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GO:0008021 synaptic vesicle

Term Information

ID GO:0008021
Name synaptic vesicle
Ontology Cellular Component
Definition A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
PMID:10099709
Comment This term should not be confused with GO:0097547 'synaptic vesicle protein transport vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles.
GONUTS GO:0008021 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow docked vesicle

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000362 GO:0044456 synapse part only_in_taxon 33208 Metazoa
GOTAX:0000365 GO:0045202 synapse only_in_taxon 33208 Metazoa
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR001285
InterPro IPR001359
InterPro IPR001565
InterPro IPR028715
NIF_Subcellular sao1071221672
UniProtKB-SubCell Synaptic vesicle
Wikipedia Synaptic_vesicle

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008021:
Relationship To GO:0008021 Child Term Child Term Name
Part of GO:0030672 synaptic vesicle membrane
Part of GO:0034592 synaptic vesicle lumen

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
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Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008021. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008021 based on the entire annotation set Co-occurrence statistics for GO:0008021 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-09-05 Added RELATION has part GO:1990476 (synaptic vesicle, resting pool)
2014-09-05 Added RELATION has part GO:1990475 (synaptic vesicle, recycling pool)
2014-09-05 Added RELATION has part GO:1990474 (synaptic vesicle, readily releasable pool)
2014-06-20 Added RELATION is a GO:0016023 (cytoplasmic membrane-bounded vesicle)
2014-06-20 Deleted RELATION is a GO:0030136 (clathrin-coated vesicle)
2014-01-08 Deleted DEFINITION A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2014-01-08 Added DEFINITION A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2013-02-02 Deleted RELATION part of GO:0045202 (synapse)
2012-12-13 Added SYNONYM docked vesicle
2012-10-29 Added RELATION part of GO:0045202 (synapse)
2010-02-04 Added XREF NIF_Subcellular:sao1071221672
2009-02-08 Added XREF Wikipedia:Synaptic_vesicle
2008-11-28 Deleted DEFINITION Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2008-11-28 Added DEFINITION A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2008-11-28 Added RELATION is a GO:0044456 (synapse part)
2008-05-13 Added DEFINITION Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2008-05-12 Deleted DEFINITION Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2008-04-01 Updated RELATION is a GO:0030136 (clathrin-coated vesicle)
2003-04-24 Updated DEFINITION Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2002-11-27 Updated DEFINITION Secretory organelles, some 50 nm in diameter, of pre-synaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the pre-synaptic plasma membrane.
2002-02-06 Updated TERM synaptic vesicle
2001-08-06 Added DEFINITION Secretory organelles, some 50nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the "active zone" of the presynaptic plasma membrane.
2001-04-03 Updated TERM synaptic vesicle
2001-03-30 Added TERM synaptic vesicle

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM synaptic vesicle
2001-04-03 Updated TERM synaptic vesicle
2001-03-30 Added TERM synaptic vesicle

Definition/synonyms

Timestamp Action Category Detail
2014-01-08 Deleted DEFINITION A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2014-01-08 Added DEFINITION A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2012-12-13 Added SYNONYM docked vesicle
2008-11-28 Deleted DEFINITION Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2008-11-28 Added DEFINITION A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2008-05-13 Added DEFINITION Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2008-05-12 Deleted DEFINITION Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2003-04-24 Updated DEFINITION Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2002-11-27 Updated DEFINITION Secretory organelles, some 50 nm in diameter, of pre-synaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the pre-synaptic plasma membrane.
2001-08-06 Added DEFINITION Secretory organelles, some 50nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the "active zone" of the presynaptic plasma membrane.

Relationships

Timestamp Action Category Detail
2014-09-05 Added RELATION has part GO:1990476 (synaptic vesicle, resting pool)
2014-09-05 Added RELATION has part GO:1990475 (synaptic vesicle, recycling pool)
2014-09-05 Added RELATION has part GO:1990474 (synaptic vesicle, readily releasable pool)
2014-06-20 Added RELATION is a GO:0016023 (cytoplasmic membrane-bounded vesicle)
2014-06-20 Deleted RELATION is a GO:0030136 (clathrin-coated vesicle)
2013-02-02 Deleted RELATION part of GO:0045202 (synapse)
2012-10-29 Added RELATION part of GO:0045202 (synapse)
2008-11-28 Added RELATION is a GO:0044456 (synapse part)
2008-04-01 Updated RELATION is a GO:0030136 (clathrin-coated vesicle)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao1071221672
2009-02-08 Added XREF Wikipedia:Synaptic_vesicle
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