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GO:0007020 microtubule nucleation

Term Information

ID GO:0007020
Name microtubule nucleation
Ontology Biological Process
Definition The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
PMID:12517712
GONUTS GO:0007020 Wiki Page

Cross-references

Database ID
InterPro IPR002454
Wikipedia Microtubule_nucleation

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007020:
Relationship To GO:0007020 Child Term Child Term Name
Regulates GO:0010968 regulation of microtubule nucleation
Is a GO:0030954 astral microtubule nucleation
Is a GO:0051418 microtubule nucleation by microtubule organizing center
Positively regulates GO:0090063 positive regulation of microtubule nucleation
Is a GO:0090221 mitotic spindle-templated microtubule nucleation
Is a GO:0090222 centrosome-templated microtubule nucleation
Is a GO:0090223 chromatin-templated microtubule nucleation
Regulates GO:0090226 regulation of microtubule nucleation by Ran protein signal transduction

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0007020. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0007020 based on the entire annotation set Co-occurrence statistics for GO:0007020 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-08-24 Deleted DEFINITION The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
2014-08-24 Added DEFINITION The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
2014-08-24 Added RELATION part of GO:0046785 (microtubule polymerization)
2009-03-02 Added XREF Wikipedia:Microtubule_nucleation
2008-05-13 Added DEFINITION The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
2008-05-12 Deleted DEFINITION The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
2008-04-01 Updated RELATION is a GO:0000226 (microtubule cytoskeleton organization)
2002-11-27 Updated DEFINITION The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
2002-02-06 Updated TERM microtubule nucleation
2001-08-06 Added DEFINITION The de novo formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs frm a specific site within a cell.
2001-04-03 Updated TERM microtubule nucleation
2001-03-30 Added TERM microtubule nucleation

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM microtubule nucleation
2001-04-03 Updated TERM microtubule nucleation
2001-03-30 Added TERM microtubule nucleation

Definition/synonyms

Timestamp Action Category Detail
2014-08-24 Deleted DEFINITION The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
2014-08-24 Added DEFINITION The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
2008-05-13 Added DEFINITION The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
2008-05-12 Deleted DEFINITION The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
2002-11-27 Updated DEFINITION The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
2001-08-06 Added DEFINITION The de novo formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs frm a specific site within a cell.

Relationships

Timestamp Action Category Detail
2014-08-24 Added RELATION part of GO:0046785 (microtubule polymerization)
2008-04-01 Updated RELATION is a GO:0000226 (microtubule cytoskeleton organization)

Cross-references

Timestamp Action Category Detail
2009-03-02 Added XREF Wikipedia:Microtubule_nucleation
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