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GO:0006621 protein retention in ER lumen

Term Information

ID GO:0006621
Name protein retention in ER lumen
Ontology Biological Process
Definition The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
PMID:12972550
GONUTS GO:0006621 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad maintenance of protein location in ER lumen

Cross-references

Database ID
InterPro IPR000133

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006621:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006621. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006621 based on the entire annotation set Co-occurrence statistics for GO:0006621 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-04-11 Deleted SYNONYM protein-endoplasmic reticulum retention
2010-04-11 Deleted SYNONYM retention of protein in endoplasmic reticulum
2010-04-11 Deleted SYNONYM protein-ER retention
2010-04-11 Deleted SYNONYM retention of protein in ER
2010-04-11 Added RELATION is a GO:0035437 (maintenance of protein localization in endoplasmic reticulum)
2010-04-11 Deleted RELATION is a GO:0032507 (maintenance of protein location in cell)
2008-05-30 Added SYNONYM maintenance of protein location in ER lumen
2008-05-13 Updated TERM protein retention in ER lumen
2008-05-13 Added DEFINITION The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
2008-05-12 Deleted DEFINITION The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
2008-05-09 Deleted RELATION is a GO:0045185 (maintenance of protein location)
2008-04-01 Updated RELATION is a GO:0032507 (maintenance of protein location in cell)
2008-04-01 Updated RELATION is a GO:0045185 (maintenance of protein location)
2007-08-09 Added SYNONYM protein-ER retention
2007-08-09 Added SYNONYM protein-endoplasmic reticulum retention
2007-08-09 Added SYNONYM retention of protein in ER
2007-08-09 Added SYNONYM retention of protein in endoplasmic reticulum
2007-08-09 Deleted SYNONYM protein-ER retention
2007-08-09 Deleted SYNONYM protein-endoplasmic reticulum retention
2007-08-09 Deleted SYNONYM retention of protein in ER
2007-08-09 Deleted SYNONYM retention of protein in endoplasmic reticulum
2005-07-05 Added SYNONYM protein-ER retention
2005-07-05 Added SYNONYM retention of protein in ER
2005-07-05 Added SYNONYM retention of protein in endoplasmic reticulum
2005-07-05 Updated TERM protein retention in ER
2004-11-09 Added SYNONYM protein-endoplasmic reticulum retention
2004-04-25 Updated DEFINITION The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
2004-03-24 Updated DEFINITION The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. KDEL receptors retrieve proteins with the KDEL recognition sequence that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
2002-12-17 Updated TERM protein-ER retention
2002-11-27 Added DEFINITION The retention in the ER lumen of soluble resident proteins. KDEL receptors retrieve proteins with the KDEL recognition sequence that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
2002-02-06 Updated TERM ER retention
2001-04-03 Updated TERM ER retention
2001-03-30 Added TERM ER retention

Term

Timestamp Action Category Detail
2008-05-13 Updated TERM protein retention in ER lumen
2005-07-05 Updated TERM protein retention in ER
2002-12-17 Updated TERM protein-ER retention
2002-02-06 Updated TERM ER retention
2001-04-03 Updated TERM ER retention
2001-03-30 Added TERM ER retention

Definition/synonyms

Timestamp Action Category Detail
2010-04-11 Deleted SYNONYM protein-endoplasmic reticulum retention
2010-04-11 Deleted SYNONYM retention of protein in endoplasmic reticulum
2010-04-11 Deleted SYNONYM protein-ER retention
2010-04-11 Deleted SYNONYM retention of protein in ER
2008-05-30 Added SYNONYM maintenance of protein location in ER lumen
2008-05-13 Added DEFINITION The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
2008-05-12 Deleted DEFINITION The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
2007-08-09 Added SYNONYM protein-ER retention
2007-08-09 Added SYNONYM protein-endoplasmic reticulum retention
2007-08-09 Added SYNONYM retention of protein in ER
2007-08-09 Added SYNONYM retention of protein in endoplasmic reticulum
2007-08-09 Deleted SYNONYM protein-ER retention
2007-08-09 Deleted SYNONYM protein-endoplasmic reticulum retention
2007-08-09 Deleted SYNONYM retention of protein in ER
2007-08-09 Deleted SYNONYM retention of protein in endoplasmic reticulum
2005-07-05 Added SYNONYM protein-ER retention
2005-07-05 Added SYNONYM retention of protein in ER
2005-07-05 Added SYNONYM retention of protein in endoplasmic reticulum
2004-11-09 Added SYNONYM protein-endoplasmic reticulum retention
2004-04-25 Updated DEFINITION The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
2004-03-24 Updated DEFINITION The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. KDEL receptors retrieve proteins with the KDEL recognition sequence that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
2002-11-27 Added DEFINITION The retention in the ER lumen of soluble resident proteins. KDEL receptors retrieve proteins with the KDEL recognition sequence that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.

Relationships

Timestamp Action Category Detail
2010-04-11 Added RELATION is a GO:0035437 (maintenance of protein localization in endoplasmic reticulum)
2010-04-11 Deleted RELATION is a GO:0032507 (maintenance of protein location in cell)
2008-05-09 Deleted RELATION is a GO:0045185 (maintenance of protein location)
2008-04-01 Updated RELATION is a GO:0032507 (maintenance of protein location in cell)
2008-04-01 Updated RELATION is a GO:0045185 (maintenance of protein location)
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