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GO:0007269 neurotransmitter secretion

The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.

Term Information

ID GO:0007269
Name neurotransmitter secretion
Ontology Biological Process
Definition The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
Comment

Synonyms

Type Synonym
exact neurotransmitter release

Cross-references associated with this term:

Database ID
INTERPRO IPR001359

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0065007 biological regulation
GO:0032501 multicellular organismal process
GO:0051179 localization
GO:0065008 regulation of biological quality
GO:0051234 establishment of localization
GO:0003008 system process
GO:0007154 cell communication
GO:0050877 neurological system process
GO:0006810 transport
GO:0007267 cell-cell signaling
GO:0051641 cellular localization
GO:0019226 transmission of nerve impulse
GO:0046903 secretion
GO:0003001 generation of a signal involved in cell-cell signaling
GO:0006836 neurotransmitter transport
GO:0051649 establishment of localization in cell
GO:0007268 synaptic transmission
GO:0032940 secretion by cell
GO:0001505 regulation of neurotransmitter levels
GO:0007269 neurotransmitter secretion

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0048790 maintenance of presynaptic active zone structure
I GO:0048791 calcium ion-dependent exocytosis of neurotransmitter
I GO:0048792 calcium ion-independent exocytosis of neurotransmitter
PR GO:0001956 positive regulation of neurotransmitter secretion
P GO:0010554 neurotransmitter secretory pathway
I GO:0014055 acetylcholine secretion
I GO:0014860 neurotransmitter secretion involved in regulation of skeletal muscle contraction
P GO:0016079 synaptic vesicle exocytosis
I GO:0060096 serotonin secretion, neurotransmission
R GO:0046928 regulation of neurotransmitter secretion
NR GO:0046929 negative regulation of neurotransmitter secretion

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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