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GO:0007194 negative regulation of adenylate cyclase activity

Term Information

ID GO:0007194
Name negative regulation of adenylate cyclase activity
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.
GONUTS GO:0007194 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact down regulation of adenylate cyclase activity
exact negative regulation of adenylyl cyclase activity
exact down-regulation of adenylate cyclase activity
exact downregulation of adenylate cyclase activity
narrow inhibition of adenylate cyclase activity
related adenylate cyclase inhibitor

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR003906
InterPro IPR003907
InterPro IPR003908
InterPro IPR008109

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007194:
Relationship To GO:0007194 Child Term Child Term Name
Is a GO:0075077 negative regulation by host of symbiont adenylate cyclase activity
Is a GO:0075108 negative regulation by symbiont of host adenylate cyclase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007194. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007194 based on the entire annotation set Co-occurrence statistics for GO:0007194 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-05-27 Added RELATION has part GO:0007193 (adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway)
2011-11-24 Added RELATION is a GO:0030818 (negative regulation of cAMP biosynthetic process)
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2010-06-15 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2010-06-09 Updated TERM negative regulation of adenylate cyclase activity
2010-06-08 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2010-06-08 Updated TERM negative regulation of adenylate cyclase activity
2009-02-25 Updated TERM negative regulation of adenylate cyclase activity
2009-02-25 Deleted RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2009-02-22 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2009-02-22 Updated TERM negative regulation of adenylate cyclase activity
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2008-04-01 Updated RELATION is a GO:0031280 (negative regulation of cyclase activity)
2008-04-01 Updated RELATION is a GO:0045761 (regulation of adenylate cyclase activity)
2008-04-01 Updated RELATION is a GO:0051350 (negative regulation of lyase activity)
2007-08-09 Added SYNONYM adenylate cyclase inhibitor
2007-08-09 Added SYNONYM down regulation of adenylate cyclase activity
2007-08-09 Added SYNONYM down-regulation of adenylate cyclase activity
2007-08-09 Added SYNONYM downregulation of adenylate cyclase activity
2007-08-09 Added SYNONYM inhibition of adenylate cyclase activity
2007-08-09 Added SYNONYM negative regulation of adenylyl cyclase activity
2007-08-09 Deleted SYNONYM down regulation of adenylate cyclase activity
2007-08-09 Deleted SYNONYM down-regulation of adenylate cyclase activity
2007-08-09 Deleted SYNONYM downregulation of adenylate cyclase activity
2007-08-09 Deleted SYNONYM inhibition of adenylate cyclase activity
2007-08-09 Deleted SYNONYM adenylate cyclase inhibitor
2007-08-09 Deleted SYNONYM negative regulation of adenylyl cyclase activity
2007-02-23 Added SYNONYM down regulation of adenylate cyclase activity
2007-02-23 Added SYNONYM down-regulation of adenylate cyclase activity
2007-02-23 Added SYNONYM downregulation of adenylate cyclase activity
2007-02-23 Added SYNONYM inhibition of adenylate cyclase activity
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of adenylate cyclase activity.
2005-08-15 Added SYNONYM adenylate cyclase inhibitor
2004-09-03 Added SYNONYM negative regulation of adenylyl cyclase activity
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of adenylate cyclase activity.
2002-08-20 Updated TERM negative regulation of adenylate cyclase activity
2002-07-15 Updated TERM negative regulation of adenylate cyclase
2002-02-06 Updated TERM adenylate cyclase inhibition
2001-04-03 Updated TERM adenylate cyclase inhibition
2001-03-30 Added TERM adenylate cyclase inhibition

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM negative regulation of adenylate cyclase activity
2010-06-08 Updated TERM negative regulation of adenylate cyclase activity
2009-02-25 Updated TERM negative regulation of adenylate cyclase activity
2009-02-22 Updated TERM negative regulation of adenylate cyclase activity
2002-08-20 Updated TERM negative regulation of adenylate cyclase activity
2002-07-15 Updated TERM negative regulation of adenylate cyclase
2002-02-06 Updated TERM adenylate cyclase inhibition
2001-04-03 Updated TERM adenylate cyclase inhibition
2001-03-30 Added TERM adenylate cyclase inhibition

Definition/synonyms

Timestamp Action Category Detail
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2007-08-09 Added SYNONYM adenylate cyclase inhibitor
2007-08-09 Added SYNONYM down regulation of adenylate cyclase activity
2007-08-09 Added SYNONYM down-regulation of adenylate cyclase activity
2007-08-09 Added SYNONYM downregulation of adenylate cyclase activity
2007-08-09 Added SYNONYM inhibition of adenylate cyclase activity
2007-08-09 Added SYNONYM negative regulation of adenylyl cyclase activity
2007-08-09 Deleted SYNONYM down regulation of adenylate cyclase activity
2007-08-09 Deleted SYNONYM down-regulation of adenylate cyclase activity
2007-08-09 Deleted SYNONYM downregulation of adenylate cyclase activity
2007-08-09 Deleted SYNONYM inhibition of adenylate cyclase activity
2007-08-09 Deleted SYNONYM adenylate cyclase inhibitor
2007-08-09 Deleted SYNONYM negative regulation of adenylyl cyclase activity
2007-02-23 Added SYNONYM down regulation of adenylate cyclase activity
2007-02-23 Added SYNONYM down-regulation of adenylate cyclase activity
2007-02-23 Added SYNONYM downregulation of adenylate cyclase activity
2007-02-23 Added SYNONYM inhibition of adenylate cyclase activity
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of adenylate cyclase activity.
2005-08-15 Added SYNONYM adenylate cyclase inhibitor
2004-09-03 Added SYNONYM negative regulation of adenylyl cyclase activity
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of adenylate cyclase activity.

Relationships

Timestamp Action Category Detail
2012-05-27 Added RELATION has part GO:0007193 (adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway)
2011-11-24 Added RELATION is a GO:0030818 (negative regulation of cAMP biosynthetic process)
2010-06-15 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2010-06-08 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2009-02-25 Deleted RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2009-02-22 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2008-04-01 Updated RELATION is a GO:0031280 (negative regulation of cyclase activity)
2008-04-01 Updated RELATION is a GO:0045761 (regulation of adenylate cyclase activity)
2008-04-01 Updated RELATION is a GO:0051350 (negative regulation of lyase activity)
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