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GO:0006342 chromatin silencing

Term Information

ID GO:0006342
Name chromatin silencing
Ontology Biological Process
Definition Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
PMID:10219245
Comment Note that this process is the opposite of chromatin-mediated maintenance of transcription. This regulation is exemplified by members of the Polycomb group, which maintain the inactive state of homeotic gene transcription.
Secondary IDs GO:0016440
GONUTS GO:0006342 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact TGS
exact chromatin-mediated silencing
exact chromatin-mediated maintenance of transcriptional inactivation
related heterochromatic silencing
exact transcriptional gene silencing

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to transcription processesLink

Cross-references

Database ID
InterPro IPR007654
InterPro IPR021169

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0006339 positive regulation of transcription of homeotic gene (trithorax group) CONSIDER GO:0006342
GO:0006340 negative regulation of transcription of homeotic gene (Polycomb group) CONSIDER GO:0006342
GO:0045888 regulation of transcription of homeotic gene (Polycomb group) CONSIDER GO:0006342
GO:0045889 positive regulation of transcription of homeotic gene (Polycomb group) CONSIDER GO:0006342
GO:0045890 regulation of transcription of homeotic gene (trithorax group) CONSIDER GO:0006342
GO:0045891 negative regulation of transcription of homeotic gene (trithorax group) CONSIDER GO:0006342

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006342:
Relationship To GO:0006342 Child Term Child Term Name
Is a GO:0000183 chromatin silencing at rDNA
Part of GO:0006343 establishment of chromatin silencing
Part of GO:0006344 maintenance of chromatin silencing
Is a GO:0006348 chromatin silencing at telomere
Is a GO:0030702 chromatin silencing at centromere
Regulates GO:0031935 regulation of chromatin silencing
Negatively regulates GO:0031936 negative regulation of chromatin silencing
Positively regulates GO:0031937 positive regulation of chromatin silencing
Is a GO:0006346 methylation-dependent chromatin silencing
Is a GO:0030466 chromatin silencing at silent mating-type cassette
Is a GO:0031048 chromatin silencing by small RNA
Part of GO:0070868 heterochromatin organization involved in chromatin silencing
Is a GO:0061587 transfer RNA gene-mediated silencing

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006342. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006342 based on the entire annotation set Co-occurrence statistics for GO:0006342 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-10-09 Deleted RELATION is a GO:0031507 (heterochromatin assembly)
2008-10-09 Deleted DEFINITION Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
2008-10-09 Added DEFINITION Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
2008-10-09 Deleted SYNONYM heterochromatic silencing
2008-10-09 Added SYNONYM heterochromatic silencing
2008-10-02 Added RELATION is a GO:0031507 (heterochromatin assembly)
2008-09-06 Deleted RELATION is a GO:0031507 (heterochromatin assembly)
2008-05-13 Added DEFINITION Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
2008-05-12 Deleted DEFINITION Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
2008-04-01 Updated RELATION is a GO:0016458 (gene silencing)
2008-04-01 Updated RELATION is a GO:0045892 (negative regulation of transcription, DNA-templated)
2008-04-01 Updated RELATION is a GO:0045814 (negative regulation of gene expression, epigenetic)
2008-04-01 Updated RELATION is a GO:0031507 (heterochromatin assembly)
2007-09-10 Deleted SYNONYM negative regulation of transcription of homeotic gene (Polycomb group)
2007-09-10 Deleted SYNONYM negative regulation of transcription of homeotic gene (trithorax group)
2007-09-10 Deleted SYNONYM positive regulation of transcription of homeotic gene (Polycomb group)
2007-09-10 Deleted SYNONYM positive regulation of transcription of homeotic gene (trithorax group)
2007-09-10 Deleted SYNONYM regulation of transcription of homeotic gene (Polycomb group)
2007-09-10 Deleted SYNONYM regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Added SYNONYM TGS
2007-08-09 Added SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2007-08-09 Added SYNONYM chromatin-mediated silencing
2007-08-09 Added SYNONYM heterochromatic silencing
2007-08-09 Added SYNONYM negative regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Added SYNONYM negative regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Added SYNONYM positive regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Added SYNONYM positive regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Added SYNONYM regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Added SYNONYM regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Added SYNONYM transcriptional gene silencing
2007-08-09 Deleted SYNONYM heterochromatic silencing
2007-08-09 Deleted SYNONYM TGS
2007-08-09 Deleted SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2007-08-09 Deleted SYNONYM chromatin-mediated silencing
2007-08-09 Deleted SYNONYM negative regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Deleted SYNONYM negative regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Deleted SYNONYM positive regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Deleted SYNONYM positive regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Deleted SYNONYM regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Deleted SYNONYM regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Deleted SYNONYM transcriptional gene silencing
2007-05-11 Added SYNONYM heterochromatic silencing
2005-08-10 Added SYNONYM negative regulation of transcription of homeotic gene (Polycomb group)
2005-08-10 Added SYNONYM negative regulation of transcription of homeotic gene (trithorax group)
2005-08-10 Added SYNONYM positive regulation of transcription of homeotic gene (Polycomb group)
2005-08-10 Added SYNONYM positive regulation of transcription of homeotic gene (trithorax group)
2005-08-10 Added SYNONYM regulation of transcription of homeotic gene (Polycomb group)
2005-08-10 Added SYNONYM regulation of transcription of homeotic gene (trithorax group)
2005-06-23 Deleted SYNONYM heterochromatin formation
2004-04-19 Added SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2004-04-19 Added SYNONYM chromatin-mediated silencing
2004-04-16 Deleted SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2004-04-16 Deleted SYNONYM chromatin-mediated silencing
2004-03-07 Added SECONDARY GO:0016440 (transcriptional gene silencing)
2004-03-07 Added SYNONYM TGS
2004-03-07 Added SYNONYM transcriptional gene silencing
2004-02-13 Added SYNONYM heterochromatin formation
2003-06-21 Added SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2003-06-21 Added SYNONYM chromatin-mediated silencing
2002-02-06 Updated TERM chromatin silencing
2001-08-06 Added DEFINITION Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
2001-04-03 Updated TERM chromatin silencing
2001-03-30 Added TERM chromatin silencing

