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GO:0007213 G-protein coupled acetylcholine receptor signaling pathway

Term Information

ID GO:0007213
Name G-protein coupled acetylcholine receptor signaling pathway
Ontology Biological Process
Definition Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.
GONUTS GO:0007213 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact muscarinic acetylcholine receptor signaling pathway
exact acetylcholine receptor signalling, muscarinic pathway

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Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR004850

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007213:
Relationship To GO:0007213 Child Term Child Term Name
Is a GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
Is a GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
Part of GO:0016907 G-protein coupled acetylcholine receptor activity
Is a GO:0086093 G-protein coupled acetylcholine receptor signaling pathway involved in involved in heart process

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007213. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007213 based on the entire annotation set Co-occurrence statistics for GO:0007213 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-10-24 Added DEFINITION Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.
2011-10-24 Added SYNONYM muscarinic acetylcholine receptor signaling pathway
2011-10-24 Updated TERM G-protein coupled acetylcholine receptor signaling pathway
2011-10-24 Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2009-01-31 Updated TERM muscarinic acetylcholine receptor signaling pathway
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2008-04-01 Updated RELATION is a GO:0007186 (G-protein coupled receptor signaling pathway)
2007-08-09 Added SYNONYM acetylcholine receptor signalling, muscarinic pathway
2007-08-09 Deleted SYNONYM acetylcholine receptor signalling, muscarinic pathway
2004-07-22 Updated TERM acetylcholine receptor signaling, muscarinic pathway
2004-07-22 Deleted SYNONYM acetyl choline receptor signalling, muscarinic pathway
2004-07-22 Added SYNONYM acetylcholine receptor signalling, muscarinic pathway
2004-07-15 Added DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2004-04-19 Added SYNONYM acetyl choline receptor signalling, muscarinic pathway
2004-04-16 Deleted SYNONYM acetyl choline receptor signalling, muscarinic pathway
2003-11-13 Added SYNONYM acetyl choline receptor signalling, muscarinic pathway
2002-02-06 Updated TERM acetyl choline receptor signaling, muscarinic pathway
2001-04-03 Updated TERM acetyl choline receptor signaling, muscarinic pathway
2001-03-30 Added TERM acetyl choline receptor signaling, muscarinic pathway

Term

Timestamp Action Category Detail
2011-10-24 Updated TERM G-protein coupled acetylcholine receptor signaling pathway
2009-01-31 Updated TERM muscarinic acetylcholine receptor signaling pathway
2004-07-22 Updated TERM acetylcholine receptor signaling, muscarinic pathway
2002-02-06 Updated TERM acetyl choline receptor signaling, muscarinic pathway
2001-04-03 Updated TERM acetyl choline receptor signaling, muscarinic pathway
2001-03-30 Added TERM acetyl choline receptor signaling, muscarinic pathway

Definition/synonyms

Timestamp Action Category Detail
2011-10-24 Added DEFINITION Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.
2011-10-24 Added SYNONYM muscarinic acetylcholine receptor signaling pathway
2011-10-24 Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2007-08-09 Added SYNONYM acetylcholine receptor signalling, muscarinic pathway
2007-08-09 Deleted SYNONYM acetylcholine receptor signalling, muscarinic pathway
2004-07-22 Deleted SYNONYM acetyl choline receptor signalling, muscarinic pathway
2004-07-22 Added SYNONYM acetylcholine receptor signalling, muscarinic pathway
2004-07-15 Added DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2004-04-19 Added SYNONYM acetyl choline receptor signalling, muscarinic pathway
2004-04-16 Deleted SYNONYM acetyl choline receptor signalling, muscarinic pathway
2003-11-13 Added SYNONYM acetyl choline receptor signalling, muscarinic pathway

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0007186 (G-protein coupled receptor signaling pathway)
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