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GO:0006506 GPI anchor biosynthetic process

Term Information

ID GO:0006506
Name GPI anchor biosynthetic process
Ontology Biological Process
Definition The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
Secondary IDs GO:0015998
GONUTS GO:0006506 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact GPI anchor biosynthesis
exact glycosylphosphatidylinositol biosynthetic process
exact glycosylphosphatidylinositol biosynthesis
broad GPI/GSI anchor biosynthetic process
broad GPI/GSI anchor biosynthesis
exact GPI anchor synthesis
exact GPI anchor anabolism
exact GPI anchor formation

Cross-Ontology Relations

Relation Other Ontology ID Term
has_output CHEBI CHEBI:24410 glycosylphosphatidylinositol

Cross-references

Database ID
InterPro IPR007070
InterPro IPR007315
InterPro IPR007704
InterPro IPR007720
InterPro IPR009447
InterPro IPR009450
InterPro IPR009580
InterPro IPR009600
InterPro IPR013233
InterPro IPR013234
InterPro IPR017852
InterPro IPR027317
UniProtKB-KW GPI-anchor biosynthesis

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0042080 GPI/GSI anchor biosynthetic process CONSIDER GO:0006506

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006506:
Relationship To GO:0006506 Child Term Child Term Name
Is a GO:0050493 GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine
Is a GO:0018265 GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine
Is a GO:0018266 GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine
Is a GO:0018267 GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine
Is a GO:0018268 GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine
Is a GO:0018269 GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine
Is a GO:0018270 GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine
Part of GO:0016254 preassembly of GPI anchor in ER membrane
Part of GO:0016255 attachment of GPI anchor to protein

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006506. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006506 based on the entire annotation set Co-occurrence statistics for GO:0006506 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-11-02 Added RELATION is a GO:0009247 (glycolipid biosynthetic process)
2011-01-30 Added RELATION is a GO:0006661 (phosphatidylinositol biosynthetic process)
2011-01-30 Deleted RELATION is a GO:0046489 (phosphoinositide biosynthetic process)
2010-10-11 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2010-10-11 Added DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2008-08-05 Deleted RELATION is a GO:0044249 (cellular biosynthetic process)
2008-07-17 Added RELATION is a GO:0044249 (cellular biosynthetic process)
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2008-04-01 Updated RELATION is a GO:0006505 (GPI anchor metabolic process)
2008-04-01 Updated RELATION is a GO:0046489 (phosphoinositide biosynthetic process)
2008-04-01 Updated RELATION is a GO:0006497 (protein lipidation)
2007-08-09 Added SYNONYM GPI anchor anabolism
2007-08-09 Added SYNONYM GPI anchor biosynthesis
2007-08-09 Added SYNONYM GPI anchor formation
2007-08-09 Added SYNONYM GPI anchor synthesis
2007-08-09 Added SYNONYM GPI/GSI anchor biosynthesis
2007-08-09 Added SYNONYM GPI/GSI anchor biosynthetic process
2007-08-09 Added SYNONYM glycosylphosphatidylinositol biosynthesis
2007-08-09 Added SYNONYM glycosylphosphatidylinositol biosynthetic process
2007-08-09 Deleted SYNONYM GPI anchor biosynthesis
2007-08-09 Deleted SYNONYM GPI/GSI anchor biosynthetic process
2007-08-09 Deleted SYNONYM glycosylphosphatidylinositol biosynthetic process
2007-08-09 Deleted SYNONYM GPI anchor anabolism
2007-08-09 Deleted SYNONYM GPI anchor formation
2007-08-09 Deleted SYNONYM GPI anchor synthesis
2007-08-09 Deleted SYNONYM GPI/GSI anchor biosynthesis
2007-08-09 Deleted SYNONYM glycosylphosphatidylinositol biosynthesis
2007-01-15 Updated TERM GPI anchor biosynthetic process
2007-01-15 Added SYNONYM GPI anchor biosynthesis
2007-01-15 Added SYNONYM GPI/GSI anchor biosynthetic process
2007-01-15 Added SYNONYM glycosylphosphatidylinositol biosynthetic process
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2005-08-10 Added SYNONYM GPI anchor anabolism
2005-08-10 Added SYNONYM GPI anchor formation
2005-08-10 Added SYNONYM GPI anchor synthesis
2005-08-10 Added SYNONYM GPI/GSI anchor biosynthesis
2004-04-19 Added SYNONYM glycosylphosphatidylinositol biosynthesis
2004-04-16 Deleted SYNONYM glycosylphosphatidylinositol biosynthesis
2002-11-27 Added DEFINITION The formation from simpler components of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2002-11-02 Added SECONDARY GO:0015998 (glycosylphosphatidylinositol biosynthesis)
2002-11-02 Added SYNONYM glycosylphosphatidylinositol biosynthesis
2002-05-09 Updated TERM GPI anchor biosynthesis
2002-02-06 Updated TERM GPI anchor synthesis
2001-04-03 Updated TERM GPI anchor synthesis
2001-03-30 Added TERM GPI anchor synthesis

