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GO:0006614 SRP-dependent cotranslational protein targeting to membrane

Term Information

ID GO:0006614
Name SRP-dependent cotranslational protein targeting to membrane
Ontology Biological Process
Definition The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
GONUTS GO:0006614 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact SRP-dependent cotranslational protein-membrane targeting
exact SRP-dependent cotranslational membrane targeting
broad ER translocation

Cross-references

Database ID
InterPro IPR000897
InterPro IPR002778
InterPro IPR003210
InterPro IPR004125
InterPro IPR004390
InterPro IPR004780
InterPro IPR006325
InterPro IPR008832
InterPro IPR009018
InterPro IPR013699
InterPro IPR013822
InterPro IPR022941
InterPro IPR026258
InterPro IPR026270

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006614:
Relationship To GO:0006614 Child Term Child Term Name
Part of GO:0006615 SRP-dependent cotranslational protein targeting to membrane, docking
Part of GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
Part of GO:0006618 SRP-dependent cotranslational protein targeting to membrane, signal sequence processing
Part of GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
Has part GO:0006412 translation

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006614. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006614 based on the entire annotation set Co-occurrence statistics for GO:0006614 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
2008-05-12 Deleted DEFINITION The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
2008-04-01 Updated RELATION is a GO:0006613 (cotranslational protein targeting to membrane)
2008-04-01 Updated RELATION is a GO:0045047 (protein targeting to ER)
2007-08-09 Added SYNONYM ER translocation
2007-08-09 Added SYNONYM SRP-dependent cotranslational membrane targeting
2007-08-09 Added SYNONYM SRP-dependent cotranslational protein-membrane targeting
2007-08-09 Deleted SYNONYM SRP-dependent cotranslational membrane targeting
2007-08-09 Deleted SYNONYM SRP-dependent cotranslational protein-membrane targeting
2007-08-09 Deleted SYNONYM ER translocation
2005-09-29 Updated TERM SRP-dependent cotranslational protein targeting to membrane
2005-09-29 Added SYNONYM SRP-dependent cotranslational protein-membrane targeting
2004-09-19 Added SYNONYM SRP-dependent cotranslational membrane targeting
2004-09-19 Updated TERM SRP-dependent cotranslational protein-membrane targeting
2004-04-19 Added SYNONYM ER translocation
2004-04-16 Deleted SYNONYM ER translocation
2004-03-24 Updated DEFINITION The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
2003-04-29 Updated TERM SRP-dependent cotranslational membrane targeting
2002-11-27 Added DEFINITION The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the ER signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
2002-02-06 Updated TERM SRP-dependent, co-translational membrane targeting
2002-01-25 Added SYNONYM ER translocation
2001-04-03 Updated TERM SRP-dependent, co-translational membrane targeting
2001-03-30 Added TERM SRP-dependent, co-translational membrane targeting

Term

Timestamp Action Category Detail
2005-09-29 Updated TERM SRP-dependent cotranslational protein targeting to membrane
2004-09-19 Updated TERM SRP-dependent cotranslational protein-membrane targeting
2003-04-29 Updated TERM SRP-dependent cotranslational membrane targeting
2002-02-06 Updated TERM SRP-dependent, co-translational membrane targeting
2001-04-03 Updated TERM SRP-dependent, co-translational membrane targeting
2001-03-30 Added TERM SRP-dependent, co-translational membrane targeting

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
2008-05-12 Deleted DEFINITION The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
2007-08-09 Added SYNONYM ER translocation
2007-08-09 Added SYNONYM SRP-dependent cotranslational membrane targeting
2007-08-09 Added SYNONYM SRP-dependent cotranslational protein-membrane targeting
2007-08-09 Deleted SYNONYM SRP-dependent cotranslational membrane targeting
2007-08-09 Deleted SYNONYM SRP-dependent cotranslational protein-membrane targeting
2007-08-09 Deleted SYNONYM ER translocation
2005-09-29 Added SYNONYM SRP-dependent cotranslational protein-membrane targeting
2004-09-19 Added SYNONYM SRP-dependent cotranslational membrane targeting
2004-04-19 Added SYNONYM ER translocation
2004-04-16 Deleted SYNONYM ER translocation
2004-03-24 Updated DEFINITION The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
2002-11-27 Added DEFINITION The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the ER signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
2002-01-25 Added SYNONYM ER translocation

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0006613 (cotranslational protein targeting to membrane)
2008-04-01 Updated RELATION is a GO:0045047 (protein targeting to ER)
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