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GO:0016556 mRNA modification

Term Information

ID GO:0016556
Name mRNA modification
Ontology Biological Process
Definition The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
Comment The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.
Secondary IDs GO:0006381
GONUTS GO:0016556 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow mRNA editing

Cross-references

Database ID
InterPro IPR033111

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016556:
Relationship To GO:0016556 Child Term Child Term Name
Positively regulates GO:0090366 positive regulation of mRNA modification
Regulates GO:0090365 regulation of mRNA modification
Negatively regulates GO:0090367 negative regulation of mRNA modification
Is a GO:0080156 mitochondrial mRNA modification
Is a GO:0080009 mRNA methylation
Is a GO:1990481 mRNA pseudouridine synthesis
Is a GO:1900871 chloroplast mRNA modification
Capable of part of GO:0045293 mRNA editing complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016556. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016556 based on the entire annotation set Co-occurrence statistics for GO:0016556 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-04-16 Added SYNONYM mRNA editing
2010-04-16 Deleted SYNONYM mRNA editing
2008-05-13 Added DEFINITION The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
2008-05-12 Deleted DEFINITION The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
2008-04-01 Updated RELATION is a GO:0009451 (RNA modification)
2008-04-01 Updated RELATION is a GO:0016071 (mRNA metabolic process)
2007-08-09 Added SYNONYM mRNA editing
2007-08-09 Deleted SYNONYM mRNA editing
2007-07-29 Added SECONDARY GO:0006381 (mRNA editing)
2007-07-29 Added SYNONYM mRNA editing
2007-07-27 Updated DEFINITION The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
2006-03-15 Updated DEFINITION The covalent alteration of one or more nucleotides within mRNA, resulting in a change in the properties of the mRNA.
2005-03-16 Added DEFINITION The enzymatic modification of the chemical structure of specific sites in mRNA.
2002-02-06 Updated TERM mRNA modification
2001-04-03 Updated TERM mRNA modification
2001-03-30 Added TERM mRNA modification

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM mRNA modification
2001-04-03 Updated TERM mRNA modification
2001-03-30 Added TERM mRNA modification

Definition/synonyms

Timestamp Action Category Detail
2010-04-16 Added SYNONYM mRNA editing
2010-04-16 Deleted SYNONYM mRNA editing
2008-05-13 Added DEFINITION The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
2008-05-12 Deleted DEFINITION The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
2007-08-09 Added SYNONYM mRNA editing
2007-08-09 Deleted SYNONYM mRNA editing
2007-07-29 Added SYNONYM mRNA editing
2007-07-27 Updated DEFINITION The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
2006-03-15 Updated DEFINITION The covalent alteration of one or more nucleotides within mRNA, resulting in a change in the properties of the mRNA.
2005-03-16 Added DEFINITION The enzymatic modification of the chemical structure of specific sites in mRNA.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0009451 (RNA modification)
2008-04-01 Updated RELATION is a GO:0016071 (mRNA metabolic process)

Other

Timestamp Action Category Detail
2007-07-29 Added SECONDARY GO:0006381 (mRNA editing)
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