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GO:0007224 smoothened signaling pathway

The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.

Term Information

ID GO:0007224
Name smoothened signaling pathway
Ontology Biological Process
Definition The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
Comment

Synonyms

Type Synonym
exact hedgehog signaling pathway
exact hh signaling pathway
exact hh signalling pathway
exact smoothened signalling pathway

Cross-references associated with this term:

Database ID
Wikipedia Hedgehog_signaling_pathway

Web service: term information

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GTerm?id=termID&format=format

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0007154 cell communication
GO:0050794 regulation of cellular process
GO:0007165 signal transduction
GO:0007166 cell surface receptor linked signal transduction
GO:0007224 smoothened signaling pathway

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
R GO:0008589 regulation of smoothened signaling pathway
P GO:0007225 patched ligand processing
P GO:0007227 signal transduction downstream of smoothened
P GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway
I GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning
NR GO:0045879 negative regulation of smoothened signaling pathway
PR GO:0045880 positive regulation of smoothened signaling pathway
I GO:0060506 smoothened signaling pathway involved in lung development
I GO:0003271 regulation of second heart field cardioblast proliferation by smoothened receptor signaling pathway
I GO:0060783 mesenchymal smoothened signaling pathway involved in prostate gland development
I GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning
I GO:0021938 smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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