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GO:0006749 glutathione metabolic process
Term Information
| ID |
GO:0006749 |
| Name |
glutathione metabolic process |
| Ontology |
Biological Process |
| Definition |
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
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| GONUTS |
GO:0006749 Wiki Page |
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Click on the  icon for more details.
| Type |
Synonym |
| exact |
glutathione metabolism |
| narrow |
oxidized glutathione reduction |
Cross-Ontology Relations
| Relation |
Other Ontology |
ID |
Term |
| has_participant |
CHEBI |
CHEBI:16856 |
glutathione |
Cross-references
| Database |
ID |
| InterPro |
IPR006322 |
| InterPro |
IPR006324 |
Replaces
This term can be used instead of these obsolete terms:
| GO Identifier |
GO Term Name |
Reason |
GO:0006128 |
obsolete oxidized glutathione reduction |
CONSIDER GO:0006749 |
Ancestor Chart
This chart is interactive; you can click on the term boxes and legend for more information.
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006749:
Protein Annotation
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated with GO:0006749. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Change Log
All changes
| Timestamp |
Action |
Category |
Detail |
| 2010-11-05 |
Deleted |
RELATION |
is a GO:0006732 (coenzyme metabolic process) |
| 2009-07-03 |
Added |
RELATION |
is a GO:0006518 (peptide metabolic process) |
| 2009-07-03 |
Added |
RELATION |
is a GO:0006575 (cellular modified amino acid metabolic process) |
| 2008-05-13 |
Added |
DEFINITION |
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2008-05-12 |
Deleted |
DEFINITION |
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2008-04-01 |
Updated |
RELATION |
is a GO:0006732 (coenzyme metabolic process) |
| 2008-04-01 |
Updated |
RELATION |
is a GO:0006790 (sulfur compound metabolic process) |
| 2007-08-09 |
Added |
SYNONYM |
glutathione metabolism |
| 2007-08-09 |
Added |
SYNONYM |
oxidized glutathione reduction |
| 2007-08-09 |
Deleted |
SYNONYM |
glutathione metabolism |
| 2007-08-09 |
Deleted |
SYNONYM |
oxidized glutathione reduction |
| 2007-01-29 |
Added |
SYNONYM |
glutathione metabolism |
| 2007-01-15 |
Updated |
TERM |
glutathione metabolic process |
| 2006-05-04 |
Updated |
DEFINITION |
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2005-08-10 |
Added |
SYNONYM |
oxidized glutathione reduction |
| 2005-01-21 |
Updated |
DEFINITION |
The chemical reactions involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2003-10-23 |
Updated |
DEFINITION |
The chemical reactions and physical changes involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2002-11-27 |
Added |
DEFINITION |
The chemical reactions and physical changes involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2002-02-06 |
Updated |
TERM |
glutathione metabolism |
| 2001-04-03 |
Updated |
TERM |
glutathione metabolism |
| 2001-03-30 |
Added |
TERM |
glutathione metabolism |
Term
| Timestamp |
Action |
Category |
Detail |
| 2007-01-15 |
Updated |
TERM |
glutathione metabolic process |
| 2002-02-06 |
Updated |
TERM |
glutathione metabolism |
| 2001-04-03 |
Updated |
TERM |
glutathione metabolism |
| 2001-03-30 |
Added |
TERM |
glutathione metabolism |
Definition/synonyms
| Timestamp |
Action |
Category |
Detail |
| 2008-05-13 |
Added |
DEFINITION |
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2008-05-12 |
Deleted |
DEFINITION |
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2007-08-09 |
Added |
SYNONYM |
glutathione metabolism |
| 2007-08-09 |
Added |
SYNONYM |
oxidized glutathione reduction |
| 2007-08-09 |
Deleted |
SYNONYM |
glutathione metabolism |
| 2007-08-09 |
Deleted |
SYNONYM |
oxidized glutathione reduction |
| 2007-01-29 |
Added |
SYNONYM |
glutathione metabolism |
| 2006-05-04 |
Updated |
DEFINITION |
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2005-08-10 |
Added |
SYNONYM |
oxidized glutathione reduction |
| 2005-01-21 |
Updated |
DEFINITION |
The chemical reactions involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2003-10-23 |
Updated |
DEFINITION |
The chemical reactions and physical changes involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| 2002-11-27 |
Added |
DEFINITION |
The chemical reactions and physical changes involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
Relationships
| Timestamp |
Action |
Category |
Detail |
| 2010-11-05 |
Deleted |
RELATION |
is a GO:0006732 (coenzyme metabolic process) |
| 2009-07-03 |
Added |
RELATION |
is a GO:0006518 (peptide metabolic process) |
| 2009-07-03 |
Added |
RELATION |
is a GO:0006575 (cellular modified amino acid metabolic process) |
| 2008-04-01 |
Updated |
RELATION |
is a GO:0006732 (coenzyme metabolic process) |
| 2008-04-01 |
Updated |
RELATION |
is a GO:0006790 (sulfur compound metabolic process) |
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14ms
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