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GO:0006958 complement activation, classical pathway

Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.

Term Information

ID GO:0006958
Name complement activation, classical pathway
Ontology Biological Process
Definition Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.
Comment

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0050896 response to stimulus
GO:0002376 immune system process
GO:0065007 biological regulation
GO:0008152 metabolic process
GO:0009605 response to external stimulus
GO:0043170 macromolecule metabolic process
GO:0044238 primary metabolic process
GO:0050789 regulation of biological process
GO:0006950 response to stress
GO:0006955 immune response
GO:0043283 biopolymer metabolic process
GO:0048518 positive regulation of biological process
GO:0010467 gene expression
GO:0006952 defense response
GO:0009611 response to wounding
GO:0002252 immune effector process
GO:0002682 regulation of immune system process
GO:0048583 regulation of response to stimulus
GO:0002250 adaptive immune response
GO:0006959 humoral immune response
GO:0002443 leukocyte mediated immunity
GO:0019538 protein metabolic process
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0048584 positive regulation of response to stimulus
GO:0006954 inflammatory response
GO:0002449 lymphocyte mediated immunity
GO:0002684 positive regulation of immune system process
GO:0051604 protein maturation
GO:0002526 acute inflammatory response
GO:0016485 protein processing
GO:0050776 regulation of immune response
GO:0019724 B cell mediated immunity
GO:0051605 protein maturation by peptide bond cleavage
GO:0016064 immunoglobulin mediated immune response
GO:0050778 positive regulation of immune response
GO:0002455 humoral immune response mediated by circulating immunoglobulin
GO:0002253 activation of immune response
GO:0002541 activation of plasma proteins involved in acute inflammatory response
GO:0006956 complement activation
GO:0006958 complement activation, classical pathway

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
R GO:0030450 regulation of complement activation, classical pathway
NR GO:0045959 negative regulation of complement activation, classical pathway
PR GO:0045960 positive regulation of complement activation, classical pathway

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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23ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-22-04-02-35
Terminal
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