spacer

GO:0007026 negative regulation of microtubule depolymerization

Term Information

ID GO:0007026
Name negative regulation of microtubule depolymerization
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
GONUTS GO:0007026 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact downregulation of microtubule depolymerization
narrow inhibition of microtubule depolymerization
exact microtubule stabilization
exact down-regulation of microtubule depolymerization
exact down regulation of microtubule depolymerization
narrow microtubule rescue
narrow negative regulation of microtubule catastrophe
exact negative regulation of microtubule disassembly

Cross-references

Database ID
InterPro IPR026836

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007026:
Relationship To GO:0007026 Child Term Child Term Name
Is a GO:0007027 negative regulation of axonemal microtubule depolymerization
Is a GO:0043146 spindle stabilization
Is a GO:0032932 negative regulation of astral microtubule depolymerization

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007026. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007026 based on the entire annotation set Co-occurrence statistics for GO:0007026 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-02-08 Deleted RELATION is a GO:0043242 (negative regulation of protein complex disassembly)
2013-02-08 Added RELATION is a GO:1901880 (negative regulation of protein depolymerization)
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2009-11-24 Deleted RELATION is a GO:0032269 (negative regulation of cellular protein metabolic process)
2009-03-26 Added SYNONYM negative regulation of microtubule catastrophe
2009-03-26 Added SYNONYM microtubule rescue
2008-10-21 Added RELATION is a GO:0043242 (negative regulation of protein complex disassembly)
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2008-04-01 Updated RELATION is a GO:0032269 (negative regulation of cellular protein metabolic process)
2008-04-01 Updated RELATION is a GO:0031114 (regulation of microtubule depolymerization)
2008-04-01 Added RELATION negatively regulates GO:0007019 (microtubule depolymerization)
2008-04-01 Updated RELATION is a GO:0031111 (negative regulation of microtubule polymerization or depolymerization)
2007-08-09 Added SYNONYM down regulation of microtubule depolymerization
2007-08-09 Added SYNONYM down-regulation of microtubule depolymerization
2007-08-09 Added SYNONYM downregulation of microtubule depolymerization
2007-08-09 Added SYNONYM inhibition of microtubule depolymerization
2007-08-09 Added SYNONYM microtubule stabilization
2007-08-09 Added SYNONYM negative regulation of microtubule disassembly
2007-08-09 Deleted SYNONYM down regulation of microtubule depolymerization
2007-08-09 Deleted SYNONYM down-regulation of microtubule depolymerization
2007-08-09 Deleted SYNONYM downregulation of microtubule depolymerization
2007-08-09 Deleted SYNONYM inhibition of microtubule depolymerization
2007-08-09 Deleted SYNONYM microtubule stabilization
2007-08-09 Deleted SYNONYM negative regulation of microtubule disassembly
2007-02-23 Added SYNONYM down regulation of microtubule depolymerization
2007-02-23 Added SYNONYM down-regulation of microtubule depolymerization
2007-02-23 Added SYNONYM downregulation of microtubule depolymerization
2007-02-23 Added SYNONYM inhibition of microtubule depolymerization
2007-02-16 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-09-29 Added SYNONYM negative regulation of microtubule disassembly
2005-01-20 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-19 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-17 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-16 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-15 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-14 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-13 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-12 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-11 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-10 Updated TERM negative regulation of microtubule depolymerization
2005-01-10 Added SYNONYM microtubule stabilization
2004-03-13 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2003-10-18 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (eg. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2003-04-24 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e. g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2002-02-06 Updated TERM microtubule stabilization
2001-08-06 Added DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2001-04-03 Updated TERM microtubule stabilization
2001-03-30 Added TERM microtubule stabilization

Term

Timestamp Action Category Detail
2005-01-10 Updated TERM negative regulation of microtubule depolymerization
2002-02-06 Updated TERM microtubule stabilization
2001-04-03 Updated TERM microtubule stabilization
2001-03-30 Added TERM microtubule stabilization

Definition/synonyms

Timestamp Action Category Detail
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2009-03-26 Added SYNONYM negative regulation of microtubule catastrophe
2009-03-26 Added SYNONYM microtubule rescue
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2007-08-09 Added SYNONYM down regulation of microtubule depolymerization
2007-08-09 Added SYNONYM down-regulation of microtubule depolymerization
2007-08-09 Added SYNONYM downregulation of microtubule depolymerization
2007-08-09 Added SYNONYM inhibition of microtubule depolymerization
2007-08-09 Added SYNONYM microtubule stabilization
2007-08-09 Added SYNONYM negative regulation of microtubule disassembly
2007-08-09 Deleted SYNONYM down regulation of microtubule depolymerization
2007-08-09 Deleted SYNONYM down-regulation of microtubule depolymerization
2007-08-09 Deleted SYNONYM downregulation of microtubule depolymerization
2007-08-09 Deleted SYNONYM inhibition of microtubule depolymerization
2007-08-09 Deleted SYNONYM microtubule stabilization
2007-08-09 Deleted SYNONYM negative regulation of microtubule disassembly
2007-02-23 Added SYNONYM down regulation of microtubule depolymerization
2007-02-23 Added SYNONYM down-regulation of microtubule depolymerization
2007-02-23 Added SYNONYM downregulation of microtubule depolymerization
2007-02-23 Added SYNONYM inhibition of microtubule depolymerization
2007-02-16 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-09-29 Added SYNONYM negative regulation of microtubule disassembly
2005-01-20 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-19 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-17 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-16 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-15 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-14 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-13 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-12 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-11 Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-10 Added SYNONYM microtubule stabilization
2004-03-13 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2003-10-18 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (eg. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2003-04-24 Updated DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e. g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2001-08-06 Added DEFINITION Prevention of depolymerization of a microtubule; can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.

Relationships

Timestamp Action Category Detail
2013-02-08 Deleted RELATION is a GO:0043242 (negative regulation of protein complex disassembly)
2013-02-08 Added RELATION is a GO:1901880 (negative regulation of protein depolymerization)
2009-11-24 Deleted RELATION is a GO:0032269 (negative regulation of cellular protein metabolic process)
2008-10-21 Added RELATION is a GO:0043242 (negative regulation of protein complex disassembly)
2008-04-01 Updated RELATION is a GO:0032269 (negative regulation of cellular protein metabolic process)
2008-04-01 Updated RELATION is a GO:0031114 (regulation of microtubule depolymerization)
2008-04-01 Added RELATION negatively regulates GO:0007019 (microtubule depolymerization)
2008-04-01 Updated RELATION is a GO:0031111 (negative regulation of microtubule polymerization or depolymerization)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
14ms