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM chromatin silencing
2001-04-03 Updated TERM chromatin silencing
2001-03-30 Added TERM chromatin silencing

Definition/synonyms

Timestamp Action Category Detail
2008-10-09 Deleted DEFINITION Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
2008-10-09 Added DEFINITION Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
2008-10-09 Deleted SYNONYM heterochromatic silencing
2008-10-09 Added SYNONYM heterochromatic silencing
2008-05-13 Added DEFINITION Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
2008-05-12 Deleted DEFINITION Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
2007-09-10 Deleted SYNONYM negative regulation of transcription of homeotic gene (Polycomb group)
2007-09-10 Deleted SYNONYM negative regulation of transcription of homeotic gene (trithorax group)
2007-09-10 Deleted SYNONYM positive regulation of transcription of homeotic gene (Polycomb group)
2007-09-10 Deleted SYNONYM positive regulation of transcription of homeotic gene (trithorax group)
2007-09-10 Deleted SYNONYM regulation of transcription of homeotic gene (Polycomb group)
2007-09-10 Deleted SYNONYM regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Added SYNONYM TGS
2007-08-09 Added SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2007-08-09 Added SYNONYM chromatin-mediated silencing
2007-08-09 Added SYNONYM heterochromatic silencing
2007-08-09 Added SYNONYM negative regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Added SYNONYM negative regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Added SYNONYM positive regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Added SYNONYM positive regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Added SYNONYM regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Added SYNONYM regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Added SYNONYM transcriptional gene silencing
2007-08-09 Deleted SYNONYM heterochromatic silencing
2007-08-09 Deleted SYNONYM TGS
2007-08-09 Deleted SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2007-08-09 Deleted SYNONYM chromatin-mediated silencing
2007-08-09 Deleted SYNONYM negative regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Deleted SYNONYM negative regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Deleted SYNONYM positive regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Deleted SYNONYM positive regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Deleted SYNONYM regulation of transcription of homeotic gene (Polycomb group)
2007-08-09 Deleted SYNONYM regulation of transcription of homeotic gene (trithorax group)
2007-08-09 Deleted SYNONYM transcriptional gene silencing
2007-05-11 Added SYNONYM heterochromatic silencing
2005-08-10 Added SYNONYM negative regulation of transcription of homeotic gene (Polycomb group)
2005-08-10 Added SYNONYM negative regulation of transcription of homeotic gene (trithorax group)
2005-08-10 Added SYNONYM positive regulation of transcription of homeotic gene (Polycomb group)
2005-08-10 Added SYNONYM positive regulation of transcription of homeotic gene (trithorax group)
2005-08-10 Added SYNONYM regulation of transcription of homeotic gene (Polycomb group)
2005-08-10 Added SYNONYM regulation of transcription of homeotic gene (trithorax group)
2005-06-23 Deleted SYNONYM heterochromatin formation
2004-04-19 Added SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2004-04-19 Added SYNONYM chromatin-mediated silencing
2004-04-16 Deleted SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2004-04-16 Deleted SYNONYM chromatin-mediated silencing
2004-03-07 Added SYNONYM TGS
2004-03-07 Added SYNONYM transcriptional gene silencing
2004-02-13 Added SYNONYM heterochromatin formation
2003-06-21 Added SYNONYM chromatin-mediated maintenance of transcriptional inactivation
2003-06-21 Added SYNONYM chromatin-mediated silencing
2001-08-06 Added DEFINITION Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin.

Relationships

Timestamp Action Category Detail
2008-10-09 Deleted RELATION is a GO:0031507 (heterochromatin assembly)
2008-10-02 Added RELATION is a GO:0031507 (heterochromatin assembly)
2008-09-06 Deleted RELATION is a GO:0031507 (heterochromatin assembly)
2008-04-01 Updated RELATION is a GO:0016458 (gene silencing)
2008-04-01 Updated RELATION is a GO:0045892 (negative regulation of transcription, DNA-templated)
2008-04-01 Updated RELATION is a GO:0045814 (negative regulation of gene expression, epigenetic)
2008-04-01 Updated RELATION is a GO:0031507 (heterochromatin assembly)

Other

Timestamp Action Category Detail
2004-03-07 Added SECONDARY GO:0016440 (transcriptional gene silencing)
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