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GO:0006621 protein retention in ER lumenThe retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
Term Information
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| Type | Synonym |
| exact | protein-endoplasmic reticulum retention |
| exact | protein-ER retention |
| broad | maintenance of protein location in ER lumen |
| exact | retention of protein in ER |
| exact | retention of protein in endoplasmic reticulum |
| Database | ID |
| INTERPRO | IPR000133 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0008150 biological_process | ||||||||||||
![]() | GO:0065007 biological regulation | |||||||||||
![]() | ![]() | GO:0051179 localization | ||||||||||
![]() | ![]() | ![]() | GO:0009987 cellular process | |||||||||
![]() | ![]() | ![]() | ![]() | GO:0065008 regulation of biological quality | ||||||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0033036 macromolecule localization | |||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0008104 protein localization | ||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0051641 cellular localization | |||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0051235 maintenance of location | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0051651 maintenance of location in cell | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0045185 maintenance of protein location | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0032507 maintenance of protein location in cell | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0006621 protein retention in ER lumen |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-23-04-03-36 |