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GO:0006749 glutathione metabolic process

The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.

Term Information

ID GO:0006749
Name glutathione metabolic process
Ontology Biological Process
Definition The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
Comment

Synonyms

Type Synonym
exact glutathione metabolism
narrow oxidized glutathione reduction

Cross-references associated with this term:

Database ID
INTERPRO IPR006322
INTERPRO IPR006324

This term can be used instead of these obsolete terms:

GO:0006128 oxidized glutathione reduction (consider GO:0006749)

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0044238 primary metabolic process
GO:0044237 cellular metabolic process
GO:0006518 peptide metabolic process
GO:0006790 sulfur metabolic process
GO:0051186 cofactor metabolic process
GO:0006519 cellular amino acid and derivative metabolic process
GO:0006732 coenzyme metabolic process
GO:0006575 cellular amino acid derivative metabolic process
GO:0006749 glutathione metabolic process

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0006750 glutathione biosynthetic process
I GO:0006751 glutathione catabolic process
I GO:0033355 ascorbate glutathione cycle

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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