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GO:0006777 Mo-molybdopterin cofactor biosynthetic process

Term Information

ID GO:0006777
Name Mo-molybdopterin cofactor biosynthetic process
Ontology Biological Process
Definition The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
PMID:22370186 PMID:23201473
GONUTS GO:0006777 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact Moco biosynthetic process
exact Moco biosynthesis
exact Mo-molybdopterin cofactor synthesis
exact Mo-molybdopterin cofactor formation
exact Mo-molybdopterin cofactor anabolism
exact Mo-molybdopterin cofactor biosynthesis
related molybdenum cofactor biosynthetic process

Cross-Ontology Relations

Relation Other Ontology ID Term
has_output CHEBI CHEBI:21437 Mo-molybdopterin cofactor

Cross-references

Database ID
InterPro IPR002820
InterPro IPR003448
InterPro IPR004435
InterPro IPR008284
InterPro IPR010034
InterPro IPR010505
InterPro IPR012245
InterPro IPR012247
InterPro IPR012730
InterPro IPR013482
InterPro IPR013483
InterPro IPR013485
InterPro IPR023045
InterPro IPR028886
InterPro IPR028887
InterPro IPR028888
MetaCyc PWY-5354
UniProtKB-KW Molybdenum cofactor biosynthesis

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006777:
Relationship To GO:0006777 Child Term Child Term Name
Is a GO:1902758 bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process
Is a GO:1902760 Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process
Is a GO:1902756 sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process
Has part GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006777. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006777 based on the entire annotation set Co-occurrence statistics for GO:0006777 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-05-25 Added RELATION is a GO:0019538 (protein metabolic process)
2009-08-06 Deleted RELATION is a GO:0042559 (pteridine-containing compound biosynthetic process)
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2008-04-01 Updated RELATION is a GO:0032324 (molybdopterin cofactor biosynthetic process)
2008-04-01 Updated RELATION is a GO:0042559 (pteridine-containing compound biosynthetic process)
2008-04-01 Updated RELATION is a GO:0019720 (Mo-molybdopterin cofactor metabolic process)
2008-04-01 Updated RELATION is a GO:0009108 (coenzyme biosynthetic process)
2007-08-09 Added SYNONYM Mo-molybdopterin cofactor anabolism
2007-08-09 Added SYNONYM Mo-molybdopterin cofactor biosynthesis
2007-08-09 Added SYNONYM Mo-molybdopterin cofactor formation
2007-08-09 Added SYNONYM Mo-molybdopterin cofactor synthesis
2007-08-09 Added SYNONYM Moco biosynthesis
2007-08-09 Added SYNONYM Moco biosynthetic process
2007-08-09 Added SYNONYM molybdenum cofactor biosynthetic process
2007-08-09 Deleted SYNONYM molybdenum cofactor biosynthetic process
2007-08-09 Deleted SYNONYM Mo-molybdopterin cofactor biosynthesis
2007-08-09 Deleted SYNONYM Moco biosynthetic process
2007-08-09 Deleted SYNONYM Mo-molybdopterin cofactor anabolism
2007-08-09 Deleted SYNONYM Mo-molybdopterin cofactor formation
2007-08-09 Deleted SYNONYM Mo-molybdopterin cofactor synthesis
2007-08-09 Deleted SYNONYM Moco biosynthesis
2007-06-28 Added XREF MetaCyc:PWY-5354
2007-06-28 Added SYNONYM molybdenum cofactor biosynthetic process
2007-01-15 Updated TERM Mo-molybdopterin cofactor biosynthetic process
2007-01-15 Added SYNONYM Mo-molybdopterin cofactor biosynthesis
2007-01-15 Added SYNONYM Moco biosynthetic process
2006-10-02 Deleted SYNONYM molybdopterin cofactor biosynthesis
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2005-12-05 Added SYNONYM Moco biosynthesis
2005-12-03 Updated DEFINITION The formation from simpler components of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2005-08-10 Added SYNONYM Mo-molybdopterin cofactor anabolism
2005-08-10 Added SYNONYM Mo-molybdopterin cofactor formation
2005-08-10 Added SYNONYM Mo-molybdopterin cofactor synthesis
2004-10-08 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase.
2004-04-19 Added SYNONYM molybdopterin cofactor biosynthesis
2004-04-16 Deleted SYNONYM molybdopterin cofactor biosynthesis
2004-03-13 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyranopterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +4 and +6 oxidation states. The formation from simpler components of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, Archaea and eukaryotes.
2003-10-18 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, eg. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyranopterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +4 and +6 oxidation states. The formation from simpler components of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, Archaea and eukaryotes.
2003-04-24 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e. g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyranopterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +4 and +6 oxidation states. The formation from simpler components of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, Archaea and eukaryotes.
2002-11-27 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyranopterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +4 and +6 oxidation states. The formation from simpler components of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, Archaea and eukaryotes.
2002-02-15 Added SYNONYM molybdopterin cofactor biosynthesis
2002-02-15 Updated TERM Mo-molybdopterin cofactor biosynthesis
2002-02-06 Updated TERM molybdopterin cofactor biosynthesis
2001-08-06 Added DEFINITION The synthesis of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyrano-pterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +IV and +VI oxidation states. Biosynthesis of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, archaea and eukaryotes.
2001-04-03 Updated TERM molybdopterin cofactor biosynthesis
2001-03-30 Added TERM molybdopterin cofactor biosynthesis

