Is a GO:0047393 glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity
Is a GO:0047394 glycerophosphoinositol inositolphosphodiesterase activity
Is a GO:0047395 glycerophosphoinositol glycerophosphodiesterase activity
Is a GO:0047397 dolichylphosphate-glucose phosphodiesterase activity
Is a GO:0047398 dolichylphosphate-mannose phosphodiesterase activity
Is a GO:0047399 glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity
Is a GO:0008770 [acyl-carrier-protein] phosphodiesterase activity
Is a GO:0008889 glycerophosphodiester phosphodiesterase activity
Is a GO:0004767 sphingomyelin phosphodiesterase activity
Is a GO:0070259 tyrosyl-DNA phosphodiesterase activity
Is a GO:0071111 cyclic-guanylate-specific phosphodiesterase activity
Is a GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity
Is a GO:0035755 cardiolipin hydrolase activity
Is a GO:0044603 protein adenylylhydrolase activity
Is a GO:0036317 tyrosyl-RNA phosphodiesterase activity
Is a GO:0090580 phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Date
Assigned By
Product Form ID
Name
Synonym
Type
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008081. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008081 based on the entire annotation set Co-occurrence statistics for GO:0008081 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-05-03 Deleted XREF EC:3.1.4.-
2010-10-07 Added SYNONYM inositol or phosphatidylinositol phosphodiesterase activity
2010-10-07 Added SYNONYM inositol/phosphatidylinositol phosphodiesterase activity
2010-10-07 Added SECONDARY GO:0004434 (inositol or phosphatidylinositol phosphodiesterase activity)
2010-10-07 Added XREF EC:3.1.4.-
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
2008-04-01 Updated RELATION is a GO:0042578 (phosphoric ester hydrolase activity)
2007-08-09 Added SYNONYM endonuclease VIII activity
2007-08-09 Added SYNONYM phosphodiesterase
2007-08-09 Deleted SYNONYM endonuclease VIII activity
2007-08-09 Deleted SYNONYM phosphodiesterase
2006-02-09 Added XREF EC:3.1.4
2006-02-09 Deleted XREF EC:3.1.4.-
2005-08-10 Added SYNONYM endonuclease VIII activity
2004-04-19 Added SYNONYM phosphodiesterase
2004-04-16 Deleted SYNONYM phosphodiesterase
2003-03-26 Added DEFINITION Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
2003-03-19 Updated TERM phosphoric diester hydrolase activity
2002-06-07 Updated TERM phosphoric diester hydrolase
2002-06-07 Added SECONDARY GO:0016792 (phosphoric diester hydrolase)
2002-06-07 Added SYNONYM phosphodiesterase
2002-02-06 Updated TERM phosphodiesterase
2001-04-03 Updated TERM phosphodiesterase
2001-03-30 Added XREF EC:3.1.4.-
2001-03-30 Added TERM phosphodiesterase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM phosphoric diester hydrolase activity
2002-06-07 Updated TERM phosphoric diester hydrolase
2002-02-06 Updated TERM phosphodiesterase
2001-04-03 Updated TERM phosphodiesterase
2001-03-30 Added TERM phosphodiesterase

Definition/synonyms

Timestamp Action Category Detail
2010-10-07 Added SYNONYM inositol or phosphatidylinositol phosphodiesterase activity
2010-10-07 Added SYNONYM inositol/phosphatidylinositol phosphodiesterase activity
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
2007-08-09 Added SYNONYM endonuclease VIII activity
2007-08-09 Added SYNONYM phosphodiesterase
2007-08-09 Deleted SYNONYM endonuclease VIII activity
2007-08-09 Deleted SYNONYM phosphodiesterase
2005-08-10 Added SYNONYM endonuclease VIII activity
2004-04-19 Added SYNONYM phosphodiesterase
2004-04-16 Deleted SYNONYM phosphodiesterase
2003-03-26 Added DEFINITION Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
2002-06-07 Added SYNONYM phosphodiesterase

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0042578 (phosphoric ester hydrolase activity)

Cross-references

Timestamp Action Category Detail
2011-05-03 Deleted XREF EC:3.1.4.-
2010-10-07 Added XREF EC:3.1.4.-
2006-02-09 Added XREF EC:3.1.4
2006-02-09 Deleted XREF EC:3.1.4.-
2001-03-30 Added XREF EC:3.1.4.-

Other

Timestamp Action Category Detail
2010-10-07 Added SECONDARY GO:0004434 (inositol or phosphatidylinositol phosphodiesterase activity)
2002-06-07 Added SECONDARY GO:0016792 (phosphoric diester hydrolase)
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