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GO:0006508 proteolysisThe chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds.
Term Information
GO SlimsThis term is present in the following GO Consortium-maintained GO slims:
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ID
| Type | Synonym |
| exact | peptidolysis |
| narrow | ATP-dependent proteolysis |
Cross-references associated with this term:
| Database | ID |
| INTERPRO | IPR001967 |
| INTERPRO | IPR001969 |
| INTERPRO | IPR000383 |
| INTERPRO | IPR003709 |
| INTERPRO | IPR001818 |
| INTERPRO | IPR001847 |
| INTERPRO | IPR008750 |
| INTERPRO | IPR003653 |
| INTERPRO | IPR004635 |
| INTERPRO | IPR008294 |
| INTERPRO | IPR001730 |
| INTERPRO | IPR001733 |
| INTERPRO | IPR001769 |
| INTERPRO | IPR006586 |
| INTERPRO | IPR018202 |
| INTERPRO | IPR008256 |
| INTERPRO | IPR008257 |
| INTERPRO | IPR015567 |
| INTERPRO | IPR013578 |
| INTERPRO | IPR001872 |
| INTERPRO | IPR002884 |
| INTERPRO | IPR002886 |
| INTERPRO | IPR002933 |
| INTERPRO | IPR016526 |
| INTERPRO | IPR006025 |
| INTERPRO | IPR006026 |
| INTERPRO | IPR015469 |
| INTERPRO | IPR009007 |
| INTERPRO | IPR017861 |
| INTERPRO | IPR000787 |
| INTERPRO | IPR000816 |
| INTERPRO | IPR000819 |
| INTERPRO | IPR000834 |
| INTERPRO | IPR000841 |
| INTERPRO | IPR000855 |
| INTERPRO | IPR002870 |
| INTERPRO | IPR003966 |
| INTERPRO | IPR012051 |
| INTERPRO | IPR000755 |
| INTERPRO | IPR001641 |
| INTERPRO | IPR001665 |
| INTERPRO | IPR008252 |
| INTERPRO | IPR015251 |
| INTERPRO | IPR003146 |
| INTERPRO | IPR005075 |
| INTERPRO | IPR005080 |
| INTERPRO | IPR005081 |
| INTERPRO | IPR005317 |
| INTERPRO | IPR005320 |
| INTERPRO | IPR005322 |
| INTERPRO | IPR008357 |
| INTERPRO | IPR014850 |
| INTERPRO | IPR018497 |
| INTERPRO | IPR008268 |
| INTERPRO | IPR008269 |
| INTERPRO | IPR008283 |
| INTERPRO | IPR000905 |
| INTERPRO | IPR000930 |
| INTERPRO | IPR001907 |
| INTERPRO | IPR001915 |
| INTERPRO | IPR001930 |
| INTERPRO | IPR001940 |
| INTERPRO | IPR001948 |
| INTERPRO | IPR000177 |
| INTERPRO | IPR000180 |
| INTERPRO | IPR000199 |
| INTERPRO | IPR000200 |
| INTERPRO | IPR000209 |
| INTERPRO | IPR004106 |
| INTERPRO | IPR004109 |
| INTERPRO | IPR004134 |
| INTERPRO | IPR018215 |
| INTERPRO | IPR018992 |
| INTERPRO | IPR013510 |
| INTERPRO | IPR013661 |
| INTERPRO | IPR002398 |
| INTERPRO | IPR002410 |
| INTERPRO | IPR002467 |
| INTERPRO | IPR002468 |
| INTERPRO | IPR002469 |
| INTERPRO | IPR002470 |
| INTERPRO | IPR002471 |
| INTERPRO | IPR020079 |
| INTERPRO | IPR000710 |
| INTERPRO | IPR000718 |
| INTERPRO | IPR000696 |
| INTERPRO | IPR000642 |
| INTERPRO | IPR000667 |
| INTERPRO | IPR000668 |
| INTERPRO | IPR005151 |
| INTERPRO | IPR005073 |
| INTERPRO | IPR005074 |
| INTERPRO | IPR005314 |
| INTERPRO | IPR007484 |
| INTERPRO | IPR000395 |
| INTERPRO | IPR004438 |
| INTERPRO | IPR008915 |
| INTERPRO | IPR008757 |
| INTERPRO | IPR003111 |
| INTERPRO | IPR004815 |
| INTERPRO | IPR001567 |
| INTERPRO | IPR001570 |
| INTERPRO | IPR004447 |
| INTERPRO | IPR001506 |
| INTERPRO | IPR001539 |
| INTERPRO | IPR001548 |
| INTERPRO | IPR001563 |
| INTERPRO | IPR016294 |
| INTERPRO | IPR011600 |
| INTERPRO | IPR001456 |
| INTERPRO | IPR001461 |
| INTERPRO | IPR001714 |
| INTERPRO | IPR007280 |
| INTERPRO | IPR002704 |
| INTERPRO | IPR002705 |
| INTERPRO | IPR017860 |
| INTERPRO | IPR001577 |
| INTERPRO | IPR001590 |
| INTERPRO | IPR000588 |
| INTERPRO | IPR002540 |
| INTERPRO | IPR015471 |
| INTERPRO | IPR001815 |
