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GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway

Term Information

ID GO:0007169
Name transmembrane receptor protein tyrosine kinase signaling pathway
Ontology Biological Process
Definition A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
GONUTS GO:0007169 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact transmembrane receptor protein tyrosine kinase signalling pathway

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR001426
InterPro IPR001824
InterPro IPR002011
InterPro IPR006211
InterPro IPR009134
InterPro IPR016243
InterPro IPR016244
InterPro IPR016245
InterPro IPR016246
InterPro IPR016247
InterPro IPR016257
InterPro IPR018941
InterPro IPR020446
InterPro IPR020455
InterPro IPR020461
InterPro IPR020766
InterPro IPR020777
InterPro IPR028792

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0005066 transmembrane receptor protein tyrosine kinase signaling protein activity CONSIDER GO:0007169

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007169:
Relationship To GO:0007169 Child Term Child Term Name
Is a GO:0038109 Kit signaling pathway
Is a GO:0031547 brain-derived neurotrophic factor receptor signaling pathway
Part of GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity
Is a GO:0048008 platelet-derived growth factor receptor signaling pathway
Is a GO:0048009 insulin-like growth factor receptor signaling pathway
Is a GO:0048010 vascular endothelial growth factor receptor signaling pathway
Is a GO:0048011 neurotrophin TRK receptor signaling pathway
Is a GO:0048012 hepatocyte growth factor receptor signaling pathway
Is a GO:0048013 ephrin receptor signaling pathway
Is a GO:0048014 Tie signaling pathway
Is a GO:0008286 insulin receptor signaling pathway
Is a GO:0008293 torso signaling pathway
Is a GO:0008543 fibroblast growth factor receptor signaling pathway
Is a GO:0045500 sevenless signaling pathway
Part of GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
Is a GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway
Is a GO:0060396 growth hormone receptor signaling pathway
Is a GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway
Is a GO:0038084 vascular endothelial growth factor signaling pathway
Is a GO:0038127 ERBB signaling pathway

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007169. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007169 based on the entire annotation set Co-occurrence statistics for GO:0007169 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-01-18 Deleted DEFINITION The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
2012-01-18 Added DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
2008-04-01 Updated RELATION is a GO:0007167 (enzyme linked receptor protein signaling pathway)
2007-08-09 Added SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2007-08-09 Deleted SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2004-04-19 Added SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2004-04-16 Deleted SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2003-11-13 Added SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2002-11-27 Added DEFINITION The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
2002-02-06 Updated TERM transmembrane receptor protein tyrosine kinase signaling pathway
2001-04-03 Updated TERM transmembrane receptor protein tyrosine kinase signaling pathway
2001-03-30 Added TERM transmembrane receptor protein tyrosine kinase signaling pathway

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM transmembrane receptor protein tyrosine kinase signaling pathway
2001-04-03 Updated TERM transmembrane receptor protein tyrosine kinase signaling pathway
2001-03-30 Added TERM transmembrane receptor protein tyrosine kinase signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2012-01-18 Deleted DEFINITION The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
2012-01-18 Added DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
2007-08-09 Added SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2007-08-09 Deleted SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2004-04-19 Added SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2004-04-16 Deleted SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2003-11-13 Added SYNONYM transmembrane receptor protein tyrosine kinase signalling pathway
2002-11-27 Added DEFINITION The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0007167 (enzyme linked receptor protein signaling pathway)
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