Term

Timestamp Action Category Detail
2007-01-15 Updated TERM GPI anchor biosynthetic process
2002-05-09 Updated TERM GPI anchor biosynthesis
2002-02-06 Updated TERM GPI anchor synthesis
2001-04-03 Updated TERM GPI anchor synthesis
2001-03-30 Added TERM GPI anchor synthesis

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2010-10-11 Added DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2007-08-09 Added SYNONYM GPI anchor anabolism
2007-08-09 Added SYNONYM GPI anchor biosynthesis
2007-08-09 Added SYNONYM GPI anchor formation
2007-08-09 Added SYNONYM GPI anchor synthesis
2007-08-09 Added SYNONYM GPI/GSI anchor biosynthesis
2007-08-09 Added SYNONYM GPI/GSI anchor biosynthetic process
2007-08-09 Added SYNONYM glycosylphosphatidylinositol biosynthesis
2007-08-09 Added SYNONYM glycosylphosphatidylinositol biosynthetic process
2007-08-09 Deleted SYNONYM GPI anchor biosynthesis
2007-08-09 Deleted SYNONYM GPI/GSI anchor biosynthetic process
2007-08-09 Deleted SYNONYM glycosylphosphatidylinositol biosynthetic process
2007-08-09 Deleted SYNONYM GPI anchor anabolism
2007-08-09 Deleted SYNONYM GPI anchor formation
2007-08-09 Deleted SYNONYM GPI anchor synthesis
2007-08-09 Deleted SYNONYM GPI/GSI anchor biosynthesis
2007-08-09 Deleted SYNONYM glycosylphosphatidylinositol biosynthesis
2007-01-15 Added SYNONYM GPI anchor biosynthesis
2007-01-15 Added SYNONYM GPI/GSI anchor biosynthetic process
2007-01-15 Added SYNONYM glycosylphosphatidylinositol biosynthetic process
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2005-08-10 Added SYNONYM GPI anchor anabolism
2005-08-10 Added SYNONYM GPI anchor formation
2005-08-10 Added SYNONYM GPI anchor synthesis
2005-08-10 Added SYNONYM GPI/GSI anchor biosynthesis
2004-04-19 Added SYNONYM glycosylphosphatidylinositol biosynthesis
2004-04-16 Deleted SYNONYM glycosylphosphatidylinositol biosynthesis
2002-11-27 Added DEFINITION The formation from simpler components of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2002-11-02 Added SYNONYM glycosylphosphatidylinositol biosynthesis

Relationships

Timestamp Action Category Detail
2012-11-02 Added RELATION is a GO:0009247 (glycolipid biosynthetic process)
2011-01-30 Added RELATION is a GO:0006661 (phosphatidylinositol biosynthetic process)
2011-01-30 Deleted RELATION is a GO:0046489 (phosphoinositide biosynthetic process)
2008-08-05 Deleted RELATION is a GO:0044249 (cellular biosynthetic process)
2008-07-17 Added RELATION is a GO:0044249 (cellular biosynthetic process)
2008-04-01 Updated RELATION is a GO:0006505 (GPI anchor metabolic process)
2008-04-01 Updated RELATION is a GO:0046489 (phosphoinositide biosynthetic process)
2008-04-01 Updated RELATION is a GO:0006497 (protein lipidation)

Other

Timestamp Action Category Detail
2002-11-02 Added SECONDARY GO:0015998 (glycosylphosphatidylinositol biosynthesis)
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