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GO:0007179 transforming growth factor beta receptor signaling pathway

Term Information

ID GO:0007179
Name transforming growth factor beta receptor signaling pathway
Ontology Biological Process
Definition A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
GONUTS GO:0007179 Wiki Page
Acknowledgements This term was created by the GO Consortium with support from BHF logo

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact transforming growth factor beta receptor signalling pathway
exact TGFbeta receptor signaling pathway
exact TGF-beta receptor signalling pathway
exact TGF-beta receptor signaling pathway
exact TGFbeta receptor signalling pathway

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0001010 GO:0070848 response to growth factor never_in_taxon 2, 2157, 4751 Fungi or Bacteria or Archaea
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR013019
InterPro IPR017194

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007179:
Relationship To GO:0007179 Child Term Child Term Name
Part of GO:0007181 transforming growth factor beta receptor complex assembly
Regulates GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
Positively regulates GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
Negatively regulates GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
Is a GO:0060826 transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation
Is a GO:0060835 transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification
Is a GO:0060797 transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment
Is a GO:0090010 transforming growth factor beta receptor signaling pathway involved in primitive streak formation
Is a GO:0035463 transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry
Is a GO:1901048 transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007179. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007179 based on the entire annotation set Co-occurrence statistics for GO:0007179 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-11-23 Added RELATION is a GO:0071560 (cellular response to transforming growth factor beta stimulus)
2012-01-18 Added DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2012-01-18 Deleted DEFINITION The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.
2008-04-01 Updated RELATION is a GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway)
2007-08-09 Added SYNONYM TGF-beta receptor signaling pathway
2007-08-09 Added SYNONYM TGF-beta receptor signalling pathway
2007-08-09 Added SYNONYM TGFbeta receptor signaling pathway
2007-08-09 Added SYNONYM TGFbeta receptor signalling pathway
2007-08-09 Added SYNONYM transforming growth factor beta receptor signalling pathway
2007-08-09 Deleted SYNONYM TGF-beta receptor signaling pathway
2007-08-09 Deleted SYNONYM TGF-beta receptor signalling pathway
2007-08-09 Deleted SYNONYM TGFbeta receptor signaling pathway
2007-08-09 Deleted SYNONYM TGFbeta receptor signalling pathway
2007-08-09 Deleted SYNONYM transforming growth factor beta receptor signalling pathway
2004-10-08 Added SYNONYM TGF-beta receptor signalling pathway
2004-10-08 Added SYNONYM TGFbeta receptor signalling pathway
2004-06-24 Added DEFINITION The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.
2004-04-19 Added SYNONYM TGF-beta receptor signaling pathway
2004-04-19 Added SYNONYM TGFbeta receptor signaling pathway
2004-04-19 Added SYNONYM transforming growth factor beta receptor signalling pathway
2004-04-16 Deleted SYNONYM TGF-beta receptor signaling pathway
2004-04-16 Deleted SYNONYM TGFbeta receptor signaling pathway
2004-04-16 Deleted SYNONYM transforming growth factor beta receptor signalling pathway
2004-01-22 Updated TERM transforming growth factor beta receptor signaling pathway
2004-01-22 Added SYNONYM TGF-beta receptor signaling pathway
2004-01-22 Added SYNONYM TGFbeta receptor signaling pathway
2004-01-22 Added SYNONYM transforming growth factor beta receptor signalling pathway
2004-01-22 Deleted SYNONYM TGFbeta receptor signalling pathway
2003-11-13 Added SYNONYM TGFbeta receptor signalling pathway
2002-02-06 Updated TERM TGFbeta receptor signaling pathway
2001-04-03 Updated TERM TGFbeta receptor signaling pathway
2001-03-30 Added TERM TGFbeta receptor signaling pathway

Term

Timestamp Action Category Detail
2004-01-22 Updated TERM transforming growth factor beta receptor signaling pathway
2002-02-06 Updated TERM TGFbeta receptor signaling pathway
2001-04-03 Updated TERM TGFbeta receptor signaling pathway
2001-03-30 Added TERM TGFbeta receptor signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2012-01-18 Added DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2012-01-18 Deleted DEFINITION The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.
2007-08-09 Added SYNONYM TGF-beta receptor signaling pathway
2007-08-09 Added SYNONYM TGF-beta receptor signalling pathway
2007-08-09 Added SYNONYM TGFbeta receptor signaling pathway
2007-08-09 Added SYNONYM TGFbeta receptor signalling pathway
2007-08-09 Added SYNONYM transforming growth factor beta receptor signalling pathway
2007-08-09 Deleted SYNONYM TGF-beta receptor signaling pathway
2007-08-09 Deleted SYNONYM TGF-beta receptor signalling pathway
2007-08-09 Deleted SYNONYM TGFbeta receptor signaling pathway
2007-08-09 Deleted SYNONYM TGFbeta receptor signalling pathway
2007-08-09 Deleted SYNONYM transforming growth factor beta receptor signalling pathway
2004-10-08 Added SYNONYM TGF-beta receptor signalling pathway
2004-10-08 Added SYNONYM TGFbeta receptor signalling pathway
2004-06-24 Added DEFINITION The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.
2004-04-19 Added SYNONYM TGF-beta receptor signaling pathway
2004-04-19 Added SYNONYM TGFbeta receptor signaling pathway
2004-04-19 Added SYNONYM transforming growth factor beta receptor signalling pathway
2004-04-16 Deleted SYNONYM TGF-beta receptor signaling pathway
2004-04-16 Deleted SYNONYM TGFbeta receptor signaling pathway
2004-04-16 Deleted SYNONYM transforming growth factor beta receptor signalling pathway
2004-01-22 Added SYNONYM TGF-beta receptor signaling pathway
2004-01-22 Added SYNONYM TGFbeta receptor signaling pathway
2004-01-22 Added SYNONYM transforming growth factor beta receptor signalling pathway
2004-01-22 Deleted SYNONYM TGFbeta receptor signalling pathway
2003-11-13 Added SYNONYM TGFbeta receptor signalling pathway

Relationships

Timestamp Action Category Detail
2012-11-23 Added RELATION is a GO:0071560 (cellular response to transforming growth factor beta stimulus)
2008-04-01 Updated RELATION is a GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway)
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