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GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.

Term Information

ID GO:0007200
Name activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
Ontology Biological Process
Definition The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
Comment

Synonyms

Type Synonym
exact G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
related phospholipase C-activating dopamine receptor signaling pathway
exact G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
exact G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
exact G protein signaling, coupled to IP3 second messenger (phospholipase C activating)

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0065009 regulation of molecular function
GO:0007154 cell communication
GO:0050790 regulation of catalytic activity
GO:0044093 positive regulation of molecular function
GO:0050794 regulation of cellular process
GO:0051336 regulation of hydrolase activity
GO:0060191 regulation of lipase activity
GO:0043085 positive regulation of catalytic activity
GO:0010517 regulation of phospholipase activity
GO:0007165 signal transduction
GO:0007242 intracellular signaling cascade
GO:0007166 cell surface receptor linked signal transduction
GO:0051345 positive regulation of hydrolase activity
GO:0007186 G-protein coupled receptor protein signaling pathway
GO:0019932 second-messenger-mediated signaling
GO:0060193 positive regulation of lipase activity
GO:0048015 phosphoinositide-mediated signaling
GO:0010518 positive regulation of phospholipase activity
GO:0010863 positive regulation of phospholipase C activity
GO:0007202 activation of phospholipase C activity
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0007206 activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway
I GO:0007207 activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway
I GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway
I GO:0007209 activation of phospholipase C activity by tachykinin receptor signaling pathway
I GO:0030265 rhodopsin mediated G-protein signaling, coupled to IP3 second messenger
P GO:0051482 elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
I GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway
NR GO:0030845 inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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