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GO:0006974 cellular response to DNA damage stimulus

Term Information

ID GO:0006974
Name cellular response to DNA damage stimulus
Ontology Biological Process
Definition Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
Secondary IDs GO:0034984
GONUTS GO:0006974 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact cellular DNA damage response
exact DNA damage response
exact response to genotoxic stress
broad response to DNA damage stimulus

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_yeast169

Cross-references

Database ID
InterPro IPR005227
InterPro IPR012923
InterPro IPR015519
InterPro IPR017335
InterPro IPR019502
InterPro IPR023776
InterPro IPR024140
InterPro IPR026836
InterPro IPR026941
UniProtKB-KW DNA damage

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006974:
Relationship To GO:0006974 Child Term Child Term Name
Is a GO:0097044 histone H3-K56 acetylation in response to DNA damage
Is a GO:0042769 DNA damage response, detection of DNA damage
Is a GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
Is a GO:0000077 DNA damage checkpoint
Is a GO:0006281 DNA repair
Is a GO:0006975 DNA damage induced protein phosphorylation
Is a GO:0031297 replication fork processing
Is a GO:0042770 signal transduction in response to DNA damage
Is a GO:0043247 telomere maintenance in response to DNA damage
Is a GO:1990248 regulation of transcription from RNA polymerase II promoter in response to DNA damage
Regulates GO:2001020 regulation of response to DNA damage stimulus
Negatively regulates GO:2001021 negative regulation of response to DNA damage stimulus
Positively regulates GO:2001022 positive regulation of response to DNA damage stimulus
Part of GO:2000776 histone H4 acetylation involved in response to DNA damage stimulus

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006974. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006974 based on the entire annotation set Co-occurrence statistics for GO:0006974 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-10-23 Added SYNONYM response to DNA damage stimulus
2013-10-23 Deleted SYNONYM cellular response to DNA damage stimulus
2013-10-23 Updated TERM cellular response to DNA damage stimulus
2013-04-18 Updated SLIM goslim_yeast
2011-08-14 Added SLIM goslim_yeast
2011-05-08 Added DEFINITION Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2011-05-08 Deleted DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2010-02-27 Added SECONDARY GO:0034984 (cellular response to DNA damage stimulus)
2010-02-27 Added SYNONYM cellular response to DNA damage stimulus
2010-02-27 Added RELATION is a GO:0033554 (cellular response to stress)
2010-02-27 Deleted RELATION is a GO:0006950 (response to stress)
2010-02-27 Added SYNONYM cellular DNA damage response
2010-02-27 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2010-02-27 Added DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2008-05-13 Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2008-05-12 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2008-05-02 Deleted RELATION is a GO:0050896 (response to stimulus)
2008-04-30 Added RELATION is a GO:0050896 (response to stimulus)
2008-04-30 Deleted RELATION is a GO:0009719 (response to endogenous stimulus)
2008-04-01 Updated RELATION is a GO:0006950 (response to stress)
2008-04-01 Updated RELATION is a GO:0009719 (response to endogenous stimulus)
2007-08-09 Added SYNONYM DNA damage response
2007-08-09 Added SYNONYM response to genotoxic stress
2007-08-09 Deleted SYNONYM response to genotoxic stress
2007-08-09 Deleted SYNONYM DNA damage response
2007-03-12 Added SYNONYM response to genotoxic stress
2005-12-15 Added SYNONYM DNA damage response
2005-09-20 Updated DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2005-09-17 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of perception of, or exposure to, damage to its DNA from environmental insults or errors during metabolism.
2003-06-21 Updated TERM response to DNA damage stimulus
2003-06-21 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of damage to its DNA from environmental insults or errors during metabolism.
2003-04-16 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of damage to its DNA.
2003-03-26 Added DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression etc.) as a result of damage to its DNA.
2002-07-24 Updated TERM response to DNA damage
2002-02-06 Updated TERM DNA damage response
2001-04-03 Updated TERM DNA damage response
2001-03-30 Added TERM DNA damage response

Term

Timestamp Action Category Detail
2013-10-23 Updated TERM cellular response to DNA damage stimulus
2003-06-21 Updated TERM response to DNA damage stimulus
2002-07-24 Updated TERM response to DNA damage
2002-02-06 Updated TERM DNA damage response
2001-04-03 Updated TERM DNA damage response
2001-03-30 Added TERM DNA damage response

Definition/synonyms

Timestamp Action Category Detail
2013-10-23 Added SYNONYM response to DNA damage stimulus
2013-10-23 Deleted SYNONYM cellular response to DNA damage stimulus
2011-05-08 Added DEFINITION Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2011-05-08 Deleted DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2010-02-27 Added SYNONYM cellular response to DNA damage stimulus
2010-02-27 Added SYNONYM cellular DNA damage response
2010-02-27 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2010-02-27 Added DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2008-05-13 Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2008-05-12 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2007-08-09 Added SYNONYM DNA damage response
2007-08-09 Added SYNONYM response to genotoxic stress
2007-08-09 Deleted SYNONYM response to genotoxic stress
2007-08-09 Deleted SYNONYM DNA damage response
2007-03-12 Added SYNONYM response to genotoxic stress
2005-12-15 Added SYNONYM DNA damage response
2005-09-20 Updated DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2005-09-17 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of perception of, or exposure to, damage to its DNA from environmental insults or errors during metabolism.
2003-06-21 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of damage to its DNA from environmental insults or errors during metabolism.
2003-04-16 Updated DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression, etc.) as a result of damage to its DNA.
2003-03-26 Added DEFINITION A change in the state or activity of a cell (in terms of enzyme production, gene expression etc.) as a result of damage to its DNA.

Relationships

Timestamp Action Category Detail
2010-02-27 Added RELATION is a GO:0033554 (cellular response to stress)
2010-02-27 Deleted RELATION is a GO:0006950 (response to stress)
2008-05-02 Deleted RELATION is a GO:0050896 (response to stimulus)
2008-04-30 Added RELATION is a GO:0050896 (response to stimulus)
2008-04-30 Deleted RELATION is a GO:0009719 (response to endogenous stimulus)
2008-04-01 Updated RELATION is a GO:0006950 (response to stress)
2008-04-01 Updated RELATION is a GO:0009719 (response to endogenous stimulus)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_yeast
2011-08-14 Added SLIM goslim_yeast
2010-02-27 Added SECONDARY GO:0034984 (cellular response to DNA damage stimulus)
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