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GO:0006352 DNA-templated transcription, initiation

Term Information

ID GO:0006352
Name DNA-templated transcription, initiation
Ontology Biological Process
Definition Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
PMID:18280161
Comment Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.
GONUTS GO:0006352 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related transcription initiation, DNA-dependent
exact DNA-dependent transcription, initiation
related transcription initiation factor activity
exact initiation of transcription, DNA-dependent
exact DNA-dependent RNA polymerase complex assembly at promoter
exact initiation of DNA-dependent transcription

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to transcription processesLink

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_yeast169

Cross-references

Database ID
InterPro IPR000394
InterPro IPR000812
InterPro IPR000814
InterPro IPR000838
InterPro IPR000943
InterPro IPR003162
InterPro IPR003228
InterPro IPR003923
InterPro IPR004343
InterPro IPR004823
InterPro IPR007046
InterPro IPR007624
InterPro IPR007627
InterPro IPR007630
InterPro IPR007631
InterPro IPR007900
InterPro IPR009042
InterPro IPR011177
InterPro IPR012759
InterPro IPR012760
InterPro IPR012761
InterPro IPR012845
InterPro IPR013249
InterPro IPR013324
InterPro IPR013325
InterPro IPR014200
InterPro IPR014209
InterPro IPR014212
InterPro IPR014218
InterPro IPR014236
InterPro IPR014284
InterPro IPR014286
InterPro IPR014293
InterPro IPR014296
InterPro IPR014322
InterPro IPR018144
InterPro IPR028617
InterPro IPR028630

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0016986 transcription initiation factor activity CONSIDER GO:0006352

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006352:
Relationship To GO:0006352 Child Term Child Term Name
Is a GO:0006361 transcription initiation from RNA polymerase I promoter
Is a GO:0006367 transcription initiation from RNA polymerase II promoter
Is a GO:0006384 transcription initiation from RNA polymerase III promoter
Is a GO:0006391 transcription initiation from mitochondrial promoter
Part of GO:0070897 DNA-templated transcriptional preinitiation complex assembly
Part of GO:0001112 DNA-templated transcriptional open complex formation
Is a GO:0001123 transcription initiation from bacterial-type RNA polymerase promoter
Regulates GO:2000142 regulation of DNA-templated transcription, initiation
Negatively regulates GO:2000143 negative regulation of DNA-templated transcription, initiation
Positively regulates GO:2000144 positive regulation of DNA-templated transcription, initiation
Part of GO:0001173 DNA-templated transcriptional start site selection

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
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Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Date
Assigned By
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Name
Synonym
Type
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006352. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006352 based on the entire annotation set Co-occurrence statistics for GO:0006352 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-14 Updated TERM DNA-templated transcription, initiation
2013-12-14 Added SYNONYM DNA-dependent transcription, initiation
2013-04-18 Updated SLIM goslim_yeast
2012-07-10 Updated TERM DNA-dependent transcription, initiation
2012-07-10 Added SYNONYM transcription initiation, DNA-dependent
2012-07-10 Added SYNONYM initiation of DNA-dependent transcription
2011-11-17 Added SYNONYM transcription initiation factor activity
2011-08-14 Added SLIM goslim_yeast
2010-12-16 Added SYNONYM DNA-dependent RNA polymerase complex assembly at promoter
2010-12-16 Deleted SYNONYM RNA polymerase complex assembly at promoter
2010-12-16 Added SYNONYM initiation of transcription, DNA-dependent
2010-12-16 Deleted SYNONYM initiation of transcription
2010-12-16 Updated TERM transcription initiation, DNA-dependent
2010-12-05 Deleted DEFINITION Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
2010-12-05 Added DEFINITION Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
2010-12-05 Added RELATION is a GO:0032774 (RNA biosynthetic process)
2010-12-05 Deleted RELATION is a GO:0006461 (protein complex assembly)
2010-10-06 Added SYNONYM initiation of transcription
2010-09-03 Deleted DEFINITION Any process involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter.
2010-09-03 Added DEFINITION Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
2009-10-29 Added RELATION is a GO:0006461 (protein complex assembly)
2009-10-29 Deleted RELATION is a GO:0032774 (RNA biosynthetic process)
2009-08-31 Added RELATION is a GO:0032774 (RNA biosynthetic process)
2009-08-31 Deleted RELATION is a GO:0065004 (protein-DNA complex assembly)
2008-05-16 Deleted DEFINITION Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter.
2008-05-16 Added DEFINITION Any process involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter.
2008-05-13 Added DEFINITION Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter.
2008-05-12 Deleted DEFINITION Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter.
2008-04-01 Updated RELATION is a GO:0065004 (protein-DNA complex assembly)
2008-04-01 Updated RELATION part of GO:0006351 (transcription, DNA-templated)
2007-08-09 Added SYNONYM RNA polymerase complex assembly at promoter
2007-08-09 Deleted SYNONYM RNA polymerase complex assembly at promoter
2007-01-15 Added SYNONYM RNA polymerase complex assembly at promoter
2007-01-09 Updated DEFINITION Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter.
2003-10-25 Added DEFINITION Processes involved in starting transcription, which is the synthesis of RNA by RNA polymerases using a DNA template.
2002-02-06 Updated TERM transcription initiation
2001-04-03 Updated TERM transcription initiation
2001-03-30 Added TERM transcription initiation