| INTERPRO | IPR011163 |
| Wikipedia | Proteolysis |
| INTERPRO | IPR006199 |
| INTERPRO | IPR006200 |
| INTERPRO | IPR011782 |
| INTERPRO | IPR011783 |
| INTERPRO | IPR001096 |
| INTERPRO | IPR001131 |
| INTERPRO | IPR001160 |
| INTERPRO | IPR013016 |
| INTERPRO | IPR016129 |
| INTERPRO | IPR000013 |
| INTERPRO | IPR000036 |
| INTERPRO | IPR000126 |
| INTERPRO | IPR001984 |
| INTERPRO | IPR001995 |
| INTERPRO | IPR018114 |
| INTERPRO | IPR018044 |
| INTERPRO | IPR019103 |
| INTERPRO | IPR005536 |
| INTERPRO | IPR009119 |
| INTERPRO | IPR009120 |
| INTERPRO | IPR015956 |
| INTERPRO | IPR001254 |
| INTERPRO | IPR001261 |
| INTERPRO | IPR001300 |
| INTERPRO | IPR001193 |
| INTERPRO | IPR011165 |
| INTERPRO | IPR011164 |
| INTERPRO | IPR011765 |
| INTERPRO | IPR007863 |
| INTERPRO | IPR017051 |
| INTERPRO | IPR016293 |
| INTERPRO | IPR015352 |
| INTERPRO | IPR014394 |
| INTERPRO | IPR015470 |
| INTERPRO | IPR006746 |
| INTERPRO | IPR000317 |
| INTERPRO | IPR012907 |
| INTERPRO | IPR001767 |
| INTERPRO | IPR008753 |
| INTERPRO | IPR008353 |
| INTERPRO | IPR008758 |
| INTERPRO | IPR004236 |
| INTERPRO | IPR001314 |
| INTERPRO | IPR001316 |
| INTERPRO | IPR001333 |
| INTERPRO | IPR001375 |
| INTERPRO | IPR001384 |
| INTERPRO | IPR001431 |
| INTERPRO | IPR000250 |
| INTERPRO | IPR000280 |
| INTERPRO | IPR002138 |
| INTERPRO | IPR002142 |
| INTERPRO | IPR002169 |
| INTERPRO | IPR000081 |
| INTERPRO | IPR000223 |
| INTERPRO | IPR004387 |
| INTERPRO | IPR012848 |
| INTERPRO | IPR001309 |
| INTERPRO | IPR000169 |
This term can be used instead of these obsolete terms:
 GO:0006510 ATP-dependent proteolysis |
(consider GO:0006508) |
Web service: term information
Use this URI template to access this data as a service:
GTerm?id=termID&format=format
Full details can be found on the QuickGO Web Services page.
Ancestor Chart
Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term.
Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms
by one or more 'relationships'
Chart
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
Ancestor Table
Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0008150 biological_process | ||||||||||
 | GO:0008152 metabolic process | |||||||||
 | | GO:0043170 macromolecule metabolic process | ||||||||
| |  | GO:0044238 primary metabolic process | |||||||
| | | | GO:0009056 catabolic process | ||||||
| | | | | GO:0043283 biopolymer metabolic process | |||||
| | | | | | GO:0009057 macromolecule catabolic process | ||||
| | | |  | | | GO:0019538 protein metabolic process | |||
| | | | | | | | GO:0043285 biopolymer catabolic process | ||
| | | | | | | | | GO:0030163 protein catabolic process | |
| | | | | | | | | | GO:0006508 proteolysis |
Relationship key
| Code | Relationship |
 | part of |
| is a |
 | regulates |
 | +ve regulates |
 | -ve regulates |
Child Terms
All direct descendants (child terms) available for this GO term:
| I | GO:0051603 proteolysis involved in cellular protein catabolic process |
| R | GO:0030162 regulation of proteolysis |
| NR | GO:0045861 negative regulation of proteolysis |
| PR | GO:0045862 positive regulation of proteolysis |
Relationship key
| Code | Relationship |
| P | part of |
| I | is a |
Protein Annotation
Co-occurring Terms
Co-occurrence statistics
This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods.
Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
18ms
Stand-alone
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-20-04-03-08 |
Terminal