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GO:0007216 G-protein coupled glutamate receptor signaling pathway

Term Information

ID GO:0007216
Name G-protein coupled glutamate receptor signaling pathway
Ontology Biological Process
Definition A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
PMID:9131252
GONUTS GO:0007216 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact metabotropic glutamate receptor signaling pathway
exact metabotropic glutamate receptor signalling pathway

GO Discussions

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Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR029588

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007216:
Relationship To GO:0007216 Child Term Child Term Name
Is a GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
Is a GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007216. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007216 based on the entire annotation set Co-occurrence statistics for GO:0007216 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-01-18 Deleted DEFINITION The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor coupled to effectors through GTP-binding proteins.
2012-01-18 Added DEFINITION A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
2011-12-21 Added SYNONYM metabotropic glutamate receptor signaling pathway
2011-12-21 Updated TERM G-protein coupled glutamate receptor signaling pathway
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor coupled to effectors through GTP-binding proteins.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor coupled to effectors through GTP-binding proteins.
2008-04-01 Updated RELATION is a GO:0007215 (glutamate receptor signaling pathway)
2008-04-01 Updated RELATION is a GO:0007186 (G-protein coupled receptor signaling pathway)
2007-08-09 Added SYNONYM metabotropic glutamate receptor signalling pathway
2007-08-09 Deleted SYNONYM metabotropic glutamate receptor signalling pathway
2004-07-15 Added DEFINITION The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor coupled to effectors through GTP-binding proteins.
2004-04-19 Added SYNONYM metabotropic glutamate receptor signalling pathway
2004-04-16 Deleted SYNONYM metabotropic glutamate receptor signalling pathway
2003-11-13 Added SYNONYM metabotropic glutamate receptor signalling pathway
2002-02-06 Updated TERM metabotropic glutamate receptor signaling pathway
2001-04-03 Updated TERM metabotropic glutamate receptor signaling pathway
2001-03-30 Added TERM metabotropic glutamate receptor signaling pathway

Term

Timestamp Action Category Detail
2011-12-21 Updated TERM G-protein coupled glutamate receptor signaling pathway
2002-02-06 Updated TERM metabotropic glutamate receptor signaling pathway
2001-04-03 Updated TERM metabotropic glutamate receptor signaling pathway
2001-03-30 Added TERM metabotropic glutamate receptor signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2012-01-18 Deleted DEFINITION The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor coupled to effectors through GTP-binding proteins.
2012-01-18 Added DEFINITION A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
2011-12-21 Added SYNONYM metabotropic glutamate receptor signaling pathway
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor coupled to effectors through GTP-binding proteins.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor coupled to effectors through GTP-binding proteins.
2007-08-09 Added SYNONYM metabotropic glutamate receptor signalling pathway
2007-08-09 Deleted SYNONYM metabotropic glutamate receptor signalling pathway
2004-07-15 Added DEFINITION The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor coupled to effectors through GTP-binding proteins.
2004-04-19 Added SYNONYM metabotropic glutamate receptor signalling pathway
2004-04-16 Deleted SYNONYM metabotropic glutamate receptor signalling pathway
2003-11-13 Added SYNONYM metabotropic glutamate receptor signalling pathway

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0007215 (glutamate receptor signaling pathway)
2008-04-01 Updated RELATION is a GO:0007186 (G-protein coupled receptor signaling pathway)
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