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GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway

Term Information

ID GO:0007200
Name phospholipase C-activating G-protein coupled receptor signaling pathway
Ontology Biological Process
Definition The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
Comment This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) activity.
GONUTS GO:0007200 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
exact G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
related activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
exact G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
exact G-protein coupled receptor signaling pathway coupled to IP3 second messenger
exact G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
narrow phospholipase C-activating dopamine receptor signaling pathway
exact PLC-activating GPCR signaling pathway

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR000142
InterPro IPR000356
InterPro IPR000371

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007200:
Relationship To GO:0007200 Child Term Child Term Name
Is a GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway
Is a GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
Is a GO:0007208 phospholipase C-activating serotonin receptor signaling pathway
Is a GO:0007209 phospholipase C-activating tachykinin receptor signaling pathway
Is a GO:0030265 phospholipase C-activating rhodopsin mediated signaling pathway
Part of GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
Is a GO:0071882 phospholipase C-activating adrenergic receptor signaling pathway
Is a GO:0060158 phospholipase C-activating dopamine receptor signaling pathway
Has part GO:0007202 activation of phospholipase C activity
Has part GO:0048016 inositol phosphate-mediated signaling
Regulates GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
Negatively regulates GO:1900737 negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
Positively regulates GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
Is a GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007200. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007200 based on the entire annotation set Co-occurrence statistics for GO:0007200 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-05-27 Deleted RELATION is a GO:0048016 (inositol phosphate-mediated signaling)
2012-05-27 Deleted RELATION is a GO:0007202 (activation of phospholipase C activity)
2012-05-27 Added SYNONYM activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
2012-05-27 Added SYNONYM G-protein coupled receptor signaling pathway coupled to IP3 second messenger
2012-05-27 Added SYNONYM phospholipase C-activating dopamine receptor signaling pathway
2012-05-27 Added SYNONYM PLC-activating GPCR signaling pathway
2012-05-27 Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2012-05-27 Deleted SYNONYM phospholipase C-activating dopamine receptor signaling pathway
2012-05-27 Updated TERM phospholipase C-activating G-protein coupled receptor signaling pathway
2012-05-27 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
2010-12-15 Added RELATION is a GO:0048016 (inositol phosphate-mediated signaling)
2010-12-15 Deleted RELATION is a GO:0048015 (phosphatidylinositol-mediated signaling)
2009-01-31 Updated TERM activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
2009-01-31 Added SYNONYM G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2009-01-31 Added SYNONYM phospholipase C-activating dopamine receptor signaling pathway
2009-01-31 Added RELATION is a GO:0007202 (activation of phospholipase C activity)
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2008-04-01 Updated RELATION is a GO:0007186 (G-protein coupled receptor signaling pathway)
2008-04-01 Updated RELATION is a GO:0048015 (phosphatidylinositol-mediated signaling)
2007-08-09 Added SYNONYM G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Added SYNONYM G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Added SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Deleted SYNONYM G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Deleted SYNONYM G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Deleted SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2005-06-27 Added SYNONYM G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2005-06-27 Added SYNONYM G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2004-07-24 Updated DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2004-07-15 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inostol trisphosphate.
2004-04-19 Added SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2004-04-16 Deleted SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2003-11-13 Added SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2002-02-06 Updated TERM G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2001-04-03 Updated TERM G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2001-03-30 Added TERM G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)

Term

Timestamp Action Category Detail
2012-05-27 Updated TERM phospholipase C-activating G-protein coupled receptor signaling pathway
2009-01-31 Updated TERM activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
2002-02-06 Updated TERM G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2001-04-03 Updated TERM G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2001-03-30 Added TERM G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)

Definition/synonyms

Timestamp Action Category Detail
2012-05-27 Added SYNONYM activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
2012-05-27 Added SYNONYM G-protein coupled receptor signaling pathway coupled to IP3 second messenger
2012-05-27 Added SYNONYM phospholipase C-activating dopamine receptor signaling pathway
2012-05-27 Added SYNONYM PLC-activating GPCR signaling pathway
2012-05-27 Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2012-05-27 Deleted SYNONYM phospholipase C-activating dopamine receptor signaling pathway
2012-05-27 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
2009-01-31 Added SYNONYM G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2009-01-31 Added SYNONYM phospholipase C-activating dopamine receptor signaling pathway
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2007-08-09 Added SYNONYM G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Added SYNONYM G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Added SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Deleted SYNONYM G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Deleted SYNONYM G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2007-08-09 Deleted SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2005-06-27 Added SYNONYM G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
2005-06-27 Added SYNONYM G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2004-07-24 Updated DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2004-07-15 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inostol trisphosphate.
2004-04-19 Added SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2004-04-16 Deleted SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
2003-11-13 Added SYNONYM G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)

Relationships

Timestamp Action Category Detail
2012-05-27 Deleted RELATION is a GO:0048016 (inositol phosphate-mediated signaling)
2012-05-27 Deleted RELATION is a GO:0007202 (activation of phospholipase C activity)
2010-12-15 Added RELATION is a GO:0048016 (inositol phosphate-mediated signaling)
2010-12-15 Deleted RELATION is a GO:0048015 (phosphatidylinositol-mediated signaling)
2009-01-31 Added RELATION is a GO:0007202 (activation of phospholipase C activity)
2008-04-01 Updated RELATION is a GO:0007186 (G-protein coupled receptor signaling pathway)
2008-04-01 Updated RELATION is a GO:0048015 (phosphatidylinositol-mediated signaling)
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