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GO:0006464 cellular protein modification process

Term Information

ID GO:0006464
Name cellular protein modification process
Ontology Biological Process
Definition The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GONUTS GO:0006464 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad protein modification process
related protein tagging activity
related process resulting in protein modification

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_candida89
goslim_generic149
goslim_pir462
goslim_plant100
goslim_aspergillus85

Cross-references

Database ID
InterPro IPR000011
InterPro IPR000127
InterPro IPR000682
InterPro IPR000688
InterPro IPR003142
InterPro IPR004143
InterPro IPR004303
InterPro IPR004344
InterPro IPR004408
InterPro IPR004411
InterPro IPR004449
InterPro IPR004666
InterPro IPR008883
InterPro IPR023533
InterPro IPR027753

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0008638 protein tagging activity CONSIDER GO:0006464
GO:0018314 protein-pyrroloquinoline-quinone linkage REPLACEDBY GO:0006464

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006464:
Relationship To GO:0006464 Child Term Child Term Name
Is a GO:0006486 protein glycosylation
Is a GO:0006497 protein lipidation
Regulates GO:0031399 regulation of protein modification process
Negatively regulates GO:0031400 negative regulation of protein modification process
Positively regulates GO:0031401 positive regulation of protein modification process
Is a GO:0043543 protein acylation
Is a GO:0018193 peptidyl-amino acid modification
Is a GO:0010731 protein glutathionylation
Is a GO:0018032 protein amidation
Is a GO:0018277 protein deamination
Is a GO:0070084 protein initiator methionine removal
Is a GO:0001318 formation of oxidatively modified proteins involved in replicative cell aging
Is a GO:0030923 metal incorporation into metallo-oxygen cluster
Is a GO:0042040 metal incorporation into metallo-molybdopterin complex
Is a GO:0018322 protein tyrosinylation
Is a GO:0008213 protein alkylation
Is a GO:0046944 protein carbamoylation
Is a GO:0008214 protein dealkylation
Is a GO:0031162 sulfur incorporation into metallo-sulfur cluster
Is a GO:0018411 protein glucuronidation
Is a GO:0018126 protein hydroxylation
Is a GO:0070930 trans-translation-dependent protein tagging
Is a GO:0018282 metal incorporation into metallo-sulfur cluster
Is a GO:0051725 protein de-ADP-ribosylation
Is a GO:0018307 enzyme active site formation
Is a GO:0018065 protein-cofactor linkage
Is a GO:0018149 peptide cross-linking
Is a GO:0018079 protein halogenation
Is a GO:0051697 protein delipidation
Is a GO:0032020 ISG15-protein conjugation
Is a GO:0017013 protein flavinylation
Is a GO:0018350 protein esterification
Is a GO:0006477 protein sulfation
Is a GO:0006468 protein phosphorylation
Is a GO:0030047 actin modification
Is a GO:0018214 protein carboxylation
Is a GO:0017006 protein-tetrapyrrole linkage
Is a GO:0016255 attachment of GPI anchor to protein
Is a GO:0018094 protein polyglycylation
Is a GO:0018143 nucleic acid-protein covalent cross-linking
Is a GO:0018298 protein-chromophore linkage
Is a GO:0018180 protein desulfurization
Is a GO:0006470 protein dephosphorylation
Is a GO:0009305 protein biotinylation
Is a GO:0018215 protein phosphopantetheinylation
Is a GO:0018158 protein oxidation
Is a GO:0018175 protein nucleotidylation
Is a GO:0016598 protein arginylation
Is a GO:0016570 histone modification
Is a GO:0017014 protein nitrosylation
Is a GO:0031365 N-terminal protein amino acid modification
Is a GO:0035601 protein deacylation
Is a GO:0080058 protein deglutathionylation
Is a GO:0019988 charged-tRNA amino acid modification
Is a GO:0044524 protein sulfhydration
Is a GO:0006517 protein deglycosylation
Is a GO:0018184 protein polyamination
Is a GO:0043686 co-translational protein modification
Is a GO:0043687 post-translational protein modification
Is a GO:0018249 protein dehydration
Is a GO:0070647 protein modification by small protein conjugation or removal
Is a GO:0044601 protein denucleotidylation
Is a GO:0018342 protein prenylation

