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GO:0007269 neurotransmitter secretion

Term Information

ID GO:0007269
Name neurotransmitter secretion
Ontology Biological Process
Definition The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
GONUTS GO:0007269 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact neurotransmitter release

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR001359
InterPro IPR027158
InterPro IPR028712
InterPro IPR028713

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007269:
Relationship To GO:0007269 Child Term Child Term Name
Is a GO:0048791 calcium ion-dependent exocytosis of neurotransmitter
Is a GO:0048792 calcium ion-independent exocytosis of neurotransmitter
Positively regulates GO:0001956 positive regulation of neurotransmitter secretion
Part of GO:0010554 neurotransmitter secretory pathway
Is a GO:0014055 acetylcholine secretion, neurotransmission
Is a GO:0014860 neurotransmitter secretion involved in regulation of skeletal muscle contraction
Part of GO:0016079 synaptic vesicle exocytosis
Is a GO:0060096 serotonin secretion, neurotransmission
Regulates GO:0046928 regulation of neurotransmitter secretion
Negatively regulates GO:0046929 negative regulation of neurotransmitter secretion
Is a GO:0071911 synchronous neurotransmitter secretion
Is a GO:0071912 asynchronous neurotransmitter secretion
Is a GO:0061544 peptide secretion, neurotransmission
Is a GO:0061527 dopamine secretion, neurotransmission
Is a GO:0061529 epinephrine secretion, neurotransmission
Is a GO:0061530 aspartate secretion, neurotransmission
Is a GO:0061533 norepinephrine secretion, neurotransmission
Is a GO:0061534 gamma-aminobutyric acid secretion, neurotransmission
Is a GO:0061535 glutamate secretion, neurotransmission
Is a GO:0061537 glycine secretion, neurotransmission
Is a GO:0061538 histamine secretion, neurotransmission
Is a GO:0061540 octopamine secretion, neurotransmission

Protein Annotation

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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007269. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007269 based on the entire annotation set Co-occurrence statistics for GO:0007269 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-07-03 Deleted RELATION is a GO:0032940 (secretion by cell)
2010-04-30 Added RELATION is a GO:0023061 (signal release)
2010-04-30 Deleted RELATION is a GO:0003001 (generation of a signal involved in cell-cell signaling)
2008-07-27 Deleted DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, y aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2008-07-27 Added DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2008-05-13 Added RELATION is a GO:0006836 (neurotransmitter transport)
2008-05-13 Added DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, y aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2008-05-12 Deleted DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, y aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2008-04-01 Updated RELATION is a GO:0001505 (regulation of neurotransmitter levels)
2008-04-01 Updated RELATION is a GO:0003001 (generation of a signal involved in cell-cell signaling)
2008-04-01 Updated RELATION is a GO:0032940 (secretion by cell)
2007-11-27 Updated DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, y aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2007-08-09 Added SYNONYM neurotransmitter release
2007-08-09 Deleted SYNONYM neurotransmitter release
2004-04-19 Added SYNONYM neurotransmitter release
2004-04-16 Deleted SYNONYM neurotransmitter release
2002-11-27 Updated DEFINITION The regulated release of neurotransmitter into the synaptic cleft.
2002-08-15 Added SYNONYM neurotransmitter release
2002-08-15 Updated TERM neurotransmitter secretion
2002-02-06 Updated TERM neurotransmitter release
2001-08-06 Added DEFINITION The release of neurotransmitter into the synaptic cleft.
2001-04-03 Updated TERM neurotransmitter release
2001-03-30 Added TERM neurotransmitter release

Term

Timestamp Action Category Detail
2002-08-15 Updated TERM neurotransmitter secretion
2002-02-06 Updated TERM neurotransmitter release
2001-04-03 Updated TERM neurotransmitter release
2001-03-30 Added TERM neurotransmitter release

Definition/synonyms

Timestamp Action Category Detail
2008-07-27 Deleted DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, y aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2008-07-27 Added DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2008-05-13 Added DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, y aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2008-05-12 Deleted DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, y aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2007-11-27 Updated DEFINITION The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, y aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
2007-08-09 Added SYNONYM neurotransmitter release
2007-08-09 Deleted SYNONYM neurotransmitter release
2004-04-19 Added SYNONYM neurotransmitter release
2004-04-16 Deleted SYNONYM neurotransmitter release
2002-11-27 Updated DEFINITION The regulated release of neurotransmitter into the synaptic cleft.
2002-08-15 Added SYNONYM neurotransmitter release
2001-08-06 Added DEFINITION The release of neurotransmitter into the synaptic cleft.

Relationships

Timestamp Action Category Detail
2013-07-03 Deleted RELATION is a GO:0032940 (secretion by cell)
2010-04-30 Added RELATION is a GO:0023061 (signal release)
2010-04-30 Deleted RELATION is a GO:0003001 (generation of a signal involved in cell-cell signaling)
2008-05-13 Added RELATION is a GO:0006836 (neurotransmitter transport)
2008-04-01 Updated RELATION is a GO:0001505 (regulation of neurotransmitter levels)
2008-04-01 Updated RELATION is a GO:0003001 (generation of a signal involved in cell-cell signaling)
2008-04-01 Updated RELATION is a GO:0032940 (secretion by cell)
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