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GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation

Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.

Term Information

ID GO:0006388
Name tRNA splicing, via endonucleolytic cleavage and ligation
Ontology Biological Process
Definition Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
Comment Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.

Synonyms

Type Synonym
narrow tRNA-Y splicing

Cross-references associated with this term:

Database ID
INTERPRO IPR006678
INTERPRO IPR006677
INTERPRO IPR006676
INTERPRO IPR016589
INTERPRO IPR015965
INTERPRO IPR002745
INTERPRO IPR015968
INTERPRO IPR015966
INTERPRO IPR012387

This term can be used instead of these obsolete terms:

GO:0006389 tRNA-Y splicing (consider GO:0006388)

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Ancestor Table

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0043170 macromolecule metabolic process
GO:0044238 primary metabolic process
GO:0043283 biopolymer metabolic process
GO:0010467 gene expression
GO:0044237 cellular metabolic process
GO:0044260 cellular macromolecule metabolic process
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0034960 cellular biopolymer metabolic process
GO:0016070 RNA metabolic process
GO:0034660 ncRNA metabolic process
GO:0006399 tRNA metabolic process
GO:0006396 RNA processing
GO:0034470 ncRNA processing
GO:0008380 RNA splicing
GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation
GO:0008033 tRNA processing
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
P GO:0000379 tRNA-type intron splice site recognition and cleavage
P GO:0000968 tRNA exon ligation

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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