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GO:0006898 receptor-mediated endocytosisThe uptake of external materials by cells, utilizing receptors to ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
Term Information
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| Type | Synonym |
| exact | receptor mediated endocytosis |
| Database | ID |
| INTERPRO | IPR003543 |
| Wikipedia | Receptor-mediated_endocytosis |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0008150 biological_process | ||||||||||
![]() | GO:0009987 cellular process | |||||||||
![]() | ![]() | GO:0051179 localization | ||||||||
![]() | ![]() | ![]() | GO:0016043 cellular component organization | |||||||
![]() | ![]() | ![]() | ![]() | GO:0051234 establishment of localization | ||||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0016044 membrane organization | |||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0006810 transport | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0010324 membrane invagination | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0016192 vesicle-mediated transport | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0006897 endocytosis | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0006898 receptor-mediated endocytosis |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0031623 receptor internalization |
| I | GO:0019065 receptor mediated endocytosis of virus by host |
| R | GO:0048259 regulation of receptor-mediated endocytosis |
| PR | GO:0048260 positive regulation of receptor-mediated endocytosis |
| NR | GO:0048261 negative regulation of receptor-mediated endocytosis |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-22-04-02-35 |