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GO:0006986 response to unfolded protein

Term Information

ID GO:0006986
Name response to unfolded protein
Ontology Biological Process
Definition Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
Comment Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to one specific response to the presence of unfolded proteins in the ER.
GONUTS GO:0006986 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related heat shock protein activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Response to guidelinesLink

Cross-references

Database ID
UniProtKB-KW Unfolded protein response

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0003773 heat shock protein activity CONSIDER GO:0006986
GO:0051789 response to protein CONSIDER GO:0006986

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006986:
Relationship To GO:0006986 Child Term Child Term Name
Is a GO:0034620 cellular response to unfolded protein
Is a GO:0002235 detection of unfolded protein

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006986. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006986 based on the entire annotation set Co-occurrence statistics for GO:0006986 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-08-05 Added RELATION is a GO:0035966 (response to topologically incorrect protein)
2011-08-05 Deleted RELATION is a GO:0006950 (response to stress)
2011-08-05 Deleted RELATION is a GO:0051789 (response to protein)
2011-08-05 Deleted RELATION is a GO:0009607 (response to biotic stimulus)
2011-05-08 Added DEFINITION Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2011-05-08 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2008-05-13 Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2008-05-12 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2008-04-01 Updated RELATION is a GO:0006950 (response to stress)
2008-04-01 Updated RELATION is a GO:0009607 (response to biotic stimulus)
2008-04-01 Updated RELATION is a GO:0051789 (response to protein)
2007-08-09 Added SYNONYM heat shock protein activity
2007-08-09 Deleted SYNONYM heat shock protein activity
2005-09-20 Updated DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2005-09-17 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of perception of unfolded proteins.
2005-08-10 Added SYNONYM heat shock protein activity
2003-04-16 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of the presence of unfolded proteins.
2003-03-26 Added DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression etc.) as a result of the presence of unfolded proteins.
2002-07-24 Updated TERM response to unfolded protein
2002-02-06 Updated TERM unfolded protein response
2001-04-03 Updated TERM unfolded protein response
2001-03-30 Added TERM unfolded protein response

Term

Timestamp Action Category Detail
2002-07-24 Updated TERM response to unfolded protein
2002-02-06 Updated TERM unfolded protein response
2001-04-03 Updated TERM unfolded protein response
2001-03-30 Added TERM unfolded protein response

Definition/synonyms

Timestamp Action Category Detail
2011-05-08 Added DEFINITION Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2011-05-08 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2008-05-13 Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2008-05-12 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2007-08-09 Added SYNONYM heat shock protein activity
2007-08-09 Deleted SYNONYM heat shock protein activity
2005-09-20 Updated DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2005-09-17 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of perception of unfolded proteins.
2005-08-10 Added SYNONYM heat shock protein activity
2003-04-16 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of the presence of unfolded proteins.
2003-03-26 Added DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression etc.) as a result of the presence of unfolded proteins.

Relationships

Timestamp Action Category Detail
2011-08-05 Added RELATION is a GO:0035966 (response to topologically incorrect protein)
2011-08-05 Deleted RELATION is a GO:0006950 (response to stress)
2011-08-05 Deleted RELATION is a GO:0051789 (response to protein)
2011-08-05 Deleted RELATION is a GO:0009607 (response to biotic stimulus)
2008-04-01 Updated RELATION is a GO:0006950 (response to stress)
2008-04-01 Updated RELATION is a GO:0009607 (response to biotic stimulus)
2008-04-01 Updated RELATION is a GO:0051789 (response to protein)
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