Term

Timestamp Action Category Detail
2013-12-14 Updated TERM DNA-templated transcription, initiation
2012-07-10 Updated TERM DNA-dependent transcription, initiation
2010-12-16 Updated TERM transcription initiation, DNA-dependent
2002-02-06 Updated TERM transcription initiation
2001-04-03 Updated TERM transcription initiation
2001-03-30 Added TERM transcription initiation

Definition/synonyms

Timestamp Action Category Detail
2013-12-14 Added SYNONYM DNA-dependent transcription, initiation
2012-07-10 Added SYNONYM transcription initiation, DNA-dependent
2012-07-10 Added SYNONYM initiation of DNA-dependent transcription
2011-11-17 Added SYNONYM transcription initiation factor activity
2010-12-16 Added SYNONYM DNA-dependent RNA polymerase complex assembly at promoter
2010-12-16 Deleted SYNONYM RNA polymerase complex assembly at promoter
2010-12-16 Added SYNONYM initiation of transcription, DNA-dependent
2010-12-16 Deleted SYNONYM initiation of transcription
2010-12-05 Deleted DEFINITION Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
2010-12-05 Added DEFINITION Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
2010-10-06 Added SYNONYM initiation of transcription
2010-09-03 Deleted DEFINITION Any process involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter.
2010-09-03 Added DEFINITION Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
2008-05-16 Deleted DEFINITION Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter.
2008-05-16 Added DEFINITION Any process involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter.
2008-05-13 Added DEFINITION Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter.
2008-05-12 Deleted DEFINITION Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter.
2007-08-09 Added SYNONYM RNA polymerase complex assembly at promoter
2007-08-09 Deleted SYNONYM RNA polymerase complex assembly at promoter
2007-01-15 Added SYNONYM RNA polymerase complex assembly at promoter
2007-01-09 Updated DEFINITION Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter.
2003-10-25 Added DEFINITION Processes involved in starting transcription, which is the synthesis of RNA by RNA polymerases using a DNA template.

Relationships

Timestamp Action Category Detail
2010-12-05 Added RELATION is a GO:0032774 (RNA biosynthetic process)
2010-12-05 Deleted RELATION is a GO:0006461 (protein complex assembly)
2009-10-29 Added RELATION is a GO:0006461 (protein complex assembly)
2009-10-29 Deleted RELATION is a GO:0032774 (RNA biosynthetic process)
2009-08-31 Added RELATION is a GO:0032774 (RNA biosynthetic process)
2009-08-31 Deleted RELATION is a GO:0065004 (protein-DNA complex assembly)
2008-04-01 Updated RELATION is a GO:0065004 (protein-DNA complex assembly)
2008-04-01 Updated RELATION part of GO:0006351 (transcription, DNA-templated)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_yeast
2011-08-14 Added SLIM goslim_yeast
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