Term

Timestamp Action Category Detail
2007-01-15 Updated TERM Mo-molybdopterin cofactor biosynthetic process
2002-02-15 Updated TERM Mo-molybdopterin cofactor biosynthesis
2002-02-06 Updated TERM molybdopterin cofactor biosynthesis
2001-04-03 Updated TERM molybdopterin cofactor biosynthesis
2001-03-30 Added TERM molybdopterin cofactor biosynthesis

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2007-08-09 Added SYNONYM Mo-molybdopterin cofactor anabolism
2007-08-09 Added SYNONYM Mo-molybdopterin cofactor biosynthesis
2007-08-09 Added SYNONYM Mo-molybdopterin cofactor formation
2007-08-09 Added SYNONYM Mo-molybdopterin cofactor synthesis
2007-08-09 Added SYNONYM Moco biosynthesis
2007-08-09 Added SYNONYM Moco biosynthetic process
2007-08-09 Added SYNONYM molybdenum cofactor biosynthetic process
2007-08-09 Deleted SYNONYM molybdenum cofactor biosynthetic process
2007-08-09 Deleted SYNONYM Mo-molybdopterin cofactor biosynthesis
2007-08-09 Deleted SYNONYM Moco biosynthetic process
2007-08-09 Deleted SYNONYM Mo-molybdopterin cofactor anabolism
2007-08-09 Deleted SYNONYM Mo-molybdopterin cofactor formation
2007-08-09 Deleted SYNONYM Mo-molybdopterin cofactor synthesis
2007-08-09 Deleted SYNONYM Moco biosynthesis
2007-06-28 Added SYNONYM molybdenum cofactor biosynthetic process
2007-01-15 Added SYNONYM Mo-molybdopterin cofactor biosynthesis
2007-01-15 Added SYNONYM Moco biosynthetic process
2006-10-02 Deleted SYNONYM molybdopterin cofactor biosynthesis
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2005-12-05 Added SYNONYM Moco biosynthesis
2005-12-03 Updated DEFINITION The formation from simpler components of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2005-08-10 Added SYNONYM Mo-molybdopterin cofactor anabolism
2005-08-10 Added SYNONYM Mo-molybdopterin cofactor formation
2005-08-10 Added SYNONYM Mo-molybdopterin cofactor synthesis
2004-10-08 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase.
2004-04-19 Added SYNONYM molybdopterin cofactor biosynthesis
2004-04-16 Deleted SYNONYM molybdopterin cofactor biosynthesis
2004-03-13 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyranopterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +4 and +6 oxidation states. The formation from simpler components of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, Archaea and eukaryotes.
2003-10-18 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, eg. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyranopterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +4 and +6 oxidation states. The formation from simpler components of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, Archaea and eukaryotes.
2003-04-24 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e. g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyranopterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +4 and +6 oxidation states. The formation from simpler components of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, Archaea and eukaryotes.
2002-11-27 Updated DEFINITION The formation from simpler components of molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyranopterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +4 and +6 oxidation states. The formation from simpler components of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, Archaea and eukaryotes.
2002-02-15 Added SYNONYM molybdopterin cofactor biosynthesis
2001-08-06 Added DEFINITION The synthesis of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum coordinated by the dithiolene moiety of a family of tricyclic pyrano-pterins containing a cis-dithiolene group in their pyran ring. Enzymes containing a pyranopterin cofactor and either Mo or W are found in all phyla and some of these catalyze important transformations in the global carbon, nitrogen and sulfur cycle. These reactions generally involve redox chemistry at the active site with the metal cycling between the +IV and +VI oxidation states. Biosynthesis of the Mo/W-cofactor is an evolutionarily conserved pathway and genes involved in Moco biosynthesis have been identified in eubacteria, archaea and eukaryotes.

Relationships

Timestamp Action Category Detail
2014-05-25 Added RELATION is a GO:0019538 (protein metabolic process)
2009-08-06 Deleted RELATION is a GO:0042559 (pteridine-containing compound biosynthetic process)
2008-04-01 Updated RELATION is a GO:0032324 (molybdopterin cofactor biosynthetic process)
2008-04-01 Updated RELATION is a GO:0042559 (pteridine-containing compound biosynthetic process)
2008-04-01 Updated RELATION is a GO:0019720 (Mo-molybdopterin cofactor metabolic process)
2008-04-01 Updated RELATION is a GO:0009108 (coenzyme biosynthetic process)

Cross-references

Timestamp Action Category Detail
2007-06-28 Added XREF MetaCyc:PWY-5354
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