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Assigned By
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Name
Synonym
Type
Taxon Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006464. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006464 based on the entire annotation set Co-occurrence statistics for GO:0006464 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_candida
2012-04-28 Updated TERM cellular protein modification process
2012-04-28 Added DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2012-04-28 Deleted DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2012-04-28 Added SYNONYM protein modification process
2012-04-28 Added RELATION is a GO:0036211 (protein modification process)
2012-04-28 Deleted RELATION is a GO:0043412 (macromolecule modification)
2011-11-05 Added SLIM goslim_aspergillus
2011-08-14 Deleted SLIM goslim_yeast
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_generic
2008-06-09 Added SLIM goslim_candida
2008-05-13 Added DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2008-05-12 Deleted DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2008-04-01 Updated RELATION is a GO:0043412 (macromolecule modification)
2008-04-01 Updated RELATION is a GO:0044267 (cellular protein metabolic process)
2007-10-05 Deleted SYNONYM protein-pyrroloquinoline-quinone linkage
2007-08-09 Added SYNONYM process resulting in protein modification
2007-08-09 Added SYNONYM protein tagging activity
2007-08-09 Added SYNONYM protein-pyrroloquinoline-quinone linkage
2007-08-09 Deleted SYNONYM process resulting in protein modification
2007-08-09 Deleted SYNONYM protein tagging activity
2007-08-09 Deleted SYNONYM protein-pyrroloquinoline-quinone linkage
2007-04-20 Updated DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2007-04-01 Updated TERM protein modification process
2007-04-01 Added SYNONYM process resulting in protein modification
2007-02-06 Updated DEFINITION The covalent alteration of one or more amino acids occurring in a protein. This includes pre-translational, co-translational and post-translational modifications.
2006-03-15 Updated DEFINITION The covalent alteration of one or more amino acid residues within a protein, resulting in a change in the properties of that protein.
2005-08-10 Added SYNONYM protein tagging activity
2005-08-10 Added SYNONYM protein-pyrroloquinoline-quinone linkage
2005-07-08 Updated DEFINITION The covalent or conformational alteration of one or more amino acid residues within a protein, resulting in a change in the properties of that protein.
2004-03-18 Added DEFINITION The covalent alteration of one or more amino acid residues within a protein, resulting in a change in the properties of that protein.
2002-02-06 Updated TERM protein modification
2001-04-03 Updated TERM protein modification
2001-03-30 Added TERM protein modification

Term

Timestamp Action Category Detail
2012-04-28 Updated TERM cellular protein modification process
2007-04-01 Updated TERM protein modification process
2002-02-06 Updated TERM protein modification
2001-04-03 Updated TERM protein modification
2001-03-30 Added TERM protein modification

Definition/synonyms

Timestamp Action Category Detail
2012-04-28 Added DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2012-04-28 Deleted DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2012-04-28 Added SYNONYM protein modification process
2008-05-13 Added DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2008-05-12 Deleted DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2007-10-05 Deleted SYNONYM protein-pyrroloquinoline-quinone linkage
2007-08-09 Added SYNONYM process resulting in protein modification
2007-08-09 Added SYNONYM protein tagging activity
2007-08-09 Added SYNONYM protein-pyrroloquinoline-quinone linkage
2007-08-09 Deleted SYNONYM process resulting in protein modification
2007-08-09 Deleted SYNONYM protein tagging activity
2007-08-09 Deleted SYNONYM protein-pyrroloquinoline-quinone linkage
2007-04-20 Updated DEFINITION The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
2007-04-01 Added SYNONYM process resulting in protein modification
2007-02-06 Updated DEFINITION The covalent alteration of one or more amino acids occurring in a protein. This includes pre-translational, co-translational and post-translational modifications.
2006-03-15 Updated DEFINITION The covalent alteration of one or more amino acid residues within a protein, resulting in a change in the properties of that protein.
2005-08-10 Added SYNONYM protein tagging activity
2005-08-10 Added SYNONYM protein-pyrroloquinoline-quinone linkage
2005-07-08 Updated DEFINITION The covalent or conformational alteration of one or more amino acid residues within a protein, resulting in a change in the properties of that protein.
2004-03-18 Added DEFINITION The covalent alteration of one or more amino acid residues within a protein, resulting in a change in the properties of that protein.

Relationships

Timestamp Action Category Detail
2012-04-28 Added RELATION is a GO:0036211 (protein modification process)
2012-04-28 Deleted RELATION is a GO:0043412 (macromolecule modification)
2008-04-01 Updated RELATION is a GO:0043412 (macromolecule modification)
2008-04-01 Updated RELATION is a GO:0044267 (cellular protein metabolic process)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_candida
2011-11-05 Added SLIM goslim_aspergillus
2011-08-14 Deleted SLIM goslim_yeast
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_generic
2008-06-09 Added SLIM goslim_candida
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