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GO:0007256 activation of JNKK activity

Term Information

ID GO:0007256
Name activation of JNKK activity
Ontology Biological Process
Definition The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
PMID:11790549
GONUTS GO:0007256 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact activation of JUN kinase kinase activity
broad positive regulation of JUNKK activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000015 GO:0000165 MAPK cascade only_in_taxon 2759 Eukaryota
GOTAX:0000017 GO:0000186 activation of MAPKK activity only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR028560

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007256:
Relationship To GO:0007256 Child Term Child Term Name
Part of GO:0004706 JUN kinase kinase kinase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007256. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007256 based on the entire annotation set Co-occurrence statistics for GO:0007256 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-05-30 Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2013-05-30 Deleted DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2012-10-29 Added RELATION is a GO:0046328 (regulation of JNK cascade)
2012-01-22 Added RELATION positively regulates GO:0008545 (JUN kinase kinase activity)
2008-05-13 Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2008-05-12 Deleted DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2008-04-01 Updated RELATION is a GO:0000186 (activation of MAPKK activity)
2008-04-01 Updated RELATION part of GO:0007254 (JNK cascade)
2007-08-09 Added SYNONYM activation of JUN kinase kinase activity
2007-08-09 Added SYNONYM positive regulation of JUNKK activity
2007-08-09 Deleted SYNONYM activation of JUN kinase kinase activity
2007-08-09 Deleted SYNONYM positive regulation of JUNKK activity
2005-06-27 Added SYNONYM activation of JUN kinase kinase activity
2005-06-27 Deleted SYNONYM activation of JUN kinase kinase
2005-06-27 Updated TERM activation of JNKK activity
2005-06-24 Updated DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2005-01-08 Updated TERM activation of JNKK
2004-11-09 Updated DEFINITION Upregulation of JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2004-07-31 Added SYNONYM positive regulation of JUNKK activity
2004-04-19 Added SYNONYM activation of JUN kinase kinase
2004-04-16 Deleted SYNONYM activation of JUN kinase kinase
2003-04-24 Updated DEFINITION Catalysis of the phosphorylation and activation of JUN kinases (JNKs), members of a subfamily of mitogen activated protein (MAP) kinases.
2003-04-15 Updated DEFINITION Catalysis of the phosphorylation and activation of JUN kinases (JNKs), members of a sub-family of mitogen activated protein (MAP) kinases.
2003-04-12 Added SYNONYM activation of JUN kinase kinase
2003-04-12 Added DEFINITION Catalysis of the phosphorylation and activation of JUN kinases (JNKs), members of a sub-family of mitogen activated protein (MAP) kinases.
2003-04-12 Updated TERM activation of JUNKK
2002-02-06 Updated TERM activation of JUN kinase kinase
2001-04-03 Updated TERM activation of JUN kinase kinase
2001-03-30 Added TERM activation of JUN kinase kinase

Term

Timestamp Action Category Detail
2005-06-27 Updated TERM activation of JNKK activity
2005-01-08 Updated TERM activation of JNKK
2003-04-12 Updated TERM activation of JUNKK
2002-02-06 Updated TERM activation of JUN kinase kinase
2001-04-03 Updated TERM activation of JUN kinase kinase
2001-03-30 Added TERM activation of JUN kinase kinase

Definition/synonyms

Timestamp Action Category Detail
2013-05-30 Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2013-05-30 Deleted DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2008-05-13 Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2008-05-12 Deleted DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2007-08-09 Added SYNONYM activation of JUN kinase kinase activity
2007-08-09 Added SYNONYM positive regulation of JUNKK activity
2007-08-09 Deleted SYNONYM activation of JUN kinase kinase activity
2007-08-09 Deleted SYNONYM positive regulation of JUNKK activity
2005-06-27 Added SYNONYM activation of JUN kinase kinase activity
2005-06-27 Deleted SYNONYM activation of JUN kinase kinase
2005-06-24 Updated DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2004-11-09 Updated DEFINITION Upregulation of JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2004-07-31 Added SYNONYM positive regulation of JUNKK activity
2004-04-19 Added SYNONYM activation of JUN kinase kinase
2004-04-16 Deleted SYNONYM activation of JUN kinase kinase
2003-04-24 Updated DEFINITION Catalysis of the phosphorylation and activation of JUN kinases (JNKs), members of a subfamily of mitogen activated protein (MAP) kinases.
2003-04-15 Updated DEFINITION Catalysis of the phosphorylation and activation of JUN kinases (JNKs), members of a sub-family of mitogen activated protein (MAP) kinases.
2003-04-12 Added SYNONYM activation of JUN kinase kinase
2003-04-12 Added DEFINITION Catalysis of the phosphorylation and activation of JUN kinases (JNKs), members of a sub-family of mitogen activated protein (MAP) kinases.

Relationships

Timestamp Action Category Detail
2012-10-29 Added RELATION is a GO:0046328 (regulation of JNK cascade)
2012-01-22 Added RELATION positively regulates GO:0008545 (JUN kinase kinase activity)
2008-04-01 Updated RELATION is a GO:0000186 (activation of MAPKK activity)
2008-04-01 Updated RELATION part of GO:0007254 (JNK cascade)
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