spacer

GO:0007094 mitotic spindle assembly checkpoint

Term Information

ID GO:0007094
Name mitotic spindle assembly checkpoint
Ontology Biological Process
Definition A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
PMID:12360190
GONUTS GO:0007094 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow Mad2-dependent checkpoint
exact mitotic cell cycle spindle assembly checkpoint

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
cell cycleLink

Cross-references

Database ID
InterPro IPR008672
InterPro IPR026231
InterPro IPR027097

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007094:
Relationship To GO:0007094 Child Term Child Term Name
Part of GO:0072478 detection of stimulus involved in mitotic spindle assembly checkpoint
Part of GO:0072480 signal transduction involved in mitotic spindle assembly checkpoint
Regulates GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint
Positively regulates GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint
Negatively regulates GO:1902426 negative regulation of mitotic spindle assembly checkpoint
Part of GO:1901925 negative regulation of protein import into nucleus during spindle assembly checkpoint

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007094. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007094 based on the entire annotation set Co-occurrence statistics for GO:0007094 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-09-19 Deleted RELATION is a GO:0022402 (cell cycle process)
2013-05-09 Added RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2013-05-09 Added RELATION is a GO:0022402 (cell cycle process)
2013-04-26 Deleted RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2013-03-22 Deleted SYNONYM negative regulation of mitotic metaphase/anaphase transition by spindle assembly checkpoint
2013-03-11 Deleted RELATION is a GO:0022402 (cell cycle process)
2013-03-03 Added SYNONYM mitotic cell cycle spindle assembly checkpoint
2013-03-03 Updated TERM mitotic spindle assembly checkpoint
2013-01-25 Added RELATION is a GO:0022402 (cell cycle process)
2012-10-31 Added RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2012-10-29 Deleted RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2010-12-10 Added DEFINITION A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
2010-12-10 Deleted DEFINITION A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly).
2010-03-16 Deleted RELATION is a GO:0007093 (mitotic cell cycle checkpoint)
2010-03-16 Added SYNONYM negative regulation of mitotic metaphase/anaphase transition by spindle assembly checkpoint
2009-11-24 Deleted SYNONYM mitotic spindle checkpoint
2009-11-24 Added RELATION is a GO:0071174 (mitotic spindle checkpoint)
2009-11-24 Added RELATION is a GO:0071173 (spindle assembly checkpoint)
2009-11-24 Deleted RELATION is a GO:0031577 (spindle checkpoint)
2009-05-03 Added RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2008-05-13 Added DEFINITION A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly).
2008-05-12 Deleted DEFINITION A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly).
2008-04-01 Updated RELATION is a GO:0007093 (mitotic cell cycle checkpoint)
2008-04-01 Updated RELATION is a GO:0031577 (spindle checkpoint)
2007-08-09 Added SYNONYM Mad2-dependent checkpoint
2007-08-09 Added SYNONYM mitotic spindle checkpoint
2007-08-09 Deleted SYNONYM mitotic spindle checkpoint
2007-08-09 Deleted SYNONYM Mad2-dependent checkpoint
2007-07-02 Added SYNONYM mitotic spindle checkpoint
2007-07-02 Updated TERM mitotic cell cycle spindle assembly checkpoint
2005-10-02 Added SYNONYM Mad2-dependent checkpoint
2004-04-28 Added DEFINITION A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly).
2002-02-06 Updated TERM mitotic spindle checkpoint
2001-04-03 Updated TERM mitotic spindle checkpoint
2001-03-30 Added TERM mitotic spindle checkpoint

Term

Timestamp Action Category Detail
2013-03-03 Updated TERM mitotic spindle assembly checkpoint
2007-07-02 Updated TERM mitotic cell cycle spindle assembly checkpoint
2002-02-06 Updated TERM mitotic spindle checkpoint
2001-04-03 Updated TERM mitotic spindle checkpoint
2001-03-30 Added TERM mitotic spindle checkpoint

Definition/synonyms

Timestamp Action Category Detail
2013-03-22 Deleted SYNONYM negative regulation of mitotic metaphase/anaphase transition by spindle assembly checkpoint
2013-03-03 Added SYNONYM mitotic cell cycle spindle assembly checkpoint
2010-12-10 Added DEFINITION A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
2010-12-10 Deleted DEFINITION A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly).
2010-03-16 Added SYNONYM negative regulation of mitotic metaphase/anaphase transition by spindle assembly checkpoint
2009-11-24 Deleted SYNONYM mitotic spindle checkpoint
2008-05-13 Added DEFINITION A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly).
2008-05-12 Deleted DEFINITION A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly).
2007-08-09 Added SYNONYM Mad2-dependent checkpoint
2007-08-09 Added SYNONYM mitotic spindle checkpoint
2007-08-09 Deleted SYNONYM mitotic spindle checkpoint
2007-08-09 Deleted SYNONYM Mad2-dependent checkpoint
2007-07-02 Added SYNONYM mitotic spindle checkpoint
2005-10-02 Added SYNONYM Mad2-dependent checkpoint
2004-04-28 Added DEFINITION A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly).

Relationships

Timestamp Action Category Detail
2013-09-19 Deleted RELATION is a GO:0022402 (cell cycle process)
2013-05-09 Added RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2013-05-09 Added RELATION is a GO:0022402 (cell cycle process)
2013-04-26 Deleted RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2013-03-11 Deleted RELATION is a GO:0022402 (cell cycle process)
2013-01-25 Added RELATION is a GO:0022402 (cell cycle process)
2012-10-31 Added RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2012-10-29 Deleted RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2010-03-16 Deleted RELATION is a GO:0007093 (mitotic cell cycle checkpoint)
2009-11-24 Added RELATION is a GO:0071174 (mitotic spindle checkpoint)
2009-11-24 Added RELATION is a GO:0071173 (spindle assembly checkpoint)
2009-11-24 Deleted RELATION is a GO:0031577 (spindle checkpoint)
2009-05-03 Added RELATION is a GO:0045841 (negative regulation of mitotic metaphase/anaphase transition)
2008-04-01 Updated RELATION is a GO:0007093 (mitotic cell cycle checkpoint)
2008-04-01 Updated RELATION is a GO:0031577 (spindle checkpoint)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
13ms