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GO:0007254 JNK cascadeA cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
Term Information
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| Type | Synonym |
| broad | SAPK cascade |
| broad | stress-activated protein kinase cascade |
| narrow | MAPK10 cascade |
| narrow | JNK3 cascade |
| narrow | JNK2 cascade |
| narrow | JNK1 cascade |
| narrow | MAPK9 cascade |
| narrow | MAPK8 cascade |
GO:0016911 SAP kinase 4 activity |
(consider GO:0007254) |
GO:0016912 SAP kinase 5 activity |
(consider GO:0007254) |
GO:0016910 SAP kinase 3 activity |
(consider GO:0007254) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0008150 biological_process | |||||||||||||||
![]() | GO:0009987 cellular process | ||||||||||||||
![]() | ![]() | GO:0065007 biological regulation | |||||||||||||
![]() | ![]() | ![]() | GO:0050896 response to stimulus | ||||||||||||
![]() | ![]() | ![]() | ![]() | GO:0050789 regulation of biological process | |||||||||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0007154 cell communication | ||||||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0006950 response to stress | |||||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0051716 cellular response to stimulus | ||||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0050794 regulation of cellular process | |||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0033554 cellular response to stress | ||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0007165 signal transduction | |||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0007242 intracellular signaling cascade | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0007243 protein kinase cascade | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0000165 MAPKKK cascade | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0031098 stress-activated protein kinase signaling pathway | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0007254 JNK cascade |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| P | GO:0042655 activation of JNKKK activity |
| P | GO:0007256 activation of JNKK activity |
| P | GO:0007257 activation of JUN kinase activity |
| P | GO:0007258 JUN phosphorylation |
| R | GO:0046328 regulation of JNK cascade |
| NR | GO:0046329 negative regulation of JNK cascade |
| PR | GO:0046330 positive regulation of JNK cascade |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-21-04-03-45 |