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GO:0006457 protein folding

The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.

Term Information

ID GO:0006457
Name protein folding
Ontology Biological Process
Definition The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
Comment

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_candida91
goslim_pir470
goslim_pombe48
goslim_yeast93

Synonyms

Type Synonym
narrow chaperonin-mediated tubulin folding
related chaperone activity
narrow beta-tubulin folding
narrow alpha-tubulin folding
related chaperonin ATPase activity
related co-chaperone activity
related co-chaperonin activity
related glycoprotein-specific chaperone activity
related non-chaperonin molecular chaperone ATPase activity
related protein complex assembly, multichaperone pathway

Cross-references associated with this term:

Database ID
Wikipedia Protein_folding
INTERPRO IPR019805
INTERPRO IPR000740
INTERPRO IPR002777
INTERPRO IPR001179
INTERPRO IPR016304
INTERPRO IPR015317
INTERPRO IPR012713
INTERPRO IPR012714
INTERPRO IPR012715
INTERPRO IPR012716
INTERPRO IPR002194
INTERPRO IPR012717
INTERPRO IPR012718
INTERPRO IPR012719
INTERPRO IPR012720
INTERPRO IPR012721
INTERPRO IPR012722
INTERPRO IPR012724
INTERPRO IPR012725
INTERPRO IPR004127
INTERPRO IPR009073
INTERPRO IPR009033
INTERPRO IPR011599
INTERPRO IPR018369
INTERPRO IPR018370
INTERPRO IPR008881
INTERPRO IPR008880
INTERPRO IPR001476
INTERPRO IPR009012
INTERPRO IPR016153
INTERPRO IPR016154
INTERPRO IPR000397
INTERPRO IPR001305
INTERPRO IPR001404
INTERPRO IPR002939
INTERPRO IPR003095
INTERPRO IPR012406
INTERPRO IPR000774
INTERPRO IPR009169
INTERPRO IPR004640
INTERPRO IPR008971
INTERPRO IPR004961

This term can be used instead of these obsolete terms:

GO:0010545 Hsp90 protein regulator activity (consider GO:0006457)
GO:0010546 Hsp90 protein inhibitor activity (consider GO:0006457)
GO:0017078 Hsc70 protein regulator activity (consider GO:0006457)
GO:0030188 chaperone regulator activity (consider GO:0006457)
GO:0030189 chaperone activator activity (consider GO:0006457)
GO:0030190 chaperone inhibitor activity (consider GO:0006457)
GO:0030191 Hsp70/Hsc70 protein inhibitor activity (consider GO:0006457)
GO:0030192 Hsp70/Hsc70 protein regulator activity (consider GO:0006457)
GO:0008571 non-chaperonin molecular chaperone ATPase activity (consider GO:0006457)
GO:0003754 chaperone activity (consider GO:0006457)
GO:0003759 glycoprotein-specific chaperone activity (consider GO:0006457)
GO:0003763 chaperonin ATPase activity (consider GO:0006457)
GO:0003767 co-chaperone activity (consider GO:0006457)
GO:0003772 co-chaperonin activity (consider GO:0006457)
GO:0006462 protein complex assembly, multichaperone pathway (consider GO:0006457)
GO:0010538 Hsp27 protein regulator activity (consider GO:0006457)
GO:0010539 Hsp27 protein inhibitor activity (consider GO:0006457)

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0008152 metabolic process
GO:0009987 cellular process
GO:0043170 macromolecule metabolic process
GO:0044238 primary metabolic process
GO:0044237 cellular metabolic process
GO:0043283 biopolymer metabolic process
GO:0044260 cellular macromolecule metabolic process
GO:0019538 protein metabolic process
GO:0034960 cellular biopolymer metabolic process
GO:0044267 cellular protein metabolic process
GO:0006457 protein folding

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0006458 'de novo' protein folding
I GO:0006467 protein thiol-disulfide exchange
I GO:0042026 protein refolding
I GO:0022417 protein maturation by protein folding
I GO:0034975 protein folding in endoplasmic reticulum
I GO:0007023 post-chaperonin tubulin folding pathway

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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