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GO:0008024 positive transcription elongation factor complex b

Term Information

ID GO:0008024
Name positive transcription elongation factor complex b
Ontology Cellular Component
Definition A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains cyclin T and a cyclin-dependent protein kinase catalytic subunit.
PMID:10766736 PMID:16721054 PMID:17079683 PMID:19328067 PMID:7759473
Comment See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.
GONUTS GO:0008024 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact P-TEFb

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008024:
Relationship To GO:0008024 Child Term Child Term Name
Is a GO:0070691 dimeric positive transcription elongation factor complex b
Is a GO:0070692 trimeric positive transcription elongation factor complex b

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008024. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008024 based on the entire annotation set Co-occurrence statistics for GO:0008024 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-06-05 Added RELATION is a GO:0044428 (nuclear part)
2014-04-12 Deleted RELATION part of GO:0005634 (nucleus)
2014-02-09 Added RELATION part of GO:0005634 (nucleus)
2009-06-11 Deleted DEFINITION A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Consists of cyclin T and a cyclin-dependent protein kinase catalytic subunit.
2009-06-11 Added DEFINITION A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains cyclin T and a cyclin-dependent protein kinase catalytic subunit.
2009-06-11 Added RELATION is a GO:0032806 (carboxy-terminal domain protein kinase complex)
2009-02-28 Updated TERM positive transcription elongation factor complex b
2009-02-28 Deleted DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst, that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme.
2009-02-28 Added DEFINITION A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Consists of cyclin T and a cyclin-dependent protein kinase catalytic subunit.
2009-02-28 Added SYNONYM P-TEFb
2008-05-13 Added DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst, that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme.
2008-05-12 Deleted DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst, that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme.
2008-04-01 Updated RELATION is a GO:0008023 (transcription elongation factor complex)
2004-07-22 Updated DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst, that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme.
2003-07-23 Updated DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst (GO:0019907) that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme (GO:0016591).
2002-11-27 Added DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst (GO:0019907) that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme ; GO:0016591.
2002-02-06 Updated TERM transcription elongation factor complex b
2001-04-03 Updated TERM transcription elongation factor complex b
2001-03-30 Added TERM transcription elongation factor complex b

Term

Timestamp Action Category Detail
2009-02-28 Updated TERM positive transcription elongation factor complex b
2002-02-06 Updated TERM transcription elongation factor complex b
2001-04-03 Updated TERM transcription elongation factor complex b
2001-03-30 Added TERM transcription elongation factor complex b

Definition/synonyms

Timestamp Action Category Detail
2009-06-11 Deleted DEFINITION A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Consists of cyclin T and a cyclin-dependent protein kinase catalytic subunit.
2009-06-11 Added DEFINITION A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains cyclin T and a cyclin-dependent protein kinase catalytic subunit.
2009-02-28 Deleted DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst, that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme.
2009-02-28 Added DEFINITION A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Consists of cyclin T and a cyclin-dependent protein kinase catalytic subunit.
2009-02-28 Added SYNONYM P-TEFb
2008-05-13 Added DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst, that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme.
2008-05-12 Deleted DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst, that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme.
2004-07-22 Updated DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst, that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme.
2003-07-23 Updated DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst (GO:0019907) that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme (GO:0016591).
2002-11-27 Added DEFINITION A complex of cyclin T and a cyclin-dependent protein kinase, catalyst (GO:0019907) that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme ; GO:0016591.

Relationships

Timestamp Action Category Detail
2014-06-05 Added RELATION is a GO:0044428 (nuclear part)
2014-04-12 Deleted RELATION part of GO:0005634 (nucleus)
2014-02-09 Added RELATION part of GO:0005634 (nucleus)
2009-06-11 Added RELATION is a GO:0032806 (carboxy-terminal domain protein kinase complex)
2008-04-01 Updated RELATION is a GO:0008023 (transcription elongation factor complex)
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