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GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway

Term Information

ID GO:0007193
Name adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
Ontology Biological Process
Definition The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).
Comment This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase inhibition.
GONUTS GO:0007193 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related inhibition of adenylate cyclase activity by G-protein signaling pathway
exact G protein signaling, adenylyl cyclase inhibiting pathway
exact GPCR signaling pathway via inhibition of adenylate cyclase activity
exact adenylate cyclase-inhibiting GPCR signaling pathway
exact G protein signaling, adenylate cyclase inhibiting pathway
exact G-protein signalling, adenylyl cyclase inhibiting pathway
exact G-protein signaling, adenylate cyclase inhibiting pathway
exact G-protein signalling, adenylate cyclase inhibiting pathway
exact G-protein signaling, adenylyl cyclase inhibiting pathway
exact G protein signalling, adenylyl cyclase inhibiting pathway
exact G protein signalling, adenylate cyclase inhibiting pathway

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007193:
Relationship To GO:0007193 Child Term Child Term Name
Is a GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway
Is a GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway
Is a GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway
Is a GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
Is a GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
Is a GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007193. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007193 based on the entire annotation set Co-occurrence statistics for GO:0007193 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-05-27 Deleted RELATION is a GO:0007194 (negative regulation of adenylate cyclase activity)
2012-05-27 Added SYNONYM GPCR signaling pathway via inhibition of adenylate cyclase activity
2012-05-27 Added SYNONYM adenylate cyclase-inhibiting GPCR signaling pathway
2012-05-27 Added SYNONYM inhibition of adenylate cyclase activity by G-protein signaling pathway
2012-05-27 Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2012-05-27 Updated TERM adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
2012-05-27 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).
2010-06-09 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling pathway
2010-06-08 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling pathway
2009-11-11 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling pathway
2009-02-25 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling
2009-02-22 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling
2009-01-31 Added SYNONYM G-protein signaling, adenylate cyclase inhibiting pathway
2009-01-31 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling
2008-10-02 Added RELATION is a GO:0007194 (negative regulation of adenylate cyclase activity)
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2008-04-01 Updated RELATION is a GO:0007188 (adenylate cyclase-modulating G-protein coupled receptor signaling pathway)
2007-08-09 Added SYNONYM G protein signaling, adenylate cyclase inhibiting pathway
2007-08-09 Added SYNONYM G protein signaling, adenylyl cyclase inhibiting pathway
2007-08-09 Added SYNONYM G protein signalling, adenylate cyclase inhibiting pathway
2007-08-09 Added SYNONYM G protein signalling, adenylyl cyclase inhibiting pathway
2007-08-09 Added SYNONYM G-protein signaling, adenylyl cyclase inhibiting pathway
2007-08-09 Added SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway
2007-08-09 Added SYNONYM G-protein signalling, adenylyl cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G protein signaling, adenylate cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G protein signaling, adenylyl cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G protein signalling, adenylate cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G protein signalling, adenylyl cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G-protein signaling, adenylyl cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G-protein signalling, adenylyl cyclase inhibiting pathway
2005-06-27 Added SYNONYM G protein signaling, adenylate cyclase inhibiting pathway
2005-06-27 Added SYNONYM G protein signaling, adenylyl cyclase inhibiting pathway
2005-06-27 Added SYNONYM G protein signalling, adenylate cyclase inhibiting pathway
2005-06-27 Added SYNONYM G protein signalling, adenylyl cyclase inhibiting pathway
2005-06-27 Added SYNONYM G-protein signalling, adenylyl cyclase inhibiting pathway
2004-09-03 Added SYNONYM G-protein signaling, adenylyl cyclase inhibiting pathway
2004-07-28 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2004-04-19 Added SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway
2004-04-16 Deleted SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway
2003-11-13 Added SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway
2002-02-06 Updated TERM G-protein signaling, adenylate cyclase inhibiting pathway
2001-04-03 Updated TERM G-protein signaling, adenylate cyclase inhibiting pathway
2001-03-30 Added TERM G-protein signaling, adenylate cyclase inhibiting pathway

Term

Timestamp Action Category Detail
2012-05-27 Updated TERM adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
2010-06-09 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling pathway
2010-06-08 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling pathway
2009-11-11 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling pathway
2009-02-25 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling
2009-02-22 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling
2009-01-31 Updated TERM inhibition of adenylate cyclase activity by G-protein signaling
2002-02-06 Updated TERM G-protein signaling, adenylate cyclase inhibiting pathway
2001-04-03 Updated TERM G-protein signaling, adenylate cyclase inhibiting pathway
2001-03-30 Added TERM G-protein signaling, adenylate cyclase inhibiting pathway

Definition/synonyms

Timestamp Action Category Detail
2012-05-27 Added SYNONYM GPCR signaling pathway via inhibition of adenylate cyclase activity
2012-05-27 Added SYNONYM adenylate cyclase-inhibiting GPCR signaling pathway
2012-05-27 Added SYNONYM inhibition of adenylate cyclase activity by G-protein signaling pathway
2012-05-27 Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2012-05-27 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).
2009-01-31 Added SYNONYM G-protein signaling, adenylate cyclase inhibiting pathway
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2007-08-09 Added SYNONYM G protein signaling, adenylate cyclase inhibiting pathway
2007-08-09 Added SYNONYM G protein signaling, adenylyl cyclase inhibiting pathway
2007-08-09 Added SYNONYM G protein signalling, adenylate cyclase inhibiting pathway
2007-08-09 Added SYNONYM G protein signalling, adenylyl cyclase inhibiting pathway
2007-08-09 Added SYNONYM G-protein signaling, adenylyl cyclase inhibiting pathway
2007-08-09 Added SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway
2007-08-09 Added SYNONYM G-protein signalling, adenylyl cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G protein signaling, adenylate cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G protein signaling, adenylyl cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G protein signalling, adenylate cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G protein signalling, adenylyl cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G-protein signaling, adenylyl cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway
2007-08-09 Deleted SYNONYM G-protein signalling, adenylyl cyclase inhibiting pathway
2005-06-27 Added SYNONYM G protein signaling, adenylate cyclase inhibiting pathway
2005-06-27 Added SYNONYM G protein signaling, adenylyl cyclase inhibiting pathway
2005-06-27 Added SYNONYM G protein signalling, adenylate cyclase inhibiting pathway
2005-06-27 Added SYNONYM G protein signalling, adenylyl cyclase inhibiting pathway
2005-06-27 Added SYNONYM G-protein signalling, adenylyl cyclase inhibiting pathway
2004-09-03 Added SYNONYM G-protein signaling, adenylyl cyclase inhibiting pathway
2004-07-28 Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2004-04-19 Added SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway
2004-04-16 Deleted SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway
2003-11-13 Added SYNONYM G-protein signalling, adenylate cyclase inhibiting pathway

Relationships

Timestamp Action Category Detail
2012-05-27 Deleted RELATION is a GO:0007194 (negative regulation of adenylate cyclase activity)
2008-10-02 Added RELATION is a GO:0007194 (negative regulation of adenylate cyclase activity)
2008-04-01 Updated RELATION is a GO:0007188 (adenylate cyclase-modulating G-protein coupled receptor signaling pathway)
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